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Infection prevention and control (IPC) implementation in low-resource settings: a qualitative analysis
BackgroundThe coronavirus disease-2019 (COVID-19) pandemic has again demonstrated the critical role of effective infection prevention and control...
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Community-integrated self-collected HPV-based cervix screening in a low-resource rural setting: a pragmatic, cluster-randomized trial
Effective approaches to improve coverage of self-collected human papillomavirus (HPV)-based cervix screening (SCS) as well as attendance at treatment...
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Strategies for diagnosis and management of CMMRD in low-resource countries: report of a Tunisian family
Constitutional Mismatch Repair Deficiency (CMMRD) is a rare childhood cancer predisposition syndrome, caused by biallelic pathogenic germline...
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Exploring the use of cluster analysis to assess antibiotic stewardship in critically-ill neonates in a low resource setting
BackgroundSepsis is the third leading cause of neonatal death in low and middle-income countries, accounting for one third of all deaths in Ethiopia....
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Estimating cancer incidence in Uganda: a feasibility study for periodic cancer surveillance research in resource limited settings
BackgroundPopulation based cancer registries (PBCRs) are accepted as the gold standard for estimating cancer incidence in any population. However,...
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Diagnosis of Scabies in Resource-Poor Settings
Clinical examination, by mid-level healthcare workers, is the mainstay of scabies diagnosis in resource poor-settings. The implementation of...
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Genetic Epidemiology and Clinical Characteristics of Patients with Spinocerebellar Ataxias in an Unexplored Brazilian State, Using Strategies for Resource-Limited Settings
Spinocerebellar ataxias (SCAs) have a worldwide average prevalence of 2.7 cases per 100,000 individuals, with significant geographic variability....
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MinION Whole-Genome Sequencing in Resource-Limited Settings: Challenges and Opportunities
Purpose of ReviewThe introduction of MinION whole-genome sequencing technology greatly increased and simplified complete genome sequencing in various...
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The application of long-read sequencing in clinical settings
Long-read DNA sequencing technologies have been rapidly evolving in recent years, and their ability to assess large and complex regions of the genome...
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Antimicrobial stewardship in primary health care programs in humanitarian settings: the time to act is now
Fragile and conflict-affected settings bear a disproportionate burden of antimicrobial resistance, due to the compounding effects of weak health...
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Evaluating the implementation of cervical cancer screening programs in low-resource settings globally: a systematized review
PurposeCervical cancer disproportionately burdens low-resource populations where access to quality screening services is limited. A greater...
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Evaluating a novel, low-cost technique for cervical-spine immobilization for application in resource-limited LMICs: a non-inferiority trial
Study designNon-inferiority trial.
ObjectiveLimited cervical spinal (c-spine) immobilization in resource-limited settings of LMICs suggests...
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Physicochemical compatibility of caffeine citrate and caffeine base injections with parenteral medications used in neonatal intensive care settings
PurposeTo investigate the physicochemical compatibility of caffeine citrate and caffeine base injections with 43 secondary intravenous (IV) drugs...
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Feasibility of delivering parent-implemented NDBI interventions in low-resource regions: a pilot randomized controlled study
BackgroundThis implementation feasibility study was conducted to determine whether an evidence-based parent-implemented distance-learning...
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It’s Not Always Easy: Cancer Survivorship Care in Primary Care Settings
By 2040, an anticipated 26.1 million people with a history of cancer will be part of the healthcare system. The purpose of this study was to explore...
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Inherited Pediatric Cancer in Low- and Intermediate-Resource Countries
Childhood cancer statistics are scarce and incomplete in most emerging and low-income countries (ELIC), in which up to 75% of the cases may arise. In...
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Pharmacogenetics in develo** countries and low resource environments
While significant advances have been made in pharmacogenetics (PGx), especially in countries with developed economies, this field remains at its...
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Financial incentives for COVID-19 vaccines in a rural low-resource setting: a cluster-randomized trial
We implemented a clustered randomized controlled trial with 6,963 residents in six rural Ghana districts to estimate the causal impact of financial...
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Protein-Based Biomarkers for the Diagnosis of Malaria in Point-of-Care Settings
Malaria treatment and management may be greatly facilitated by introducing fast, inexpensive, and reliable detection devices. Moreover, the World...