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  1. Mesenchymal Stem Cells

    Tumor microenvironment (TME) is a complex network with a heterogeneous ensemble of cancer cells, mesenchymal stromal/stem cells (MSCs), inflammatory...
    Living reference work entry 2022
  2. Mesenchymal Stem Cells

    Tumor microenvironment (TME) is a complex network with a heterogeneous ensemble of cancer cells, mesenchymal stromal/stem cells (MSCs), inflammatory...
    Reference work entry 2022
  3. Exosomes Derived from Mesenchymal Stem Cells: Therapeutic Opportunities for Spinal Cord Injury

    Spinal cord injury (SCI) is a serious neurological condition comprising primary and secondary injury and causing severe neurological impairments. The...

    Article 01 April 2024
  4. Role of Mesenchymal Stem/Stromal Cells in Cancer Development

    The tumor stroma is now recognized as a key factor in cancer development, as is the need for a deeper understanding of the underlying mechanisms for...
    Marta E. Castro-Manrreza, Ignacio Martínez in Cancer Research: An Interdisciplinary Approach
    Chapter 2023
  5. Immunomodulatory properties of mesenchymal stem cells/dental stem cells and their therapeutic applications

    Mesenchymal stem/stromal cells (MSCs) are widely distributed in the body and play essential roles in tissue regeneration and homeostasis. MSCs can be...

    Peishan Li, Qianmin Ou, ... Changshun Shao in Cellular & Molecular Immunology
    Article Open access 27 March 2023
  6. The therapeutic effect of mesenchymal stem cells in diabetic kidney disease

    Abstract

    Diabetes mellitus (DM) often causes chronic kidney damage despite best medical practices. Diabetic kidney disease (DKD) arises from a complex...

    Umm E. Habiba, Nasar Khan, ... Amna Umer in Journal of Molecular Medicine
    Article Open access 29 February 2024
  7. Efficacy of Mesenchymal Stem Cells Therapy in Parasitic Infections: Are Anti-parasitic Drugs Combined with MSCs More Effective?

    Purpose

    Mesenchymal stem cells (MSCs) are mesodermal-origin postnatal stem cells that are able to self-renew and differentiate into several cell...

    Mehdi Kian, Somayeh Mirzavand, ... Fatemeh Nasri in Acta Parasitologica
    Article 25 October 2022
  8. Mesenchymal Stem Cells and their Applications against Neurodegenerative Disorders

    Intense research has tremendously increased our knowledge about molecular and cellular mechanisms of neuronal pathogenesis and has yielded new...
    Chapter 2023
  9. Mesenchymal stem cells as therapeutic vehicles for glioma

    Glioma is a disease with a poor prognosis despite the availability of multimodality treatments, and the development of novel therapies is urgently...

    Tomoya Oishi, Shinichiro Koizumi, Kazuhiko Kurozumi in Cancer Gene Therapy
    Article 23 April 2024
  10. Mesenchymal Stem Cell Engineering

    Mesenchymal stem cells (MSC) are multipotent stem cells that display the capacity to generate the tissue in which they reside. MSC have been used as...
    Shuang Liu in Rheumatoid Arthritis
    Protocol 2024
  11. Autophagy in Mesenchymal Stem Cell-Based Therapy

    Mesenchymal stem cellsMesenchymal stem cells (MSC)" (MSCs) are adult stem cells which are, due to their huge differentiation potential, potent...
    Carl Randall Harrell, Dragica Pavlovic, Vladislav Volarevic in Autophagy in Stem Cell Maintenance and Differentiation
    Chapter 2023
  12. Potential role of mesenchymal stem cells in T cell aging

    Immunosenescence occurs with progressive age. T cell aging is manifested by immunodeficiency and inflammation. The main mechanisms are thymic...

    **anmei Zhong, Jie Chen, ... Zhangang **ao in Journal of Molecular Medicine
    Article 26 September 2023
  13. Revisiting the role of mesenchymal stem cells in tuberculosis and other infectious diseases

    Mesenchymal stem cells (MSCs) play diverse roles ranging from regeneration and wound healing to immune signaling. Recent investigations have...

    Annu Devi, Isha Pahuja, ... Gobardhan Das in Cellular & Molecular Immunology
    Article Open access 12 May 2023
  14. Novel perspective in transplantation therapy of mesenchymal stem cells: targeting the ferroptosis pathway

    Ex vivo culture-amplified mesenchymal stem cells (MSCs) have been studied because of their capacity for healing tissue injury. MSC transplantation is...

    Yuzhu Xu, Pan Fan, ... Yuntao Wang in Journal of Zhejiang University-SCIENCE B
    Article 17 February 2023
  15. Challenges of mesenchymal stem cells in the clinical treatment of COVID-19

    The 2019 coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought an enormous public health...

    Lu** Li, **aoshuang Zhang, ... Hongwu Du in Cell and Tissue Research
    Article 21 March 2024
  16. Priming and Combined Strategies for the Application of Mesenchymal Stem Cells in Ischemic Stroke: A Promising Approach

    Ischemic stroke (IS) is a leading cause of death and disability worldwide. Tissue plasminogen activator (tPA) administration and mechanical...

    Hao Tian, Feng Tian, ... Cungen Ma in Molecular Neurobiology
    Article 17 February 2024
  17. Therapeutic and immunomodulatory potentials of mesenchymal stromal/stem cells and immune checkpoints related molecules

    Mesenchymal stromal/stem cells (MSCs) are used in many studies due to their therapeutic potential, including their differentiative ability and...

    Ali Hazrati, Kosar Malekpour, ... Seyed Mahmoud Hashemi in Biomarker Research
    Article Open access 21 March 2024
  18. Development of Mesenchymal Stem Cells Therapy for the Treatment of Polyglutamine SCA: From Bench to Bedside

    This chapter focuses on the clinical application of mesenchymal stem cells (MSCs) for the treatment of spinocerebellar ataxia (SCA). SCA is a...
    Chih-Yuan Ho, Hsiu-Yu Lai, ... Bing-wen Soong in Trials for Cerebellar Ataxias
    Chapter 2023
  19. Exosomes derived from hypoxia-preconditioned mesenchymal stem cells (hypoMSCs-Exo): advantages in disease treatment

    Mesenchymal stem cells (MSCs)-based therapy has been reported to be a potential approach to treat various diseases and the paracrine role might be...

    Jia Dong, Bin Wu, Weidong Tian in Cell and Tissue Research
    Article 13 February 2023
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