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Regional Onco-Sphere: Lymph Node Metastasis
During cancer metastasis, cancer cells spread by dissemination into nearby normal tissue mostly via two major routes (i) lymph nodes and (ii) blood... -
Clinical implications of micro lymph node metastasis for patients with gastric cancer
BackgroundLymph node size is considered as a criterion for possible lymph node metastasis in imageology. Micro lymph nodes are easily overlooked by...
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Genetic Alterations and Microbial Dysbiosis Underlie Lymph Node Metastasis in Tongue Cancer
Oral cancer presents a significant clinical challenge due to the presence of hidden lymph node metastases, which greatly influence treatment... -
Immune characteristics associated with lymph node metastasis in early-stage NSCLC
PurposeTumor metastasis significantly impacts the prognosis of non-small cell lung cancer (NSCLC) patients, with lymph node (LN) metastasis being the...
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Pathologic Assessment of Lymph Node Metastasis
The pathologic assessment and evaluation of lymph node status plays a central role in the diagnosis, staging, and management of most malignancies.... -
Nomogram for predicting lymph node metastasis in patients with ovarian cancer using ultrasonography: a multicenter retrospective study
BackgroundOvarian cancer is a common cancer among women globally, and the assessment of lymph node metastasis plays a crucial role in the treatment...
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Occult lymph node metastasis is not a favorable factor for resected NSCLC patients
BackgroundThis study was to compare the clinical presentations and survivals between the non-small cell lung cancer (NSCLC) patients with occult...
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Can neoadjuvant chemoradiotherapy before lateral pelvic lymph node dissection improve local control and prognosis in rectal cancer patients with clinically suspected lateral lymph node metastasis? A multicenter lateral node study in China
AimsSelective lateral pelvic lymph node (LPN) dissection (LPND) following neoadjuvant chemoradiotherapy (nCRT) for rectal cancer is widely...
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Development of a nomogram for prediction of central lymph node metastasis of papillary thyroid microcarcinoma
BackgroundPapillary thyroid carcinoma (PTC) is the most frequent malignant tumor in thyroid carcinoma. The aim of this study was to explore the risk...
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Relative impact of lymph-node metastasis and seminal vesical invasion on oncologic outcomes following radical prostatectomy
BackgroundWhile both seminal vesicle (SVI) and lymph-node invasion (LNI) have been identified as adverse prognostic variables among men undergoing...
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Reprogramming of sentinel lymph node microenvironment during tumor metastasis
Metastasis is a major cause of death in patients with cancer. The two main routes for cancer cell dissemination are the blood and lymphatic systems....
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Deep learning radiomics based prediction of axillary lymph node metastasis in breast cancer
This study aimed to develop and validate a deep learning radiomics nomogram (DLRN) for the preoperative evaluation of axillary lymph node (ALN)...
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Acetone compression improves lymph node yield and metastasis detection in colorectal cancer
Lymph node status is one of the most important prognostic factors in colorectal cancer, and accurate pathological nodal staging and detection of...
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The role of adenocarcinoma subtypes and immunohistochemistry in predicting lymph node metastasis in early invasive lung adenocarcinoma
BackgroundIdentifying lymph node metastasis areas during surgery for early invasive lung adenocarcinoma remains challenging. The aim of this study...
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Genetic trajectory and clonal evolution of multiple primary lung cancer with lymph node metastasis
Multiple primary lung cancer (MPLC) with lymph node metastasis (LNM) is a rare phenomenon of multifocal lung cancer. The genomic landscapes of MPLC...
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Implications of ZNF334 gene in lymph node metastasis of lung SCC: potential bypassing of cellular senescence
BackgroundThe primary goal of this work is to identify biomarkers associated with lung squamous cell carcinoma and assess their potential for early...
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Nomogram to predict central lymph node metastasis in papillary thyroid carcinoma
Central lymph node metastasis (CLNM) of papillary thyroid carcinoma (PTC) is common. In our study, we built a nomogram to predict CLNM. We...
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Interrogating the roles of lymph node metastasis in systemic immune surveillance
Lymph nodes (LNs) are principal orchestrators of the adaptive immune response, yet in the context of malignancy, they are typically the first sites...
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Colorectal cancer lymph node metastasis prediction with weakly supervised transformer-based multi-instance learning
Lymph node metastasis examined by the resected lymph nodes is considered one of the most important prognostic factors for colorectal cancer (CRC)....
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Prognostic factors and the role of primary debulking in operable stage IVB ovarian cancer with supraclavicular lymph node metastasis: a retrospective study in Chinese patients
BackgroundRecent studies showed heterogeneity in stage IVB patients. However, few studies focused on the prognosis of supraclavicular metastatic...