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Biosafety assessments of hexafluoropropylene trimer derivative as a fluorinated cooling fluid for electronics
The Internet Data Center (IDC) is one of the most important infrastructures in the field of information technology. The cooling system for heat...
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Local cooling during hot water immersion improves perceptions without inhibiting the acute interleukin-6 response
PurposePassive elevation of body temperature can induce an acute inflammatory response that has been proposed to be beneficial; however, it can be...
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Evoking natural thermal perceptions using a thin-film thermoelectric device with high cooling power density and speed
Multimodal sensory feedback from upper-limb prostheses can increase their function and usability. Here we show that intuitive thermal perceptions...
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Pre-cooling with ingesting a high-carbohydrate ice slurry on thermoregulatory responses and subcutaneous interstitial fluid glucose during heat exposure
The purpose of this study was to compare the effects of ingesting ice slurries with two different carbohydrate contents on body temperatures and the...
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A Thermoelectric System for the Treatment of Periodontal Diseases by Local Hypothermia
The design of a thermoelectric system (TES) for the treatment of periodontal diseases by the method of local hypothermia is discussed. Results from...
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Local alternating heat and cold stimulation affects hemodynamics and oxygenation in fatigued muscle tissue and autonomic nervous activity: a single-arm interventional study
BackgroundLocal alternating heat and cold stimulation as an alternative to contrast bath may cause intermittent vasoconstriction and vasodilation,...
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Local delivery of doxorubicin prodrug via lipid nanocapsule–based hydrogel for the treatment of glioblastoma
Glioblastoma (GBM) recurrences appear in most cases around the resection cavity borders and arise from residual GBM cells that cannot be removed by...
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Intermittent face cooling reduces perceived exertion during exercise in a hot environment
BackgroundFacial cooling (FC) is effective in improving endurance exercise performance in hot environments. In this study, we evaluated the impact of...
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Suppression of local inflammation via galectin-anchored indoleamine 2,3-dioxygenase
The treatment of chronic inflammation with systemically administered anti-inflammatory treatments is associated with moderate-to-severe side effects,...
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A Mathematical Model of a Thermoelectric Device for the Treatment of Whitlow by Local Hypothermia
A mathematical model of a thermoelectric device for the treatment of whitlow by local hypothermia is discussed. The model is based on a solution of...
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The effects of local cooling rates on perfusion of sacral skin under externally applied pressure in people with spinal cord injury: an exploratory study
Study designExperimental before–after design.
ObjectivesThe objectives of this study were to explore the effects of local cooling rates on perfusion...
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Phenotype Shifting in Astrocytes Account for Benefits of Intra-Arterial Selective Cooling Infusion in Hypertensive Rats of Ischemic Stroke
The translational failure of neuroprotective therapies in stroke may be influenced by the mismatch of existing comorbidities between animal models...
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Climate Change and Health: Local Solutions to Local Challenges
Purpose of ReviewClimate change has direct impacts on human health, but those impacts vary widely by location. Local health impacts depend on a large...
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Two new photoactive metal-organic compounds for degradation of methylene blue and treatment in ophthalmic local anesthesia
Two new metal-organic compounds, namely [Cu(CrO 4 )(4,4’-bipy)(H 2 O)]·n(H 2 O) ( 1 ) together with [Mn(Cr 2 O 7 )(bpp) 2 ] n ( 2 ) (4,4’-bipy is 4,4’-bipyridine and...
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Fibroblast activation protein-targeted near-infrared photoimmunotherapy depletes immunosuppressive cancer-associated fibroblasts and remodels local tumor immunity
BackgroundCancer-associated fibroblasts (CAFs) in the tumor microenvironment (TME) play a critical role in tumor immunosuppression. However, targeted...
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Muscle cooling modulates tissue oxidative and biochemical responses but not energy metabolism during exercise
PurposeThis study investigated whether muscle cooling and its associated effects on skeletal muscle oxidative responses, blood gases, and hormonal...
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Action of GABAB receptor on local network oscillation in somatosensory cortex of oral part: focusing on NMDA receptor
The balance of activity between glutamatergic and GABAergic networks is particularly important for oscillatory neural activities in the brain. Here,...
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Unravelling the importance of the eukaryotic and bacterial communities and their relationship with Legionella spp. ecology in cooling towers: a complex network
BackgroundCooling towers are a major source of large community-associated outbreaks of Legionnaires’ disease, a severe pneumonia. This disease is...
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Local immune cell contributions to fracture healing in aged individuals – A novel role for interleukin 22
With increasing age, the risk of bone fractures increases while regenerative capacity decreases. This variation in healing potential appears to be...
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Electro-Thermal Therapy Algorithms and Active Internal Electrode Cooling Reduce Thermal Injury in High Frequency Pulsed Electric Field Cancer Therapies
Thermal tissue injury is an unintended consequence in current irreversible electroporation treatments due to the induction of Joule heating during...