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Alliance for clinical trials in Oncology (Alliance) trial A022101/NRG-GI009: a pragmatic randomized phase III trial evaluating total ablative therapy for patients with limited metastatic colorectal cancer: evaluating radiation, ablation, and surgery (ERASur)
BackgroundFor patients with liver-confined metastatic colorectal cancer (mCRC), local therapy of isolated metastases has been associated with...
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Prognostic utility of systemic inflammatory markers and chronic hepatitis C virus infection status in hepatocellular carcinoma patients treated with local ablation
BackgroundHepatocellular carcinoma (HCC) has high incidence and mortality worldwide. Local ablation using radiofrequency ablation (RFA) or microwave...
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Combination Therapy of Mesenchymal Stem Cell Transplantation and Astrocyte Ablation Improve Remyelination in a Cuprizone-Induced Demyelination Mouse Model
Astrocytes display an active, dual, and controversial role in multiple sclerosis (MS), a chronic inflammatory demyelination disorder. However,...
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Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study
PurposeTo compare the therapeutic efficacy and safety of microwave ablation (MWA) and lauromacrogol injection for ablation (LIA) for benign...
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US-guided ablation of tumors – where is it used and how did we get there
Ablation under ultrasound (US) guidance for the treatment of various tumors in liver, thyroid, prostate, kidney, uterine and many other organs...
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Injectable hydrogel systems for local cancer therapy
BackgroundInjectable hydrogels have attracted significant attention for localized cancer treatment due to their tuned viscoelasticity, self-healing...
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Targeted exome-based predictors of patterns of progression of colorectal liver metastasis after percutaneous thermal ablation
BackgroundPercutaneous thermal ablation is a curative-intent locoregional therapy (LRT) for selected patients with unresectable colorectal liver...
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Stereotactic body radiotherapy for metastatic sarcoma to the lung: adding to the arsenal of local therapy
IntroductionConventional treatment of pulmonary metastatic sarcoma primarily involves surgery, with systemic therapy added in select patients....
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Non-Fourier Bioheat Transfer Analysis in Brain Tissue During Interstitial Laser Ablation: Analysis of Multiple Influential Factors
This work presents the dual-phase lag-based non-Fourier bioheat transfer model of brain tissue subjected to interstitial laser ablation. The finite...
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Botulinum Toxin Therapy-Future Perspectives
New potential applications for botulinum neurotoxin (BoNT) therapy are constantly emerging through the expanding literature in the field of clinical...
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The role of adjuvant transcatheter arterial chemoembolization following repeated curative resection/ablation for hepatocellular carcinoma with early recurrence: a propensity score matching analysis
BackgroundThe role of adjuvant transcatheter arterial chemoembolization (TACE) following repeated resection/ablation for recurrent hepatocellular...
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Trans - Perineal laser ablation of the prostate in high surgical risk patients affected by severe lower urinary tract symptoms related to benign prostatic obstruction
BackgroundIn our study, we aimed to test the efficacy and safety of Trans-Perineal Laser Ablation of the prostate (TPLA®) in the surgical treatment...
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Clinical added value of MRI to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO): study protocol for an international multicentre prospective diagnostic accuracy study
BackgroundAbdominal computed tomography (CT) is the standard imaging method for patients with suspected colorectal liver metastases (CRLM) in the...
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Safety of pulsed field ablation in more than 17,000 patients with atrial fibrillation in the MANIFEST-17K study
Pulsed field ablation (PFA) is an emerging technology for the treatment of atrial fibrillation (AF), for which pre-clinical and early-stage clinical...
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The Impact of Standard Ablation Strategies for Atrial Fibrillation on Cardiovascular Performance in a Four-Chamber Heart Model
PurposeAtrial fibrillation is one of the most frequent cardiac arrhythmias in the industrialized world and ablation therapy is the method of choice...
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Ablative minimally invasive surgical therapies for benign prostatic hyperplasia: A review of Aquablation, Rezum, and transperineal laser prostate ablation
IntroductionBenign prostatic hyperplasia (BPH) is one of the most common diseases affecting men and can present with bothersome lower urinary tract...
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The Enlargement of Ablation Area by Electrolytic Irreversible Electroporation (E-IRE) Using Pulsed Field with Bias DC Field
Irreversible electroporation (IRE) by high-strength electric pulses is a biomedical technique that has been effectively used for minimally invasive...
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LAG3 blockade coordinates with microwave ablation to promote CD8+ T cell-mediated anti-tumor immunity
BackgroundThe immune checkpoint inhibitors (ICIs) combined with other therapeutic strategies have shown exciting results in various malignancies, and...
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Dynamic changes of phenotype and function of natural killer cells in peripheral blood before and after thermal ablation of hepatitis B associated hepatocellular carcinoma and their correlation with tumor recurrence
BackgroundThermal therapy induces an immune response in patients with hepatocellular carcinoma (HCC), but the dynamic characteristics of the natural...
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MR-guided microwave ablation of hepatocellular carcinoma (HCC): is general anesthesia more effective than local anesthesia?
BackgroundPercutaneous magnetic resonance-guided (MR-guided) MWA procedures have traditionally been performed under local anesthesia (LA) and...
