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Crucial Metabolic Networks: Cancer Progression
The study of metabolic networks in cancer cells is essential for understanding the fundamental properties of living systems and how metabolic...
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Metabolic Rewiring in Cancer: Understanding the Complexity of Metabolic Networks
Cancer is characterized by uncontrolled cell growth and survival, which entails the reprogramming of metabolic pathways to generate energy and...
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Crucial Metabolic Networks: Cancer Progression
The study of metabolic networks in cancer cells is essential for understanding the fundamental properties of living systems and how metabolic...
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Metabolic Networks in Parkinson’s Disease
Our understanding of Parkinson’s disease (PD) has progressed from a focal disorder primarily of the basal ganglia to a more widespread “network”...
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Metabolic Rewiring in Cancer: Understanding the Complexity of Metabolic Networks
Cancer is characterized by uncontrolled cell growth and survival, which entails the reprogramming of metabolic pathways to generate energy and...
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Cross-modality comparison between structural and metabolic networks in individual brain based on the Jensen-Shannon divergence method: a healthy Chinese population study
The study aimed to investigate the consistency and diversity between metabolic and structural brain networks at individual level constructed with...
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Identification of Metabolic Syndrome-Related miRNA–mRNA Regulatory Networks and Key Genes Based on Bioinformatics Analysis
Metabolic syndrome, which affects approximately one-quarter of the world’s population, is a combination of multiple traits and is associated with...
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Visualising Metabolic Pathways and Networks: Past, Present, Future
Visualisations of metabolites and metabolic pathways have been used since the early years of research in biology, and pathway maps have become very...
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METABOLIC: high-throughput profiling of microbial genomes for functional traits, metabolism, biogeochemistry, and community-scale functional networks
BackgroundAdvances in microbiome science are being driven in large part due to our ability to study and infer microbial ecology from genomes...
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Metabolic Reprogramming As a Prostate Cancer Hallmark
Arising from a disruption of regular biological circuits and control mechanisms, cancer exhibits a remarkable inter- and intra-type heterogeneity, an...
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The roles and molecular mechanisms of non-coding RNA in cancer metabolic reprogramming
One of the key features of cancer is energy metabolic reprogramming which is tightly related to cancer proliferation, invasion, metastasis, and...
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Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment
Oncogenic mutations in KRAS drive common metabolic programmes that facilitate tumour survival, growth and immune evasion in colorectal carcinoma,...
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Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia
Acute myeloid leukemia (AML) is a heterogeneous disease characterized by genomic aberrations in oncogenes, cytogenetic abnormalities, and an aberrant...
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Depletion and activation of microglia impact metabolic connectivity of the mouse brain
AimWe aimed to investigate the impact of microglial activity and microglial FDG uptake on metabolic connectivity, since microglial activation states...
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Heart Disease and the Metabolic Syndrome
In this chapter, we will link three important risk factors for heart disease: hypertension, atherosclerosis and dyslipidemia. Chronically elevated...
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Metabolic heterogeneity affects trastuzumab response and survival in HER2-positive advanced gastric cancer
BackgroundTrastuzumab is the only first-line treatment targeted against the human epidermal growth factor receptor 2 (HER2) approved for patients...
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FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
The escalating obesity epidemic and aging population have propelled metabolic dysfunction-associated steatohepatitis (MASH) to the forefront of...
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Sex-Gender-Based Differences in Metabolic Diseases
Sexual dimorphism creates different biological and cellular activities and selective regulation mechanisms in males and females, thus generating...
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Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis
A novel rheumatoid arthritis (RA) synovial fluid protein, Syntenin-1, and its receptor, Syndecan-1 (SDC-1), are colocalized on RA synovial tissue...
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Dichotomous metabolic networks govern human ILC2 proliferation and function
Group 2 innate lymphoid cells (ILC2s) represent innate homologs of type 2 helper T cells (T H 2) that participate in immune defense and tissue...
