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Molecular Mechanisms of Oncogenesis
Oncogenesis is the process of transformation of normal cells into malignant cells. It is often initiated by a variety of exogenous environmental and...
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Molecular Evolution
Molecular evolution occurs in the genome in the form of substitutions, insertion/deletion, recombination and gene conversion. The principles of...
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Principles Governing Molecular Recognition
No interaction—no information. This principle governs the science of molecular sensing, with the limitation that the interaction should be highly...
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Molecular Immunology How Science Works
This textbook aims to describe in a condensed form the essentials of molecular immunology behind bacterial infections, the microbiome, viral...
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Molecular Mechanisms Underlying Synaptic Tagging and Consolidation
After a synapse undergoes long-term potentiation (LTP), it acquires a newly remodeled molecular and structural organization. This reorganization over...
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Technologies to Study Genetics and Molecular Pathways
Over the last few decades, the study of congenital heart disease (CHD) has benefited from various model systems and the development of molecular...
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Molecular Biology of Arboviruses
This memoir traces the evolving studies on the molecular biology of arboviruses in the Strauss lab from 1969 to 2007. Jim began working with Sindbis...
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Diagnosis of Echinococciasis: Parasitological, Immunological, and Molecular Tools
Echinococcosis is a serious zoonotic disease caused by the larvae of several Echinococcus species forming a hydatid cyst, which can parasitize humans...
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Molecular Tools for Characterizing AMR Pathogens
Antimicrobial resistance in bacterial pathogens is growing at a rapid pace. The problem of AMR has percolated to different sectors. The first and...
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Molecular Landscape of Oral Cancer in Young Adults
AbstractOral cancer (OC) is the most common cancer of the head and neck. Tongue cancer (TC) is the most frequently diagnosed form of OC and is...
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Molecular Tools for Characterizing AMR Pathogens
Antimicrobial resistance in bacterial pathogens is growing at a rapid pace. The problem of AMR has percolated to different sectors. The first and...
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gp120-derived amyloidogenic peptides form amyloid fibrils that increase HIV-1 infectivity
Apart from mediating viral entry, the function of the free HIV-1 envelope protein (gp120) has yet to be elucidated. Our group previously showed that...
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Applications of Molecular Dynamics Simulations in Drug Discovery
In the current drug development process, molecular dynamics (MD) simulations have proven to be very useful. This chapter provides an overview of the...
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Molecular Pathways and Animal Models of Cardiomyopathies
Cardiomyopathies are a heterogeneous group of disorders of the heart muscle that ultimately result in congestive heart failure. Rapid progress in...
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Molecular Biomarkers of Cancer and Their Diagnostic Applications
Cancer, characterized by abnormal cell growth, remains a significant global health concern. The intricate interplay of genetic, epigenetic, and...
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TAPVR: Molecular Pathways and Animal Models
The venous pole of the heart where the pulmonary veinsPulmonaryvein will develop encompasses the sinus venosus and the atrium. In the fourth week of...
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Preparation a Recombinant Form of Pneumolysin Protein from Streptococcus pneumoniae
A recombinant form of pneumolysin from Streptococcus pneumoniae was obtained. By using Vector NTI Advance 11.0 bioinformatic analysis software,...
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Molecular Basis of Malaria Pathogenesis
Blood stage is the most important period for parasite growth, development, and pathogenesis. Studying the transcriptional regulatory mechanism of key...
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Molecular Biotechnology: From DNA Sequence to Therapeutic Protein
Therapeutic proteins have become a valuable addition to the repertoire of drugs to treat patients with severe diseases. Therapeutic proteins differ...