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Apoptosis and pyroptosis in the nasal mucosa of Syrian hamster during SARS-CoV-2 infection and reinfection
In SARS-CoV-2 infection, it has been observed that viral replication lasts longer in the nasal mucosa than in the lungs, despite the presence of a...
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Identification of Immune Cells in Murine Olfactory Mucosa
Olfactory immunology is an emerging field in the context of infectious disease and neuroimmunology, yet characterization of immune cells within the... -
Increased CpG methylation at the CDH1 locus in inflamed ileal mucosa of patients with Crohn disease
BackgroundE-cadherin, a major actor of cell adhesion in the intestinal barrier, is encoded by the CDH1 gene associated with susceptibility to Crohn...
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Development of a lip vermilion epithelium reconstruction model using keratinocytes from skin and oral mucosa
Lip vermilion is unique and can be distinguished from the adjacent skin and oral mucosa. However, because of the lack of appropriate evaluation...
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Effects of prophylactic antibiotics administration on barrier properties of intestinal mucosa and mucus from preterm born piglets
Early intervention and short-duration treatments with antibiotics in premature infants are reported to reduce the incidence of necrotizing...
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BMP-2 and IL-1β as Markers of Nasal Mucosa Inflammation in Rhinosinusitis with Nasal Polyps
Rhinosinusitis with nasal polyps is characterized by chronic inflammation and hyperplasia of the nasal mucosa. The key mechanism for polyp formation...
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Environmental enrichment reverses proulcerogenic action of social isolation on the gastric mucosa and positively influences pain sensitivity and work capacity
The aim of the study was to investigate the effects of rat housing conditions—standard conditions, social isolation, environmental enrichment—and the...
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Serotonergic Paracrine Targets in the Intestinal Mucosa
SerotoninSerotonin functionsSerotonergic paracrine targets as a neurotransmitterIntestinal mucosa in the enteric nervous systemEnteric nervous system... -
Transplantation of olfactory mucosa mesenchymal stromal cells repairs spinal cord injury by inducing microglial polarization
Study designAnimal studies
ObjectivesTo evaluate the therapeutic effect of olfactory mucosa mesenchymal stem cell (OM-MSCs) transplantation in mice...
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Diurnal changes in bacterial settlement on the Peyer’s patch and surrounding mucosa in the rat ileum and its effect against the intestinal immune system
Our previous study revealed the diurnal change in the indigenous bacteria settling on the terminal region of the rat ileum. In the present study, we...
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PDE5 inhibitors and gastric mucosa: implications for the management of peptic ulcer disease
Peptic ulcer disease (PUD) continues to be a cause of significant morbidity and mortality worldwide. Almost two-thirds of PUD cases are asymptomatic....
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The orphan MRGPRF receptor is expressed in entero-endocrine cells of the human gut mucosa
In the past years, it has become clear that the family of Mas-related G protein-coupled receptors plays a central role in neuro-immune communication...
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Automated Assessment of the Area of Infiltration by CD8+ Cells in Gastric Carcinoma and Areas of Normal Mucosa as a Significant Prognostic Factor
In 139 patients with verified gastric cancer, the infiltration of the postoperative material with CD8 + cells was analyzed. Automated morphometric...
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Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry
Characterization of inflammation in chronic rhinosinusitis with (CRSwNP) and without nasal polyps (CRSsNP) is an ongoing research process. To...
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The Specifics of Neovascularization of Wound Defects in the Oral Mucosa during Its Regeneration under a Piezoelectric Polymer Membrane
We studied restoration of microvessels in the oral mucosa wound defects under a polymer piezoelectric membrane (group 2) and without it (group 1)....
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Normal gastrointestinal mucosa at biopsy and subsequent cancer risk: nationwide population-based, sibling-controlled cohort study
BackgroundWhile individuals with normal gastrointestinal (GI) mucosa on endoscopy have a lower risk of colorectal cancer, risks of other cancers...
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Enhanced oxidative phosphorylation of IgG plasma cells can contribute to hypoxia in the mucosa of active ulcerative colitis
Mucosal hypoxia is detected in the mucosa of ulcerative colitis (UC), however the mechanism and the cause of hypoxia is not fully understood, while a...
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Long-term intensive endurance exercise training is associated to reduced markers of cellular senescence in the colon mucosa of older adults
Regular endurance exercise training is an effective intervention for the maintenance of metabolic health and the prevention of many age-associated...
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Weissella confusa F213 ameliorated inflammation and maintained intestinal mucosa integrity in chemically induced colitis rats
ObjectiveThis study was performed to investigate the potential effects of Weissella confusa F213 (WCF213) on chemically-induced colitis rats. Twelve...
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Transplantation of Nasal Olfactory Mucosa Mesenchymal Stem Cells Benefits Alzheimer’s Disease
Alzheimer’s disease (AD) is a common neurodegenerative disease that contributes to 60–70% of dementia in elderly people and is currently incurable....