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Matrix Metalloproteinase-9 and Its Involvement in Parkinson’s Disease
AbstractParkinson’s disease is a neurodegenerative, multifactorial movement disorder. Several lines of evidence suggest the involvement of oxidative...
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The Role of Serum Matrix Metalloproteinase-9 as a Predictor of Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage
Delayed cerebral ischemia (DCI) is one of the major causes of a poor neurological outcome following aneurysmal subarachnoid hemorrhage (aSAH)....
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Potential genetic polymorphism of matrix metalloproteinase (MMP)-9 in Iranian migraine patients with Toxoplasma gondii infection
Toxoplasma gondii is an intracellular protozoan parasite that causes neuroinflammation in the brain and a constant need for peripheral leukocyte...
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The expression of matrix metalloproteinase 2, 9 and 11 in Ethiopian breast cancer patients
IntroductionMatrix metalloproteinases (MMPs) play a pathophysiological role in cancer initiation and progression. Numerous studies have examined an...
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MiR-30c-1-3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms
AbstractAbdominal aortic aneurysm (AAA) can be fatal if ruptured, but there is no predictive biomarker. Our aim was to evaluate the prognostic...
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Evaluation of matrix metalloproteinase-9 plasma levels in untreated new Relapsing–remitting multiple sclerosis patients and their first-degree family
Matrix metalloproteinase, especially Matrix metalloproteinase-9 (MMP-9) has vital roles in the disruption of blood barrier, neuroinflammation and...
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Albumin alleviated esketamine-induced neuronal apoptosis of rat retina through downregulation of Zn2+-dependent matrix metalloproteinase 9 during the early development
AimsEsketamine upregulates Zn 2+ -dependent matrix metalloproteinase 9 (MMP9) and increases the neuronal apoptosis in retinal ganglion cell layer...
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Tumor necrosis factor-α and matrix metalloproteinase-9 cooperatively exacerbate neurovascular degeneration in the neonatal rat retina
Matrix metalloproteinases (MMPs) and tumor necrosis factor (TNF)-α contribute to the pathogenesis of several ocular diseases. Previous studies have...
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Resistance training modifies of serum levels of matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases in multiple sclerosis women - a randomized controlled trail
The objectives of the present study was to investigate the effects of resistance training (RT) on serum levels of controlling blood-brain barrier...
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Association of Matrix Metalloproteinase-2 (MMP-2) and MMP-9 Promoter Polymorphisms, Their Serum Levels, and Activities with Coronary Artery Calcification (CAC) in an Iranian Population
The serum levels and activity of matrix metalloproteinases (MMPs) are associated with the risk of coronary artery calcification (CAC). We sought to...
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Matrix Metalloproteinase-9 Overexpression Regulates Hippocampal Synaptic Plasticity and Decreases Alcohol Consumption and Preference in Mice
Brain matrix metalloproteinases (MMPs) have been recently implicated in alcohol addiction; however, the molecular mechanisms remain poorly...
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Disturbed Matrix Metalloproteinases Activity in Age-Related Macular Degeneration
Matrix metalloproteinases (MMPs) are a tightly regulated family of proteolytic enzymes that break down extracellular matrix (ECM) and basement...
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Analysis of Matrix Metalloproteinase Activity and Inhibition in Cancer Spheroids
The utilization of tumor spheroids and organoids has greatly facilitated mechanistic understanding of tumor growth and invasion and lead to more...
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The Link Between Matrix Metalloproteinases and Alzheimer’s Disease Pathophysiology
Alzheimer’s disease (AD) is a major contributor to dementia and the most common neurodegenerative disorder. In AD pathophysiology, matrix...
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Rottlerin, a natural polyphenol compound, inhibits upregulation of matrix metalloproteinase-9 and brain astrocytic migration by reducing PKC-δ-dependent ROS signal
BackgroundUpregulation of matrix metalloproteinase-9 (MMP-9) has been indicated as one of the inflammatory biomarkers. In the central nervous system...
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Matrix Metalloproteinases (MMPs) in Cancer Immunotherapy
Matrix metalloproteinases (MMPs) are the zinc-dependent endopeptidases that mediate the degradation of the extracellular matrix (ECM) constituents...
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Matrix Metalloproteinases (MMPs) in Cancer Immunotherapy
Matrix metalloproteinases (MMPs) are the zinc-dependent endopeptidases that mediate the degradation of the extracellular matrix (ECM) constituents...
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Crosstalk Between Matrix Metalloproteinases and Their Inducer EMMPRIN/CD147: a Promising Therapeutic Target for Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is characterized by the disruption of cerebrovascular integrity, resulting in hematoma enlargement, edema formation,...
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Sex-specific associations of matrix metalloproteinases in Alzheimer’s disease
IntroductionAlzheimer’s disease (AD) can be characterised in vivo by biomarkers reflecting amyloid-β (Aβ) and tau pathology. However, there is a need...
