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Mesenchymal Stem Cells
Tumor microenvironment (TME) is a complex network with a heterogeneous ensemble of cancer cells, mesenchymal stromal/stem cells (MSCs), inflammatory... -
Mesenchymal Stem Cells
Tumor microenvironment (TME) is a complex network with a heterogeneous ensemble of cancer cells, mesenchymal stromal/stem cells (MSCs), inflammatory... -
Exosomes Derived from Mesenchymal Stem Cells: Therapeutic Opportunities for Spinal Cord Injury
Spinal cord injury (SCI) is a serious neurological condition comprising primary and secondary injury and causing severe neurological impairments. The...
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Role of Mesenchymal Stem/Stromal Cells in Cancer Development
The tumor stroma is now recognized as a key factor in cancer development, as is the need for a deeper understanding of the underlying mechanisms for... -
Immunomodulatory properties of mesenchymal stem cells/dental stem cells and their therapeutic applications
Mesenchymal stem/stromal cells (MSCs) are widely distributed in the body and play essential roles in tissue regeneration and homeostasis. MSCs can be...
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The therapeutic effect of mesenchymal stem cells in diabetic kidney disease
AbstractDiabetes mellitus (DM) often causes chronic kidney damage despite best medical practices. Diabetic kidney disease (DKD) arises from a complex...
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Efficacy of Mesenchymal Stem Cells Therapy in Parasitic Infections: Are Anti-parasitic Drugs Combined with MSCs More Effective?
PurposeMesenchymal stem cells (MSCs) are mesodermal-origin postnatal stem cells that are able to self-renew and differentiate into several cell...
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Mesenchymal Stem Cells and their Applications against Neurodegenerative Disorders
Intense research has tremendously increased our knowledge about molecular and cellular mechanisms of neuronal pathogenesis and has yielded new... -
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Mesenchymal stem cells as therapeutic vehicles for glioma
Glioma is a disease with a poor prognosis despite the availability of multimodality treatments, and the development of novel therapies is urgently...
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Mesenchymal Stem Cell Engineering
Mesenchymal stem cells (MSC) are multipotent stem cells that display the capacity to generate the tissue in which they reside. MSC have been used as... -
Autophagy in Mesenchymal Stem Cell-Based Therapy
Mesenchymal stem cellsMesenchymal stem cells (MSC)" (MSCs) are adult stem cells which are, due to their huge differentiation potential, potent... -
Potential role of mesenchymal stem cells in T cell aging
Immunosenescence occurs with progressive age. T cell aging is manifested by immunodeficiency and inflammation. The main mechanisms are thymic...
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Revisiting the role of mesenchymal stem cells in tuberculosis and other infectious diseases
Mesenchymal stem cells (MSCs) play diverse roles ranging from regeneration and wound healing to immune signaling. Recent investigations have...
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Novel perspective in transplantation therapy of mesenchymal stem cells: targeting the ferroptosis pathway
Ex vivo culture-amplified mesenchymal stem cells (MSCs) have been studied because of their capacity for healing tissue injury. MSC transplantation is...
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Challenges of mesenchymal stem cells in the clinical treatment of COVID-19
The 2019 coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought an enormous public health...
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Priming and Combined Strategies for the Application of Mesenchymal Stem Cells in Ischemic Stroke: A Promising Approach
Ischemic stroke (IS) is a leading cause of death and disability worldwide. Tissue plasminogen activator (tPA) administration and mechanical...
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Therapeutic and immunomodulatory potentials of mesenchymal stromal/stem cells and immune checkpoints related molecules
Mesenchymal stromal/stem cells (MSCs) are used in many studies due to their therapeutic potential, including their differentiative ability and...
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Development of Mesenchymal Stem Cells Therapy for the Treatment of Polyglutamine SCA: From Bench to Bedside
This chapter focuses on the clinical application of mesenchymal stem cells (MSCs) for the treatment of spinocerebellar ataxia (SCA). SCA is a... -
Exosomes derived from hypoxia-preconditioned mesenchymal stem cells (hypoMSCs-Exo): advantages in disease treatment
Mesenchymal stem cells (MSCs)-based therapy has been reported to be a potential approach to treat various diseases and the paracrine role might be...