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Visualizing NETosis Using a Novel Neutrophil Extracellular Trap-Specific Marker
As the most abundant leukocyte in circulation, the neutrophil plays a far-reaching role in maintaining homeostasis. Within the context of disease,...
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The Effect of Vitamin D3 on Neutrophil Extracellular Trap Formation in High-Glucose Conditions
NETosis, i.e ., the formation of neutrophil extracellular traps (NET), and neutrophil autophagy are important elements in the pathogenesis and the...
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Placental neutrophil reverse trans-migration and maternal serum neutrophil extracellular trap expression in HIV infection co-morbid pre-eclampsia in women of African ancestry
Neutrophil extracellular traps (NETs) and placental neutrophil reverse transmigration (r-TM) are implicated in the pathogenesis of pre-eclampsia...
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Screening and Identification of Neutrophil Extracellular Trap-related Diagnostic Biomarkers for Pediatric Sepsis by Machine Learning
Neutrophil extracellular trap (NET) is released by neutrophils to trap invading pathogens and can lead to dysregulation of immune responses and...
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Vascular smooth muscle cells in response to cholesterol crystals modulates inflammatory cytokines release and promotes neutrophil extracellular trap formation
BackgroundThe formation and accumulation of cholesterol crystals (CC) at the lesion site is a hallmark of atherosclerosis. Although studies have...
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Neutrophils and neutrophil extracellular traps in oral health and disease
Neutrophils perform essential functions in antimicrobial defense and tissue maintenance at mucosal barriers. However, a dysregulated neutrophil...
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Non-apoptotic Cell Death Control of Neutrophil Extracellular Trap Formation
Neutrophil extracellular traps (NETs) are networks of chromatin and microbicidal proteins released by neutrophils in response to infection and tissue...
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Platelet-derived extracellular vesicles promote endothelial dysfunction in sepsis by enhancing neutrophil extracellular traps
BackgroundThe role of platelet-derived extracellular vesicles (PEVs) in the development of sepsis was investigated in this study.
Methods ...
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Neutrophil extracellular trap induction through peptidylarginine deiminase 4 activity is involved in 2,4,6-trinitrobenzenesulfonic acid-induced colitis
Neutrophil extracellular traps (NETs) are induced in the innate immune response against infectious agents and are also implicated in the pathogenesis...
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Impaired balance between neutrophil extracellular trap formation and degradation by DNases in COVID-19 disease
BackgroundThrombo-inflammation and neutrophil extracellular traps (NETs) are exacerbated in severe cases of COVID-19, potentially contributing to...
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Neutrophil extracellular traps in intracerebral hemorrhage: implications for pathogenesis and therapeutic targets
Intracerebral hemorrhage is a common neurological disease, and its pathological mechanism is complex. As the first recruited leukocyte subtype after...
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Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1α/ASK1/JNK signaling pathway in mice with traumatic brain injury
BackgroundNeuroinflammation is one of the most important pathogeneses in secondary brain injury after traumatic brain injury (TBI). Neutrophil...
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Neutrophil Extracellular Trap Formation Potential Correlates with Lung Disease Severity in COVID-19 Patients
Severe lung inflammation is common in life-threatening coronavirus disease 2019 (COVID-19). This study tested the hypothesis that polymorphonuclear...
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Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases
Systemic autoimmune diseases are characterized by the failure of the immune system to differentiate self from non-self. These conditions are...
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SIRT1-Mediated HMGB1 Deacetylation Suppresses Neutrophil Extracellular Traps Related to Blood–Brain Barrier Impairment After Cerebral Venous Thrombosis
Cerebral venous thrombosis (CVT) is a neurovascular disease with recently increasing incidence. Aseptic inflammatory responses play an important role...
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Significance of neutrophil extracellular traps-related gene in the diagnosis and classification of atherosclerosis
Atherosclerosis (AS) is a pathological process associated with various cardiovascular diseases. Upon different stimuli, neutrophils release reticular...
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IgG Stimulates the Formation of Neutrophil Extracellular Traps and Modifies Their Structure
We studied the neutrophils and monocytes obtained from 37 patients with various inflammatory diseases such as psoriasis, acute infectious process in...
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Neutrophils and neutrophil extracellular traps in cancer: promising targets for engineered nanomaterials
Neutrophils are the most abundant white blood cells in circulation and constitute up to 60% of circulating leukocytes. Neutrophils play a significant...
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Wip1 inhibits neutrophil extracellular traps to promote abscess formation in mice by directly dephosphorylating Coronin-1a
Neutrophil extracellular traps (NETs) participate in the rapid inhibition and clearance of pathogens during infection; however, the molecular...
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Neutrophil extracellular traps primed intercellular communication in cancer progression as a promising therapeutic target
In addition to the anti-infection response, neutrophils are linked to tumor progression through the secretion of inflammation components and...
