Search
Search Results
-
DNA Methylation as a Biomarker and Application to Aluminum: ADRB2 5′-Untranslated Region (5′-UTR) Methylation Level
Environmental heavy metal exposure might be considered as a contributor to childhood asthma development and its levels of control. Moreover, heavy...
-
DNA Methylation
In this chapter, the best-understood epigenetic mark, cytosine methylation of genomic DNA, will be introduced. DNA methylation is performed by DNA...
-
DNA Methylation Analysis
DNA methylation of promoter CpG islands silences their downstream genes, and enhancer methylation can be associated with decreased or increased gene...
-
SOCS1 methylation level is associated with prognosis in patients with acute-on-chronic hepatitis B liver failure
BackgroundGlucocorticoids could greatly improve the prognosis of patients with acute-on-chronic hepatitis B liver failure (ACHBLF). Suppressor of...
-
Identifying primary and secondary MLH1 epimutation carriers displaying low-level constitutional MLH1 methylation using droplet digital PCR and genome-wide DNA methylation profiling of colorectal cancers
BackgroundMLH1 epimutation is characterised by constitutional monoallelic MLH1 promoter hypermethylation, which can cause colorectal cancer (CRC)....
-
Association between acetaminophen metabolites and CYP2E1 DNA methylation level in neonate cord blood in the Boston Birth Cohort
BackgroundAcetaminophen is a commonly used medication by pregnant women and is known to cross the placenta. However, little is known about the...
-
Changes in the Level of Methylation of a Group of microRNA Genes as a Factor in the Development and Progression of Non-Small Cell Lung Cancer
We studied changes in the level of methylation of a number of microRNA genes hypermethylated in non-small cell lung cancer and its histological...
-
DNA Methylation as a Biomarker and Application to Aluminum: ADRB2 5′-Untranslated Region (5′-UTR) Methylation Level
Environmental heavy metal exposure might be considered as a contributor to childhood asthma development and its levels of control. Moreover, heavy...
-
The association between DNA methylation and human height and a prospective model of DNA methylation-based height prediction
As a vital anthropometric characteristic, human height information not only helps to understand overall developmental status and genetic risk...
-
Maternal obesity alters methylation level of cytosine in CpG island for epigenetic inheritance in fetal umbilical cord blood
BackgroundOver the past few decades, global maternal obesity prevalence has rapidly increased. This condition may induce long-lasting...
-
Aberrant DNA Methylation Profile of Dickkopf-1 in Ankylosing Spondylitis
In recent years, the impact of methylation modifications on Dickkopf-1 (DKK1) in relation to ankylosing spondylitis (AS) has remained elusive. Our...
-
DNA Methylation in Experimental Ischemic Brain Injury
The enrichment of angioneurology with fundamental achievements is leading to an understanding of new important aspects of the pathogenesis of...
-
Abnormal DNA methylation analysis of leucine-rich glioma-inactivated 1 antibody encephalitis reveals novel methylation-driven genes related to prognostic and clinical features
BackgroundAberrant DNA methylation occurs commonly during pathogenesis of neuroimmunological diseases and is of clinical value in various...
-
DNA Methylation and Epigenetic Aging Biomarkers in Huntington’s Disease
DNA methylation is an epigenetic modification that plays critical roles in several important processes, including regulation of transcription,...
-
Methylation of the Retrotransposon LINE-1 Subfamilies in Chorionic Villi of Miscarriages
AbstractMiscarriage is potentially associated with abnormal epigenetic regulation of genes responsible for the development of the embryo and...
-
Degradation of methylation signals in cryopreserved DNA
BackgroundBlood-based DNA methylation has shown great promise as a biomarker in a wide variety of diseases. Studies of DNA methylation in blood often...
-
DNA Methylation in Aortic Aneurysms of Different Localizations
Abstract—Aortic aneurysm (AA) is a life-threatening condition, and aortic rupture that is the complication of AA in the absence of emergency surgery...
-
Association of methylation level and transcript level in TRAF5 gene with ankylosing spondylitis: a case-control study
To explore the association between methylation level and transcript level of TNF receptor-associated factor 5 (TRAF5) gene with ankylosing...
-
Methylation of serotonin regulating genes in cord blood cells: association with maternal metabolic parameters and correlation with methylation in peripheral blood cells during childhood and adolescence
BackgroundSerotonin (5-hydroxytryptamine, 5-HT) signaling is involved in neurodevelopment, mood regulation, energy metabolism, and other...
-
Nucleic acid and protein methylation modification in renal diseases
Although great efforts have been made to elucidate the pathological mechanisms of renal diseases and potential prevention and treatment targets that...
