Search
Search Results
-
Evaluation of Emulgel and Nanostructured Lipid Carrier-Based Gel Formulations for Transdermal Administration of Ibuprofen: Characterization, Mechanical Properties, and Ex-Vivo Skin Permeation
In transdermal applications of nonsteroidal anti-inflammatory drugs, the rheological and mechanical properties of the dosage form affect the...
-
Hyaluronic acid derivative-modified nano-structured lipid carrier for cancer targeting and therapy
To reduce the problems of poor solubility, high in vivo dosage requirement, and weak targeting ability of paclitaxel (PTX), a hyaluronic...
-
PEGylated Lipid Nanocontainers Tailored with Sunseed-Oil-Based Solidified Reverse Micellar Solution for Enhanced Pharmacodynamics and Pharmacokinetics of Metformin
PurposePoor oral absorption, low bioavailability, short half-life, and gastrointestinal effects due to high dose of metformin required in the...
-
Lipid-Based Nanocarriers in the Treatment of Glioblastoma Multiforme (GBM): Challenges and Opportunities
Glioblastoma multiforme (also known as glioblastoma; GBM) is one of the most malignant types of brain tumors that occurs in the CNS. Treatment...
-
Development of core–shell structured nanoparticle for sequential release of tariquidar and docetaxel to overcome multi drug-resistant cancer
PurposeWe developed a core–shell (CS) nanoparticle, docetaxel (DTX)-loaded core and tariquidar (TRQ)-loaded shell conjugated with PEG and RIPL...
-
Demystifying the potential of lipid-based nanocarriers in targeting brain malignancies
Drug targeting for brain malignancies is restricted due to the presence of the blood–brain barrier (BBB) and blood–brain tumor barrier (BBTB), which...
-
Lipid-Based Nanocarriers via Nose-to-Brain Pathway for Central Nervous System Disorders
Neurodegenerative disorders are distinguished by the gradual deterioration of the nervous system’s structure and function due to oxidative stress,...
-
LipNanoCar Technology – A Versatile and Scalable Technology for the Production of Lipid Nanoparticles
The extensive knowledge in the miniemulsion technique used in biocatalysis applications by the authors allowed the development of drug delivery...
-
Nanomedicines in the Treatment of Nervous System Disorders
The chapter overviews different diseases of central nervous system (CNS), the problems associated with conventional therapies to CNS and transport...
-
Functionalized Lipidic Nanoparticles: Smartly Engineered Lipidic Theragnostic Nanomedicines
The concept of theranostics revolutionized with the inception of surface engineering of nanolipidic carriers. In the modern era of precision...
-
Nanomedicines in the Treatment of Skin Diseases
In this chapter, we will discuss the current and potential applications of nanotechnology in the treatment of skin diseases. The use of nanomedicine...
-
Microemulsion as a promising carrier for nose to brain delivery: journey since last decade
BackgroundTight junctions and efflux transporters are two chief bodyguards of the blood–brain barrier that protect the brain and create challenges...
-
Current Status of Nanomedicines in Clinical Practice
Research on bioactive chemicals and the pharmacological prospective of numerous plant species is being emphasized by the scientific community....
-
Emerging Technologies to Target Drug Delivery to the Skin – the Role of Crystals and Carrier-Based Systems in the Case Study of Dapsone
Dapsone (DAP) is a long-established molecule that remains a promising therapeutic agent for various diseases mainly because it combines antimicrobial...
-
Formulation and Characterization of Silibinin Entrapped Nano-Liquid Crystals for Activity against Aβ1-42 Neurotoxicity in In-Vivo Model
Silibinin (SIL) Encapsulated Nanoliquid Crystalline (SIL-NLCs) particles were prepared to study neuroprotective effect against amyloid beta (Aβ 1-42 )...
-
Stabilized oral nanostructured lipid carriers of Adefovir Dipivoxil as a potential liver targeting: Estimation of liver function panel and uptake following intravenous injection of radioiodinated indicator
PurposeAdefovir dipivoxil (AD), a nucleoside reverse transcriptase inhibitor is effective against Hepatitis B virus. Its poor oral bioavailability...
-
Multifunctional lipidic nanocarriers for effective therapy of glioblastoma: recent advances in stimuli-responsive, receptor and subcellular targeted approaches
BackgroundGlioblastoma, or glioblastoma multiforme (GBM), remains a fatal cancer type despite the remarkable progress in understanding the genesis...
-
Nanovesicular-Mediated Intranasal Drug Therapy for Neurodegenerative Disease
Numerous neurodegenerative conditions, such as Alzheimer’s, Huntington’s, Parkinson’s, amyotrophic lateral sclerosis, and glioblastoma multiform are...
-
Exploration of novel drug delivery systems in topical management of osteoarthritis
Osteoarthritis is one of the foremost disabling disorders in the world. There is no definitive treatment to prevent the progression of...
-
Advantages of Nanomedicine Over Conventional Therapeutics
The word nanotechnology fascinates masses and drives out interest from all corners of life including general public but especially for scientists...