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Evidence for RA-dependent meiosis onset in a turtle embryo
Meiotic entry is one of the earliest sex determination events of the germ cell in higher vertebrates. Although advances in meiosis onset have been...
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Bi-allelic MEI1 variants cause meiosis arrest and non-obstructive azoospermia
Non-obstructive azoospermia (NOA) is characterized by the failure of sperm production due to testicular disorders and represents the most severe form...
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Meiosis at three loci in autotetraploids: Probabilities of gamete modes and genotypes without and with preferential cross-over formation
A long-standing goal in the field of polyploid biology has been the derivation of mathematical models of gamete mode formation. These models form the...
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Differential expression of meiosis and homologous recombination-related genes in the life cycle of Trypanosoma cruzi
Trypanosoma cruzi has a complex life cycle consisting of four morphological and distinct biological stages. Although some authors suggest that T. cruzi ...
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Fragile, unfaithful and persistent Ys—on how meiosis can shape sex chromosome evolution
Sex-linked inheritance is a stark exception to Mendel’s Laws of Heredity. Here we discuss how the evolution of heteromorphic sex chromosomes (mainly...
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Detection of DSBs in C. elegans Meiosis
Meiosis is a specialized reductional cell division responsible for the formation of gametes and the generation of genetic diversity. A fundamental...
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Cytological Analysis and Fine Map** of paa1 (Post-meiosis Abnormal Anther 1) Mutant with Abnormal Tapetum and Microspore Development
To further understand the molecular mechanism for rice male reproduction, a rice male sterile mutant paa1 was screened from the rice mutant library...
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Comparison of Metabolic Profiling of Arabidopsis Inflorescences Between Landsberg erecta and Columbia, and Meiosis-Defective Mutants by 1H-NMR Spectroscopy
With the rapid development of omics technologies during the last several decades, genomics, transcriptomics, and proteomics have been extensively...
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Varietal variation and chromosome behaviour during meiosis in Solanum tuberosum
Naturally occurring autopolyploid species, such as the autotetraploid potato Solanum tuberosum , face a variety of challenges during meiosis. These...
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Methods of Detection and Mechanisms of Origin of Complex Structural Genome Variations
Based on classical karyoty**, structural genome variations (SVs) have generally been considered to be either “simple” (with one or two breakpoints)...
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PPP2R1A silencing suppresses LUAD progression by sensitizing cells to nelfinavir-induced apoptosis and pyroptosis
Lung adenocarcinoma is a major public health problem with the low 5-year survival rate (15%) among cancers. Aberrant alterations of meiotic genes,...
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Transcriptomics and the origin of obligate parthenogenesis
Despite the presence of obligately parthenogenetic (OP) lineages derived from sexual ancestors in diverse phylogenetic groups, the genetic mechanisms...
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Search for Candidate Genes for Mutations Disrupting Synaptonemal Complex Formation in the Sequenced Genome of Rye Secale cereale
The formation of a synaptonemal complex between homologous chromosomes during prophase I of meiosis is of great importance for the normal course of...
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Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis
BackgroundMammalian gonadal development is crucial for fertility. Sexual differentiation, meiosis and gametogenesis are critical events in the...
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Divergence and conservation of the meiotic recombination machinery
Sexually reproducing eukaryotes use recombination between homologous chromosomes to promote chromosome segregation during meiosis. Meiotic...
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Epigenetic regulator Cfp1 safeguards male meiotic progression by regulating meiotic gene expression
Meiosis occurs specifically in germ cells to produce sperm and oocytes that are competent for sexual reproduction. Multiple factors are required for...
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NECL2 regulates blood–testis barrier dynamics in mouse testes
The adhesion protein nectin-like molecule 2 (NECL2) is involved in spermatogenesis and participates in the connections between Sertoli cells and germ...
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Is There a Relationship Between Mating and Pathogenesis in Two Human Fungal Pathogens, Candida albicans and Candida glabrata?
Purpose of ReviewHuman fungal pathogens are rapidly increasing in incidence and readily able to evade the host immune responses. Our ability to study...
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Loss of SUN1 function in spermatocytes disrupts the attachment of telomeres to the nuclear envelope and contributes to non-obstructive azoospermia in humans
One of the most severe forms of infertility in humans, caused by gametogenic failure, is non-obstructive azoospermia (NOA). Approximately, 20–30% of...
