Search
Search Results
-
Neutrophil gelatinase-associated lipocalin (NGAL) and tumor necrosis factor-α (TNF-α) levels in patients with schizophrenia
RationaleAlthough the immune system is thought to contribute to the etiology of schizophrenia, the mechanism has not been elucidated. Clarifying the...
-
The Expression of Markers of Acute Kidney Injury Kim1 and NGAL after Administration of High Doses of Lithium Carbonate in Mice with Engrafted Skin Melanoma B16
The expression of marker proteins of acute kidney injury after administration of high doses of lithium carbonate was assessed to evaluate the...
-
Diagnostic value of cerebrospinal fluid Neutrophil Gelatinase-Associated Lipocalin for differentiation of bacterial meningitis from tuberculous meningitis or cryptococcal meningitis: a prospective cohort study
BackgroundThe early differential diagnosis between bacterial meningitis (BM) and tuberculous meningitis (TBM) or cryptococcal meningitis (CM) remains...
-
Silencing HE4 alleviates the renal fibrosis in lupus nephritis mice by regulating the C3/MMPs/prss axis
To explore the regulatory effect of human epididymis protein 4 (HE4) on renal fibrosis in mice with lupus nephritis (LN) and the underlying...
-
Sex-dependent expression of neutrophil gelatinase-associated lipocalin in aortic stenosis
BackgroundAccumulating evidence suggest the existence of sex-related differences in the pathogenesis of aortic stenosis (AS) with inflammation,...
-
Impacts of age, type 2 diabetes, and hypertension on circulating neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 after prolonged work in the heat in men
PurposeProlonged work in the heat increases the risk of acute kidney injury (AKI) in young men. Whether aging and age-associated chronic disease may...
-
Novel mechanism of the COVID-19 associated coagulopathy (CAC) and vascular thromboembolism
Previous studies from our laboratory revealed that SARS-CoV-2 spike protein (SP) administration to a genetically engineered model expressing the...
-
The power of trans-sodium crocetinate: exploring its renoprotective effects in a rat model of colistin-induced nephrotoxicity
Colistin, a multidrug-resistant gram-negative bacterial infection medication, has been associated with renal impairment and failure. Trans-sodium...
-
Stevia extract safeguards rats from diabetic renal injury by mitigating markers of inflammation, oxidative stress, and apoptosis
ObjectiveThis study will figure out if stevia extract, a herb with anti-inflammatory and antioxidant characteristics, is effective in treating...
-
Effect of verbascoside against acute kidney injury induced by rhabdomyolysis in rats
Rhabdomyolysis is a pathological condition caused by muscle tissue degradation. In this condition, intracellular contents enter the bloodstream, and...
-
Protective effects of nodosin against lipopolysaccharide-induced acute kidney injury through regulation of oxidative stress, inflammation, and ferroptosis in rats
This research aimed to explore the impact of nodosin on lipopolysaccharide (LPS)-induced acute kidney injury (AKI) in rats. The study involved...
-
Sildenafil and furosemide nanoparticles as a novel pharmacological treatment for acute renal failure in rats
Hospitalized patients often develop acute renal failure (ARF), which causes severe morbidity and death. This research investigates the potential...
-
Chemiluminescence Immunoassay Method of Urinary Liver Fatty-acid-binding Protein as a Promising Candidate for Kidney Disease
Liver fatty acid binding protein (L-FABP) is an intercellular lipid chaperone protein that selectively combines with unsaturated free fatty acids and...
-
Role of uranium toxicity and uranium-induced oxidative stress in advancing kidney injury and endothelial inflammation in rats
ObjectiveUranium exposure may cause serious pathological injury to the body, which is attributed to oxidative stress and inflammation. However, the...
-
Nifuroxazide attenuates indomethacin-induced renal injury by upregulating Nrf2/HO-1 and cytoglobin and suppressing NADPH-oxidase, NF-κB, and JAK-1/STAT3 signals
Indomethacin (INDO) is an NSAID with remarkable efficacy and widespread utilization for alleviating pain. Nevertheless, renal function impairment is...
-
Targeting RNA-binding protein HuR to inhibit the progression of renal tubular fibrosis
BackgroundUpregulation of an RNA-binding protein HuR has been implicated in glomerular diseases. Herein, we evaluated whether it is involved in renal...
-
Infliximab abrogates adenine-induced chronic kidney disease via modulation of the MAPK/JNK/ASK signaling pathway in rats
Chronic kidney disease (CKD) is a prominent cause of death worldwide. Infliximab is one of the anti-TNF-α; herein, we studied the effect of...
-
Allicin ameliorates sepsis-induced acute kidney injury through Nrf2/HO-1 signaling pathway
Acute kidney injury (AKI) is a complication that can be induced by different factors. Allicin is a class of organic sulfur compounds with anticancer...
-
A pilot investigation of the association between HIV-1 Vpr amino acid sequence diversity and the tryptophan-kynurenine pathway as a potential mechanism for neurocognitive impairment
HIV infection compromises both the peripheral and central immune systems due to its pathogenic and neuropathogenic features. The mechanisms driving...
-
Drug-Induced Nephrotoxicity and Use of Biomarkers
Nephrotoxicity has been defined as renal injury that is caused due to direct or indirect exposure, mostly to drugs and other exogenous industrial or...