Search
Search Results
-
Quantitative evaluation of citrullinated fibrinogen for detection of neutrophil extracellular traps
Activated neutrophils release neutrophil extracellular traps (NETs) composed of chromatin filaments containing bactericidal proteins and enzymes....
-
PADI2 gene confers susceptibility to breast cancer and plays tumorigenic role via ACSL4, BINC3 and CA9 signaling
BackgroundPeptidylarginine deiminase (PAD) post-translationally converts arginine residues to citrulline residues. Recent studies have suggested that...
-
PAD Activation in Arthritis
The findings that citrullinated proteins are targeted by the most specific immune response in rheumatoid arthritis, and that citrullination also... -
Turning White Matter “Inside-Out” by Hyper-deimination of Myelin Basic Protein (MBP)
The myelin sheath of the nervous system provides trophic and metabolic support to underlying axons and facilitates faster action potential... -
-
-
-
Deimination in Skin and Regulation of Peptidylarginine Deiminase Expression in Keratinocytes
The existence of citrulline in proteins was first described in the skin. In a paper published in Nature in 1958, George Rogers reported citrulline in... -
Physiological Pathways of PAD Activation and Citrullinated Epitope Generation
The peptidylarginine deiminase (PAD) enzymes hydrolyze arginine residues to create the nonnative amino acid citrulline (a process called...