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Detection of the Adulteration of Motor Oil by Laser Induced Fluorescence Spectroscopy and Chemometric Techniques
Petroleum products are the target of fraudulent practices due to their high commercial value. The aim of this study is to provide a new analysis...
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Neuroprotective effect of chia seed oil nanoemulsion against rotenone induced motor impairment and oxidative stress in mice model of Parkinson’s disease
Chia seed oil (CSO) was reported to possess various pharmacological effects, however, its usefulness is restricted due to its inadequate solubility,...
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Anti-inflammatory, anti-apoptotic, and neuroprotective potentials of anethole in Parkinson’s disease-like motor and non-motor symptoms induced by rotenone in rats
Parkinson's disease (PD) is a complex neurological disorder characterized by a combination of motor and non-motor symptoms (NMS). Antioxidant and...
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Neurobehavioral Analysis to Assess Olfactory and Motor Dysfunction in Parkinson’s Disease
Parkinson’s disease (PD) is the second most common neurodegenerative condition, primarily affecting dopaminergic neurons. It is defined by motor...
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Microglial EPOR Contribute to Sevoflurane-induced Developmental Fine Motor Deficits Through Synaptic Pruning in Mice
Clinical researches including the Mayo Anesthesia Safety in Kids (MASK) study have found that children undergoing multiple anesthesia may have a...
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Shark fish oil prevents scopolamine-induced memory impairment in an experimental model
Fish oil has been known for its antioxidant, cardioprotective, anti-inflammatory, and neuroprotective characteristics due to the presence of...
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Sericin alleviates motor dysfunction by modulating inflammation and TrkB/BDNF signaling pathway in the rotenone-induced Parkinson’s disease model
BackgroundParkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of nigrostriatal dopaminergic...
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CBD-oil as a potential solution in case of severe tamoxifen-related side effects
Tamoxifen may lead to bothersome side effects contributing to non-compliance and decreased quality of life. Patients searching for relief are...
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Structural changes in perineuronal nets and their perforating GABAergic synapses precede motor coordination recovery post stroke
BackgroundStroke remains one of the leading causes of long-term disability worldwide, and the development of effective restorative therapies is...
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A comparison of techniques for verifying the accuracy of precision decomposition-derived relationships between motor unit firing rates and recruitment thresholds from surface EMG signals
Approaches for validating motor unit firing times following surface electromyographic (EMG) signal decomposition with the precision decomposition III...
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Alpha-Pinene Alleviates Motor Activity in Animal Model of Huntington’s Disease via Enhancing Antioxidant Capacity
Huntington’s disease (HD) is a progressive, neurodegenerative, and inherited disease. Antioxidants have been shown to be effective in slowing disease...
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In-vivo assessment of wound healing activity of halibut oil cream in rat model of excision wound
This study explores the effects of halibut oil cream on different phases of wound healing and assess its potential as a supplement for promoting...
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X-linked SBMA model mice display relevant non-neurological phenotypes and their expression of mutant androgen receptor protein in motor neurons is not required for neuromuscular disease
X-linked spinal and bulbar muscular atrophy (SBMA; Kennedy's disease) is a rare neuromuscular disorder characterized by adult-onset proximal muscle...
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The aqueous extract of Ulomoides dermestoides larvae counteract motor and cognitive disfunction in a neurotoxic model of Parkinson's disease
Insects are a potential source of novel bioactive compounds with pharmaceutical applications. Our previous study revealed the presence of antioxidant...
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ATH434 Rescues Pre-motor Hyposmia in a Mouse Model of Parkinsonism
Hyposmia is a prevalent prodromal feature of Parkinson’s disease (PD), though the neuropathology that underlies this symptom is poorly understood....
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FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms
BackgroundAstrocytes play a crucial, yet not fully elucidated role in the selective motor neuron pathology in amyotrophic lateral sclerosis (ALS)....
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Knockdown of Astrocytic Monocarboxylate Transporter 4 in the Motor Cortex Leads to Loss of Dendritic Spines and a Deficit in Motor Learning
Monocarboxylate transporters (MCTs) shuttle molecules, including L-lactate, involved in metabolism and cell signaling of the central nervous system....
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Clove volatile oil-loaded nanoemulsion reduces the anxious-like behavior in adult zebrafish
BackgroundClove volatile oil (CVO) and its major compound, eugenol (EUG), have anxiolytic effects, but their clinical use has been impaired due to...
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Study protocol: fish oil supplement in prevention of oxaliplatin-induced peripheral neuropathy in adjuvant colorectal cancer patients – a randomized controlled trial. (OxaNeuro)
BackgroundOxaliplatin-induced peripheral neuropathy (OIPN) in general and painful OIPN in particular is a debilitating late effect that severely...
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Persistent NRG1 Type III Overexpression in Spinal Motor Neurons Has No Therapeutic Effect on ALS-Related Pathology in SOD1G93A Mice
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting upper and lower motor neurons (MNs). Neuregulin-1 (NRG1) is...
