Search
Search Results
-
Senescent cancer cell-derived nanovesicle as a personalized therapeutic cancer vaccine
The development of therapeutic cancer vaccines (TCVs) that provide clinical benefits is challenging mainly due to difficulties in identifying...
-
-
Matrix-bound nanovesicle-associated IL-33 supports functional recovery after skeletal muscle injury by initiating a pro-regenerative macrophage phenotypic transition
Injuries to skeletal muscle are among the most common injuries in civilian and military populations, accounting for nearly 60% of extremity injuries....
-
Novel Gellan Gum-Based In Situ Nanovesicle Formulation of Docetaxel for Its Localized Delivery Using Depot Formation
In the present study, different in situ hydrogel formulations of docetaxel (DTX) based on biocompatible polymers such as Hyaluronic Acid (HA),...
-
Nanovesicular-Mediated Intranasal Drug Therapy for Neurodegenerative Disease
Numerous neurodegenerative conditions, such as Alzheimer’s, Huntington’s, Parkinson’s, amyotrophic lateral sclerosis, and glioblastoma multiform are...
-
Nanosized drug delivery systems modulate the immunosuppressive microenvironment to improve cancer immunotherapy
Immunotherapy that activates immune systems for combating cancer has yielded considerable clinical benefits recently. However, the immunosuppressive...
-
Synthesis, Characterization, and Drug Delivery Application of Self-assembling Amphiphilic Cyclodextrin
The main aim of the research was to synthesize amphiphilic cyclodextrin (AMCD) by substituting C12 alkyl chain to a β-cyclodextrin (βCD) in a single...
-
Advancing therapeutic efficacy: nanovesicular delivery systems for medicinal plant-based therapeutics
The utilization of medicinal plant extracts in therapeutics has been hindered by various challenges, including poor bioavailability and stability...
-
Recent Trends in Nanomedicine for Diagnosis and Treatment of Pulmonary Diseases
Chronic inflammatory mediated pulmonary diseases cause millions of deaths and are responsible for significant morbidity and mortality at global level...
-
OX26-cojugated gangliosilated liposomes to improve the post-ischemic therapeutic effect of CDP-choline
Cerebrovascular impairment represents one of the main causes of death worldwide with a mortality rate of 5.5 million per year. The disability of 50%...
-
Cell-derived biomimetic nanoparticles for the targeted therapy of ALI/ARDS
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common clinical critical diseases with high morbidity and mortality....
-
Flow Cytometry for Single Extracellular Vesicle Analysis
Extracellular vesicles (EVs) are nanoscale lipid bilayer-enclosed vesicles secreted by cells to mediate intercellular communication via the transfer...
-
Engineered nanomedicines block the PD-1/PD-L1 axis for potentiated cancer immunotherapy
Immunotherapy, in particular immune checkpoint blockade (ICB) therapy targeting the programmed cell death-1 (PD-1)/programmed cell death ligand-1...
-
Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine
PurposeThis study establishes a multiphysics simulation platform for both conventional and targeted thrombolysis using tissue plasminogen activator...
-
Role of Block Copolymers in Topical Drug Delivery
In topical drug delivery, drugs are delivered to the skin with the intention of either treating skin conditions or slowly and gradually entering the...
-
Exosomes in the pathogenesis and treatment of cancer-related cachexia
Cancer-related cachexia is a metabolic syndrome characterized by weight loss, adipose tissue decomposition, and progressive skeletal muscle atrophy....
-
Technologies for Visualization and Tracking of Extracellular Vesicles
Extracellular vesicles (EVs) are intercellular communicators that can deliver important biological molecules to recipient cells to participate in the...
-
Inhalable CAR-T cell-derived exosomes as paclitaxel carriers for treating lung cancer
BackgroundNon-small cell lung cancer (NSCLC) is a worldwide health threat with high annual morbidity and mortality. Chemotherapeutic drugs such as...
-
Resistance to Immunotherapy in Breast Cancer
Breast cancer is the most common and second most deadly disease in women worldwide, with breast cancer screening resulting in a steady decline in...