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Exogenous NT-3 Promotes Phenotype Switch of Resident Macrophages and Improves Sciatic Nerve Injury through AMPK/NF-κB Signaling Pathway
Neurotrophin-3 (NT-3) is an important family of neurotrophic factors with extensive neurotrophic activity, which can maintain the survival and...
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AAV1.NT-3 gene therapy for X-linked Charcot–Marie–Tooth neuropathy type 1
X-linked Charcot-Marie-Tooth neuropathy (CMTX) is caused by mutations in the gene encoding Gap Junction Protein Beta-1 (GJB1)/Connexin32 (Cx32) in...
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Distinct Effects of BDNF and NT-3 on the Dendrites and Presynaptic Boutons of Develo** Olfactory Bulb GABAergic Interneurons In Vitro
Brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3) are known to regulate neuronal morphology and the formation of neural circuits,...
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Opposite Roles of NT-3 and BDNF in Synaptic Remodeling of the Inner Ear Induced by Electrical Stimulation
With the development of neural prostheses, neural plasticity including synaptic remodeling under electrical stimulation is drawing more and more...
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Neurotrophin-3 promotes peripheral nerve regeneration by maintaining a repair state of Schwann cells after chronic denervation via the TrkC/ERK/c-Jun pathway
BackgroundMaintaining the repair phenotype of denervated Schwann cells in the injured distal nerve is crucial for promoting peripheral nerve...
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Cost-effectiveness of ivosidenib versus chemotherapy for previously treated IDH1-mutant advanced intrahepatic cholangiocarcinoma in Taiwan
BackgroundInternational guidelines recommend ivosidenib followed by modified FOLFOX (mFOLFOX) for advanced intrahepatic cholangiocarcinoma (ICC) with...
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Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy
PurposeGastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) form a rare and remarkably heterogeneous group of tumors. Therefore, establishing...
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Detection and characterization of a putative emaravirus infecting Clematis brevicaudata DC. in China
A novel emaravirus, tentatively named “clematis yellow mottle associated virus” (CYMaV), was identified through transcriptome sequencing and RT-PCR...
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Molecular characterization of a divergent genetic variant of wheat Eqlid mosaic virus from a Texas wheat field
Investigations conducted during the spring 2020 season to diagnose the associated viral agent of a severe mosaic disease of wheat in a Texas...
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Complete genome sequence of Paris polyphylla chlorotic mottle virus infecting Paris polyphylla var. yunnanensis in southwest China
A novel virus infecting a Paris polyphylla var. yunnanensis plant, tentatively named "Paris polyphylla chlorotic mottle virus" (PpCMV), was...
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MicroRNA mmu-miR-511-5p: A promising Diagnostic Biomarker in Experimental Toxoplasmosis Using Different Strains and Infective Doses in Mice with Different Immune States Before and After Treatment
PurposeSearching for a novel early diagnostic biomarker for toxoplasmosis, real-time-PCR was currently used to measure the serum mmu-miR-511-5p level...
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Correction to: Opposite Roles of NT-3 and BDNF in Synaptic Remodeling of the Inner Ear Induced by Electrical Stimulation
The original version of this article unfortunately contained an error in Figure 9.
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Complete genome sequence of a divergent strain of cardamom mosaic virus
Cardamom mosaic virus (CdMV; genus Macluravirus ), which causes mosaic ( katte ) disease in cardamom, is a highly variable member of the family Potyviridae...
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Complete genome sequence analysis of a novel citlodavirus isolated from the leaves of Myrica rubra in Yunnan
Through high-throughput sequencing, a novel citlodavirus, tentatively named “Myrica rubra citlodavirus 1” (MRV1, accession no. OP374189), was...
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A novel alternavirus with three dsRNA segments from Fusarium pseudograminearum, the pathogen of Fusarium crown rot in wheat
Three dsRNA segments were detected in Fusarium pseudograminearum strain CF14029, a pathogen causing Fusarium crown rot in China. Characterization and...
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Characterization of a novel endornavirus isolated from the phytopathogenic fungus Rhizoctonia solani
Rhizoctonia solani endornavirus 8 (RsEV8) was isolated from strain XY175 of Rhizoctonia solani AG-1 IA . The full-length genome of RsEV8 is 16,147...
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Identification and molecular characterization of a novel cytorhabdovirus from rose plants (Rosa chinensis Jacq.)
A novel negative-sense single-stranded RNA virus, tentatively named "rose-associated cytorhabdovirus" (RaCV), was identified by high-throughput...
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Neurotrophins and Phytochemicals: Potential Partners to Combat Neurodegenerative Diseases
Neurotrophins and phytochemicals have emerged as promising areas of research in the field of neuroscience and human health. Neurotrophins are a group...
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The Molecular Pathway of p75 Neurotrophin Receptor (p75NTR) in Parkinson’s Disease: The Way of New Inroads
Parkinson’s disease (PD) is a chronic and progressive neurodegenerative disease of the brain. PD is characterized by motor and non-motor symptoms....
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Impact of HIF prolyl hydroxylase inhibitors in heart failure patients with renal anemia
ObjectiveHypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitors are a new class of anti-anemia agents. We retrospectively evaluated the...
