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Neocortex neurogenesis and maturation in the African greater cane rat
BackgroundNeocortex development has been extensively studied in altricial rodents such as mouse and rat. Identification of alternative animal models...
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Influence of age on nicotinic cholinergic regulation of blood flow in rat’s olfactory bulb and neocortex
The olfactory bulb receives cholinergic basal forebrain inputs as does the neocortex. With a focus on nicotinic acetylcholine receptors (nAChRs),...
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A sensory–motor theory of the neocortex
Recent neurophysiological and neuroanatomical studies suggest a close interaction between sensory and motor processes across the neocortex. Here, I...
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Effects of Chloral Hydrate on the Morphogenetic Characteristics of the Neocortex and Functional Status in Elderly Male Rats
There is a need to take the characteristics and possible influences of animals’ age and the anesthesia used in experiments on their outcomes into...
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Salifen Prevents Perinatal Hypoxia-Induced Cognitive Impairments and Changes in the Expression of GABAB Receptors in the Rat Neocortex
We report here a study examining the effects of acute normobaric hypoxia in the early postnatal period of development (postnatal day 2) on learning...
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Behavior-relevant top-down cross-modal predictions in mouse neocortex
Animals adapt to a constantly changing world by predicting their environment and the consequences of their actions. The predictive coding hypothesis...
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Microglia-derived CCL2 has a prime role in neocortex neuroinflammation
BackgroundIn myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE), several areas of demyelination are...
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Mechanisms of Functioning of the Connectome Including the Neocortex, Hippocampus, Basal Ganglia, Cerebellum, and Thalamus
Possible mechanisms of the interactions of neuron functioning in the connectome including topographically connected areas of the neocortex,...
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A new 3D myeloarchitectonic map of the human neocortex based on data from the Vogt–Vogt school
During the period extending from 1900 to 1970, Oskar and Cécile Vogt and their numerous collaborators (‘the Vogt–Vogt school’) published a large...
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Metabolic lactate production coordinates vasculature development and progenitor behavior in the develo** mouse neocortex
Proper neural progenitor behavior in conjunction with orderly vasculature formation is fundamental to the development of the neocortex. However, the...
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Homology of neocortical areas in rats and primates based on cortical type analysis: an update of the Hypothesis on the Dual Origin of the Neocortex
Sixty years ago, Friedrich Sanides traced the origin of the tangential expansion of the primate neocortex to two ancestral anlagen in the allocortex...
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Direct association with the vascular basement membrane is a frequent feature of myelinating oligodendrocytes in the neocortex
BackgroundOligodendrocyte lineage cells interact with the vasculature in the gray matter. Physical and functional interactions between blood vessels...
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Inflammatory panel cytokines are elevated in the neocortex of late-stage Alzheimer’s disease but not Lewy body dementias
BackgroundChronically dysregulated neuroinflammation has been implicated in neurodegenerative dementias, with separate studies reporting increased...
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Ketamine triggers a switch in excitatory neuronal activity across neocortex
The brain can become transiently disconnected from the environment while maintaining vivid, internally generated experiences. This so-called...
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Development of myelin in fetal and postnatal neocortex of the pig, the European wild boar Sus scrofa
Myelination of the neocortex of altricial species is mostly a postnatal event, and the appearance of myelin has been associated with the end of the...
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Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE)
Synaptic vesicle glycoprotein-2 (SV2) is a family of proteins consisting of SV2A, SV2B, and SV2C. This protein family has attracted attention in...
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CB2 receptors modulate seizure-induced expression of pro-inflammatory cytokines in the hippocampus but not neocortex
We compared neuroinflammatory responses induced by nonconvulsive and convulsive seizures and analyzed the role that may be played by cannabinoid CB2...
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Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex
Mammalian neocortical neurons span one of the most diverse cell type spectra of any tissue. Cortical neurons are born during embryonic development,...
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The distribution and density of Huntingtin inclusions across the Huntington disease neocortex: regional correlations with Huntingtin repeat expansion independent of pathologic grade
Huntington disease is characterized by progressive neurodegeneration, especially of the striatum, and the presence of polyglutamine huntingtin (HTT)...
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Proteomic features of gray matter layers and superficial white matter of the rhesus monkey neocortex: comparison of prefrontal area 46 and occipital area 17
In this novel large-scale multiplexed immunofluorescence study we comprehensively characterized and compared layer-specific proteomic features within...
