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Malaria attributable fractions with changing transmission intensity: Bayesian latent class vs logistic models
BackgroundAsymptomatic carriage of malaria parasites is common in high transmission intensity areas and confounds clinical case definitions for...
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Multinomial Regression for Outcome Categories (55 Patients)
This chapter will assess, whether multinomial regression can be trained to make predictions about. -
Methotrexate is associated with decreased total thyroxine in patients with rheumatoid arthritis
BackgroundRheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by joint swelling, pain, and deformation. RA patients...
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Association between preoperative anxiety states and postoperative complications in patients with esophageal cancer and COPD: a retrospective cohort study
BackgroundEsophageal cancer brings emotional changes, especially anxiety to patients. Co-existing anxiety makes the surgery difficult and may cause...
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Environmental barriers perceived by the Finnish population with spinal cord injury: a cross-sectional survey
Study designCross-sectional survey of the Finnish population with spinal cord injury (SCI).
ObjectivesTo explore the frequencies of perceived...
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Serum metabolite signatures of cardiac function and morphology in individuals from a population-based cohort
BackgroundChanges in serum metabolites in individuals with altered cardiac function and morphology may exhibit information about cardiovascular...
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Effect of rurality and travel distance on contralateral prophylactic mastectomy for unilateral breast cancer
PurposeDespite lack of survival benefit, demand for contralateral prophylactic mastectomy (CPM) to treat unilateral breast cancer remains high. High...
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A predictive model based on site-specific risk factors of recurrence regions in endometrial cancer patients
ObjectiveThis study investigated site-specific differences in clinical factors for recurrence in patients who were newly diagnosed and treated for...
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High-Density Lipoprotein Is Associated with Leukoaraiosis Severity in Patients with Acute Ischemic Stroke
Many patients with acute ischemic stroke (AIS) are found to accompany with leukoaraiosis (LA) in brain imaging. The risk factors of LA in patients...
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Associations between pregnancy-related factors and birth characteristics with risk of rare uterine cancer subtypes: a Nordic population-based case–control study
PurposeUterine sarcomas are a rare group of uterine malignancies. Due to the low incidence and changes in uterine sarcoma classification, risk...
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Computationally efficient whole-genome regression for quantitative and binary traits
Genome-wide association analysis of cohorts with thousands of phenotypes is computationally expensive, particularly when accounting for sample...
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Classic Machine Learning Methods
In this chapter, we present the main classic machine learning methods. A large part of the chapter is devoted to supervised learning techniques for... -
Predicting change in labour market participation of people with spinal cord injury (SCI): longitudinal evidence from the Swiss SCI community survey
Study designLongitudinal, population-based survey.
ObjectiveTo examine change in labour market participation (LMP) of people with spinal cord injury...
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BMI trajectory of rapid and excessive weight gain during adulthood is associated with bone loss: a cross-sectional study from NHANES 2005–2018
BackgroundStudies have examined the effect of weight change on osteoporosis, but the results were controversial. Among them, few had looked at weight...
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Assessing the use of anti-PD1 monotherapy as adjuvant therapy and determinants of treatment choice in stage III cutaneous melanoma in the US
BackgroundThe objective of this study was to describe real-world adjuvant therapy (AT) use by disease substage and assess determinants of treatment...
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A regional genomic surveillance program is implemented to monitor the occurrence and emergence of SARS-CoV-2 variants in Yubei District, China
BackgroundIn December 2022, Chongqing experienced a significant surge in coronavirus disease 2019 (COVID-19) epidemic after adjusting control...
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Unraveling the Genetic Associations of DENND1A (rs9696009) and ERBB4 (rs2178575) with Infertile Polycystic Ovary Syndrome Females in Pakistan
Polycystic Ovary Syndrome (PCOS) is a complex genetic disorder in reproductive-aged women which is associated with comorbidities of reproductive,...
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Factors associated with long-term benzodiazepine and Z-drug use across the lifespan and 5-year temporal trajectories among incident users: a Swedish nationwide register-based study
PurposeDespite being discouraged by guidelines, long-term use of benzodiazepines and related Z-drugs (BZDR) remains frequent in the real-world. An...
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Lymphocyte to High-density Lipoprotein Cholesterol Ratio is Positively Associated with Pre-diabetes, Metabolic Syndrome, and Non-traditional Cardiometabolic Risk Markers: A Cross-sectional Study at Secondary Health Care
High scores of lymphocyte-to-high-density lipoprotein cholesterol ratio (lymphocyte-to-HDL-c) may be a new indicator of inflammation and metabolic...
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Educational level and characteristics of invasive breast cancer: findings from a French prospective cohort
PurposeBreast cancer (BC) characteristics are known to influence patients survival. Social differences have been reported by previous studies for...