Search
Search Results
-
Magnetic procedure for sentinel lymph node detection and evaluation of metastases: design and rationale of the Lowmag trial
BackgroundPrimary tumour biology and axillary lymph node status are key prognostic factors in breast cancer treatment. The LowMag trial introduced a...
-
Nectin-4 is frequently expressed in primary salivary gland cancer and corresponding lymph node metastases and represents an important treatment-related biomarker
Many locally advanced and metastatic salivary gland carcinomas (SGC) lack therapeutic targets. Enfortumab vedotin , an antibody–drug conjugate binding...
-
Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1
BackgroundExtracellular vesicles (EVs) have been revealed to facilitate the development of oral squamous cavity cell carcinoma (OCSCC), while its...
-
Comparison of the distribution of lymph node metastases compared to healthy lymph nodes in breast cancer
BackgroundCurrent literature lacks a comparison of lymph node metastases and non-pathological lymph nodes distribution in breast cancer patients. The...
-
Acetone compression improves lymph node yield and metastasis detection in colorectal cancer
Lymph node status is one of the most important prognostic factors in colorectal cancer, and accurate pathological nodal staging and detection of...
-
Clinical relevance of biomarker discordance between primary breast cancers and synchronous axillary lymph node metastases
Clinical decision-making for patients with breast cancer (BC) is still primarily based on biomarker characteristics of the primary tumor, together...
-
Ultrasonography and clinicopathological features of breast cancer in predicting axillary lymph node metastases
BackgroundEarly identification of axillary lymph node metastasis (ALNM) in breast cancer (BC) is still a clinical difficulty. There is still no good...
-
Diagnostic performance of Node Reporting and Data System (Node-RADS) for assessing mesorectal lymph node in rectal cancer by CT
BackgroundTo compare the diagnostic performance of the Node-RADS scoring system and lymph node (LN) size in preoperative LN assessment for rectal...
-
Regional Onco-Sphere: Lymph Node Metastasis
During cancer metastasis, cancer cells spread by dissemination into nearby normal tissue mostly via two major routes (i) lymph nodes and (ii) blood...
-
Metastatic lymph node targeted CTLA4 blockade: a potent intervention for local and distant metastases with minimal ICI-induced pneumonia
BackgroundImmune checkpoint blockade (ICB) elicits a strong and durable therapeutic response, but its application is limited by disparate responses...
-
Genetic Alterations and Microbial Dysbiosis Underlie Lymph Node Metastasis in Tongue Cancer
Oral cancer presents a significant clinical challenge due to the presence of hidden lymph node metastases, which greatly influence treatment...
-
Can neoadjuvant chemoradiotherapy before lateral pelvic lymph node dissection improve local control and prognosis in rectal cancer patients with clinically suspected lateral lymph node metastasis? A multicenter lateral node study in China
AimsSelective lateral pelvic lymph node (LPN) dissection (LPND) following neoadjuvant chemoradiotherapy (nCRT) for rectal cancer is widely...
-
Incidence of inguinofemoral lymph node metastases at the first local recurrence of vulvar cancer: a Dutch nationwide study
BackgroundUp to 40% of vulvar cancer patients present with local recurrence within 10 years of follow-up. An inguinofemoral lymphadenectomy (IFL) is...
-
Genetic trajectory and clonal evolution of multiple primary lung cancer with lymph node metastasis
Multiple primary lung cancer (MPLC) with lymph node metastasis (LNM) is a rare phenomenon of multifocal lung cancer. The genomic landscapes of MPLC...
-
Relative impact of lymph-node metastasis and seminal vesical invasion on oncologic outcomes following radical prostatectomy
BackgroundWhile both seminal vesicle (SVI) and lymph-node invasion (LNI) have been identified as adverse prognostic variables among men undergoing...
-
Putative anoikis resistant subpopulations are enriched in lymph node metastases and indicate adverse prognosis in colorectal carcinoma
Anoikis refers to apoptosis induced by the loss of contact with the extracellular matrix. Anoikis resistance is essential for metastasis. We have...
-
Clinical implications of micro lymph node metastasis for patients with gastric cancer
BackgroundLymph node size is considered as a criterion for possible lymph node metastasis in imageology. Micro lymph nodes are easily overlooked by...
-
Selective omission of sentinel lymph node biopsy in mastectomy for ductal carcinoma in situ: identifying eligible candidates
BackgroundSentinel lymph node biopsy (SLNB) is recommended for patients with ductal carcinoma in situ (DCIS) undergoing mastectomy, given the...
-
Development of a nomogram for prediction of central lymph node metastasis of papillary thyroid microcarcinoma
BackgroundPapillary thyroid carcinoma (PTC) is the most frequent malignant tumor in thyroid carcinoma. The aim of this study was to explore the risk...
-
Mesenchymal–epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expression
BackgroundOral squamous cell carcinoma (OSCC), an HPV-negative head and neck cancer, frequently metastasizes to the regional lymph nodes but only...
