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A novel NET-related gene signature for predicting DLBCL prognosis
BackgroundDiffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy. Neutrophil extracellular traps (NETs) are pathogen-trap** structures...
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Rethinking U-Net Deep Neural Network for Spine Radiographic Images-Based Spine Vertebrae Segmentation
ObjectiveToday, lifestyle changes cause spine abnormalities. Radiographic images are used to diagnose scoliosis, a common spine abnormality. Existing...
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The survival benefit of adjuvant trastuzumab with or without chemotherapy in the management of small (T1mic, T1a, T1b, T1c), node negative HER2+ breast cancer
There is limited data regarding the added benefit of adjuvant systemic therapy in the management of small, node-negative, HER2+ breast cancer. In a...
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What have we learnt from the past – would treatment decisions for GEP-NET patients differ between 2012 to 2016 by the new recommendations in 2022?
BackgroundGastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a heterogeneous group of tumors with a broad range of local and systemic...
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Predicting cancer drug TARGETS - TreAtment Response Generalized Elastic-neT Signatures
We are now in an era of molecular medicine, where specific DNA alterations can be used to identify patients who will respond to specific drugs....
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Insecticide-treated bed net utilization and associated factors among pregnant women in Ethiopia: a systematic review and meta-analysis
BackgroundMalaria infection during pregnancy endangers the pregnant woman, fetus, and newborn child. Thus, the use of an insecticide-treated net...
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A nomogram based on peripheral lymphocyte for predicting 8-year survival in patients with prostate cancer: a single-center study using LASSO-cox regression
PurposeThe purpose of this study was to develop a functional clinical nomogram for predicting 8-year overall survival (OS) of patients with prostate...
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Prediction of complete regression in fertility-sparing patients with endometrial cancer and apical hyperplasia: the GLOBAL model in a large Chinese cohort
BackgroundFertility preservation treatment is increasingly essential for patients with apical endometrial hyperplasia (AEH) and early endometrial...
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Advantages of the net benefit regression framework for trial-based economic evaluations of cancer treatments: an example from the Canadian Cancer Trials Group CO.17 trial
BackgroundEconomic evaluations commonly accompany trials of new treatments or interventions; however, regression methods and their corresponding...
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Implementation of an Evidence-Based Intervention with Safety Net Clinics to Improve Mammography Appointment Adherence Among Underserved Women
The Peace of Mind Program is an evidence-based intervention to improve mammography appointment adherence in underserved women. The aim of this study...
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Effect of bed net colour and shape preferences on bed net usage: a secondary data analysis of the 2017 Malawi Malaria Indicator Survey
BackgroundMalaria remains a significant cause of morbidity and mortality in the paediatric population in Malawi. Insecticide-treated bed nets are a...
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Predicting Spray Dried Dispersion Particle Size Via Machine Learning Regression Methods
Spray dried dispersion particle size is a critical quality attribute that impacts bioavailability and manufacturability of the spray drying process...
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External validation of nomograms including MRI features for the prediction of side-specific extraprostatic extension
BackgroundPrediction of side-specific extraprostatic extension (EPE) is crucial in selecting patients for nerve-sparing radical prostatectomy (RP)....
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Small-scale field evaluation of PermaNet® Dual (a long-lasting net coated with a mixture of chlorfenapyr and deltamethrin) against pyrethroid-resistant Anopheles gambiae mosquitoes from Tiassalé, Côte d’Ivoire
BackgroundDue to the rapid expansion of pyrethroid-resistance in malaria vectors in Africa, Global Plan for Insecticide Resistance Management (GPIRM)...
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An updated model for predicting side-specific extraprostatic extension in the era of MRI-targeted biopsy
PurposeAccurate prediction of extraprostatic extension (EPE) is pivotal for surgical planning. Herein, we aimed to provide an updated model for...
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Nomogram to predict central lymph node metastasis in papillary thyroid carcinoma
Central lymph node metastasis (CLNM) of papillary thyroid carcinoma (PTC) is common. In our study, we built a nomogram to predict CLNM. We...
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Timing of adjuvant chemotherapy initiation and mortality among colon cancer patients at a safety-net health system
BackgroundPrior studies reported survival benefits from early initiation of adjuvant chemotherapy for stage III colon cancer, but this evidence was...
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Biopsy-free AI-aided precision MRI assessment in prediction of prostate cancer biochemical recurrence
BackgroundTo investigate the predictive ability of high-throughput MRI with deep survival networks for biochemical recurrence (BCR) of prostate...
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A nomogram for predicting the hospital-acquired infections in children with spinal cord injuries: a retrospective, multicenter, observational study
Study designRetrospective cohort study.
ObjectivesHospital-acquired infections (HAIs) pose a significant risk for pediatric patients with spinal...
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Factors associated with use of insecticide-treated net for malaria prevention in Manica District, Mozambique: a community-based cross-sectional survey
BackgroundInsecticide-treated net (ITN) use is crucial for preventing malaria infection. Despite significant improvements in ITN access and use over...
