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Re-UNet: a novel multi-scale reverse U-shape network architecture for low-dose CT image reconstruction
AbstractIn recent years, the growing awareness of public health has brought attention to low-dose computed tomography (LDCT) scans. However, the CT...
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Generating synthetic CT from low-dose cone-beam CT by using generative adversarial networks for adaptive radiotherapy
ObjectiveTo develop high-quality synthetic CT (sCT) generation method from low-dose cone-beam CT (CBCT) images by using attention-guided generative...
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Strided Self-Supervised Low-Dose CT Denoising for Lung Nodule Classification
Lung nodule classification based on low-dose computed tomography (LDCT) images has attracted major attention thanks to the reduced radiation dose and...
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Low-dose nivolumab in advanced hepatocellular carcinoma
BackgroundThe approved dose of nivolumab is 3 mg/kg or a flat dose of 240 mg for indications. There is no dose-response relationship for nivolumab;...
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Identification of DNA methylation biomarkers for evaluating cardiovascular disease risk from epigenome profiles altered by low-dose ionizing radiation
BackgroundEnvironmental exposure, medical diagnostic and therapeutic applications, and industrial utilization of radionuclides have prompted a...
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Is low-dose computed tomography for lung cancer screening conveniently accessible in China? A spatial analysis based on cross-sectional survey
BackgroundRegular Low-Dose Computed Tomography (LDCT) for lung cancer high-risk population has been proved to improve health outcomes and relieve...
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Low-dose metronomic cisplatin as an antiangiogenic and anti-inflammatory strategy for cancer
BackgroundConventional chemotherapy is based on the maximum tolerated dose (MTD) and requires treatment-free intervals to restore normal host cells....
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Non-linear dose response of DNA double strand breaks in response to chronic low dose radiation in individuals from high level natural radiation areas of Kerala coast
BackgroundThe human population living in high level natural radiation areas (HLNRAs) of Kerala coast provide unique opportunities to study the...
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Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults
Over one million European children undergo computed tomography (CT) scans annually. Although moderate- to high-dose ionizing radiation exposure is an...
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Ultra-low-dose radiotherapy in the treatment of ocular adnexal lymphoma: a prospective study
PurposeThis single-arm, prospective, exploratory study investigated the effectiveness of ultra-low-dose radiotherapy in the treatment of ocular...
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Prediction of pathologic complete response after single-dose MR-guided partial breast irradiation in low-risk breast cancer patients: the ABLATIVE-2 trial—a study protocol
BackgroundPartial breast irradiation (PBI) is standard of care in low-risk breast cancer patients after breast-conserving surgery (BCS)....
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The Role of Colour Segmented Fluorescence (CSF) Mode and Same-day Administration of Low-dose Indocyanine Green in Liver Surgery: Our Initial Experience
Indocyanine green (ICG) fluorescence image guidance (I-FIGS) is increasingly used in liver surgery. Several regimens have been described regarding...
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Clinical features and risk factors for interstitial lung disease spreading in low-dose irradiated areas after definitive radiotherapy with or without durvalumab consolidation therapy for patients with non-small cell lung cancer
BackgroundThe current standard of care for patients with unresectable locally advanced non-small cell lung cancer (NSCLC) is chemoradiotherapy (CRT)...
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Investigating the Synergistic Potential of Low-Dose HDAC3 Inhibition and Radiotherapy in Alzheimer’s Disease Models
We have previously shown that histone deacetylase (HDAC) inhibition and cranial radiotherapy (RT) independently improve molecular and behavioral...
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Single low-dose INC280-loaded theranostic nanoparticles achieve multirooted delivery for MET-targeted primary and liver metastatic NSCLC
BackgroundNon-small cell lung cancer (NSCLC) patients with primary tumors and liver metastases have substantially reduced survival. Since...
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Monitoring Very Low Dose Radiation Damage in DNA Using “Field-Friendly” Biomarkers
The retrospective assessment of radiation exposures using quantitative biomarkers related to dose is well established for the purpose of biological...
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Development and validation of survival prognostic models for head and neck cancer patients using machine learning and dosiomics and CT radiomics features: a multicentric study
BackgroundThis study aimed to investigate the value of clinical, radiomic features extracted from gross tumor volumes (GTVs) delineated on CT images,...
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Impact of metronomic trabectedin combined with low-dose cyclophosphamide on sarcoma microenvironment and correlation with clinical outcome: results from the TARMIC study
Soft tissue sarcomas (STS) are diverse mesenchymal tumors with few therapeutic options in advanced stages. Trabectedin has global approval for...
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Three-dimensional CT imaging in extensor tendons using deep learning reconstruction: optimal reconstruction parameters and the influence of dose
The purpose of this study was to assess the optimal reconstruction parameters and the influence of tube current in extensor tendons three-dimensional...
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A cost-effectiveness analysis of lung cancer screening with low-dose computed tomography and a polygenic risk score
IntroductionSeveral studies have proved that Polygenic Risk Score (PRS) is a potential candidate for realizing precision screening. The effectiveness...
