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Showing 1-20 of 2,469 results
  1. Poor clinical guideline adherence and inappropriate testing for incident lower urinary tract symptoms associated with benign prostatic hyperplasia

    Background

    The American Urological Association makes recommendations for evaluation and testing for lower urinary tract symptoms associated with...

    Charles Welliver, Lydia Feinstein, ... Kevin McVary in Prostate Cancer and Prostatic Diseases
    Article 20 September 2021
  2. Delineating three-dimensional behavior of uveal melanoma cells under anchorage independent or dependent conditions

    Background

    Although rare, uveal melanoma (UM) is a life-threatening malignancy. Understanding its biology is necessary to improve disease outcome....

    Alicia A. Goyeneche, Jade M. E. Lasiste, ... Miguel N. Burnier Jr. in Cancer Cell International
    Article Open access 23 May 2024
  3. Real-World Evidence of the Top 100 Prescribed Drugs in the USA and Their Potential for Drug Interactions with Nirmatrelvir; Ritonavir

    Nirmatrelvir (coadministered with ritonavir as PAXLOVID TM ) reduces the risk of COVID-19-related hospitalizations and all-cause death in individuals...

    Jacqueline Gerhart, Florin Draica, ... Bharat D. Damle in The AAPS Journal
    Article Open access 20 July 2023
  4. CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors

    CD4 + T cells can "help” or "license” conventional type 1 dendritic cells (cDC1s) to induce CD8 + cytotoxic T lymphocyte (CTL) anticancer responses, as...

    **n Lei, Daniël C. de Groot, ... Yanling **ao in Cellular & Molecular Immunology
    Article Open access 21 February 2024
  5. Artificial Intelligence in Intensive Care Medicine: Toward a ChatGPT/GPT-4 Way?

    Although intensive care medicine (ICM) is a relatively young discipline, it has rapidly developed into a full-fledged and highly specialized...

    Yanqiu Lu, Haiyang Wu, ... Kunming Cheng in Annals of Biomedical Engineering
    Article 13 May 2023
  6. Usefulness of monitoring circulating tumor cells as a therapeutic biomarker in melanoma with BRAF mutation

    Background

    While molecularly targeted therapies and immune checkpoint inhibitors have improved the prognosis of advanced melanoma, biomarkers are...

    Yukiko Kiniwa, Kenta Nakamura, ... Ryuhei Okuyama in BMC Cancer
    Article Open access 17 March 2021
  7. Molecular mimicry and cancer vaccine development

    Background

    The development of cancer immunotherapeutic strategies relies on the identification and validation of optimal target tumor antigens, which...

    Maria Tagliamonte, Beatrice Cavalluzzo, ... Luigi Buonaguro in Molecular Cancer
    Article Open access 26 April 2023
  8. Influence of the trajectory of the urine output for 24 h on the occurrence of AKI in patients with sepsis in intensive care unit

    Background

    Sepsis-associated acute kidney injury (S-AKI) is a common and life-threatening complication in hospitalized and critically ill patients....

    Luming Zhang, Fengshuo Xu, ... Jun Lyu in Journal of Translational Medicine
    Article Open access 20 December 2021
  9. Euterpe oleracea Mart. (Açaí) attenuates experimental colitis in rats: involvement of TLR4/COX-2/NF-ĸB

    Euterpe oleracea Mart., commonly known as açaí, has been demonstrated to exhibit significantly antioxidant and inflammatory activities in...

    Carlos Eduardo da Silva Monteiro, Humberto Barbosa da Costa Filho, ... André Luiz dos Reis Barbosa in Inflammopharmacology
    Article 29 September 2020
  10. TIM-3 regulates the proliferation by BDNF-mediated PI3K/AKT axis in the process of endometriosis

    Background

    T cell immunoglobulin and mucin domain-containing molecule-3 (TIM-3) initially discovered on the surface of Th1 cells, negatively regulates...

    Wei Tian, Min Liu, ... Mingjiang Li in Molecular Medicine
    Article Open access 19 December 2023
  11. Traditional medicinal plants used in the treatment of viral diseases

    Nowadays, theoretical chemistry has experienced a great advance in the search for drugs for the treatment of various human and animal pathologies....

    Joachim Djimon Gbenou, Placide Mahougnan Toklo, ... Eléonore Chikani Yayi in Advances in Traditional Medicine
    Article 02 July 2023
  12. Extracellular Vesicles in Cancer Immunotherapy

    Extracellular vesicles (EVs) are nanoscale vesicles that contain a repertoire of molecules representing the cell of origin. Cancer cell-derived EVs...
    **urong Ke, Wijnand Helfrich, Hao Zhang in Extracellular Vesicles
    Chapter 2024
  13. Açaí (Euterpe oleracea Mart.) as a Potential Anti-neuroinflammatory Agent: NLRP3 Priming and Activating Signal Pathway Modulation

    Neurological disorders have been demonstrated to be associated with mitochondrial dysfunction. This impairment may lead to oxidative stress and...

    Francine Carla Cadoná, Diulie Valente de Souza, ... Alencar Kolinski Machado in Molecular Neurobiology
    Article 22 May 2021
  14. Identification of BACH1-IT2-miR-4786-Siglec-15 immune suppressive axis in bladder cancer

    The sialic acid binding Ig like lectin 15 (Siglec-15) was previously identified as tumor immune suppressor gene in some human cancers with elusive...

    **ngzhi Li, Ziji Liang, ... Caiyan Liao in BMC Cancer
    Article Open access 11 March 2024
  15. Development of Immune Cell Therapy Using T Cells Generated from Pluripotent Stem Cells

    In the field of cancer immunotherapy, the effectiveness of a method in which patient-derived T cells are genetically modified ex vivo and...
    Hiroshi Kawamoto, Kyoko Masuda, Seiji Nagano in Basic Immunology and Its Clinical Application
    Chapter 2024
  16. MART-1

    MART-1 (melanoma antigen recognized by T cells) is also known as Melan-A. It has gained wide acceptance as an immunohistochemical marker to diagnose...
    Brendan D. Curti in Cancer Therapeutic Targets
    Reference work entry 2017
  17. Navigating the Landscape of MANF Research: A Scientometric Journey with CiteSpace Analysis

    This study employs bibliometric analysis through CiteSpace to comprehensively evaluate the status and trends of MANF (mesencephalic astrocyte-derived...

    Caixia Zhang, Mi Zhang, ... **anwei Zhang in Cellular and Molecular Neurobiology
    Article Open access 26 September 2023
  18. Animal Models for Cancer Immunology

    Purpose of Review

    This review discusses the characteristics of different in vivo experimental immunologic models for the development of...

    Selen Kum Özşengezer, Zekiye S. Altun in Current Molecular Biology Reports
    Article 20 October 2023
  19. Melanocytes in regenerative medicine applications and disease modeling

    Melanocytes are dendritic cells localized in skin, eyes, hair follicles, ears, heart and central nervous system. They are characterized by the...

    Kelly Coutant, Brice Magne, ... Solange Landreville in Journal of Translational Medicine
    Article Open access 08 April 2024
  20. T cell receptor therapeutics: immunological targeting of the intracellular cancer proteome

    The T cell receptor (TCR) complex is a naturally occurring antigen sensor that detects, amplifies and coordinates cellular immune responses to...

    Christopher A. Klebanoff, Smita S. Chandran, ... Antoni Ribas in Nature Reviews Drug Discovery
    Article 27 October 2023
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