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  1. Fine map** of the Cepaea nemoralis shell colour and mid-banded loci using a high-density linkage map

    Molluscs are a highly speciose phylum that exhibits an astonishing array of colours and patterns, yet relatively little progress has been made in...

    Margrethe Johansen, Suzanne Saenko, ... Angus Davison in Heredity
    Article Open access 27 September 2023
  2. The first linkage map for Australo-Papuan Treefrogs (family: Pelodryadidae) reveals the sex-determination system of the Green-eyed Treefrog (Litoria serrata)

    Amphibians represent a useful taxon to study the evolution of sex determination because of their highly variable sex-determination systems. However,...

    Lorenzo V. Bertola, Conrad J. Hoskin, ... Megan Higgie in Heredity
    Article Open access 04 August 2023
  3. A Recombination Suppressed Region of Sunflower (Helianthus annuus L.) Linkage Group 13 Covers Restoration of Fertility (Rf1) and Downy Mildew Resistance (Pl) Gene Clusters

    Abstract

    A number of genes that control traits that are valuable for breeding introgressed from wild relatives, i.e., pollen-fertility restoration and...

    I. N. Anisimova, N. V. Alpatieva, ... E. E. Radchenko in Russian Journal of Genetics
    Article 01 May 2023
  4. Self-reported HPV vaccination and vaccination record linkage in the Australian Oral Diversity Study

    Purpose

    Australia has a school-based human papillomavirus (HPV) vaccination scheme that was implemented for girls in 2007 and for boys in 2013. HPV...

    Annika Antonsson in Cancer Causes & Control
    Article 31 May 2023
  5. Record linkage based patient intersection cardinality for rare disease studies using Mainzelliste and secure multi-party computation

    Background

    The low number of patients suffering from any given rare diseases poses a difficult problem for medical research: With the exception of...

    Tobias Kussel, Torben Brenner, ... Kay Hamacher in Journal of Translational Medicine
    Article Open access 08 October 2022
  6. Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies

    Linkage disequilibrium (LD) is the correlation among nearby genetic variants. In genetic association studies, LD is often modeled using large...

    Pouria Salehi Nowbandegani, Anthony Wilder Wohns, ... Luke J. O’Connor in Nature Genetics
    Article 28 August 2023
  7. Development of first linkage map for Silphium integrifolium (Asteraceae) enables identification of sporophytic self-incompatibility locus

    Silphium integrifolium ( Asteraceae ) has been identified as a candidate for domestication as a perennial oilseed crop and is assumed to have...

    John H. Price, Andrew R. Raduski, ... Kevin P. Smith in Heredity
    Article 18 April 2022
  8. Combined effects of glycan chain length and linkage type on the immunogenicity of glycoconjugate vaccines

    The development and use of antibacterial glycoconjugate vaccines have significantly reduced the occurrence of potentially fatal childhood and adult...

    Chakkumkal Anish, Michel Beurret, Jan Poolman in npj Vaccines
    Article Open access 10 December 2021
  9. Establishing a framework for privacy-preserving record linkage among electronic health record and administrative claims databases within PCORnet®, the National Patient-Centered Clinical Research Network

    Objective

    The aim of this study was to determine whether a secure, privacy-preserving record linkage (PPRL) methodology can be implemented in a...

    Daniel Kiernan, Thomas Carton, ... Keith Marsolo in BMC Research Notes
    Article Open access 31 October 2022
  10. Evaluation of the frequency of ABO and Rh-Hr blood-group systems in different acquired cataracts type

    Objectives

    This study evaluated the relationship between acquired cataract’s different types and the ABO and Rh blood classes.

    Methods ...
    Reza Jafari, Hanieh Ahmadi, ... Mahdi Abounoori in BMC Research Notes
    Article Open access 30 September 2023
  11. Noninvasive fetal genoty** of single nucleotide variants and linkage analysis for prenatal diagnosis of monogenic disorders

    Background

    High-cost, time-consuming and complex processes of several current approaches limit the use of noninvasive prenatal diagnosis (NIPD) for...

    Wenman Wu, Xuanyou Zhou, ... Chenming Xu in Human Genomics
    Article Open access 27 July 2022
  12. Estimation of cell-free fetal DNA fraction from maternal plasma based on linkage disequilibrium information

    Cell-free fetal DNA fraction (FF) in maternal plasma is a key parameter affecting the performance of noninvasive prenatal testing (NIPT). Accurate...

    Jia Ju, Jia Li, ... **n ** in npj Genomic Medicine
    Article Open access 12 October 2021
  13. Progress towards a glycoconjugate vaccine against Group A Streptococcus

    The Group A Carbohydrate (GAC) is a defining feature of Group A Streptococcus (Strep A) or Streptococcus pyogenes . It is a conserved and simple...

    Keira Burns, Helge C. Dorfmueller, ... Helen A. Shaw in npj Vaccines
    Article Open access 28 March 2023
  14. A Pyrene Coupled Azaine-linkage Chromo-fluorogenic Probe for Specific Detection of Sarin Gas Stimulant, Diethylchlorophosphate

    Owing to the extreme toxicity and easy synthesis protocol of G-series nerve agents, develo** an efficient sensor for selective detection is...

    Arpita Maiti, Sabbir Ahamed, ... Mahendra Nath Roy in Journal of Fluorescence
    Article 25 May 2024
  15. Optimization of the Mainzelliste software for fast privacy-preserving record linkage

    Background

    Data analysis for biomedical research often requires a record linkage step to identify records from multiple data sources referring to the...

    Florens Rohde, Martin Franke, ... Erhard Rahm in Journal of Translational Medicine
    Article Open access 15 January 2021
  16. The Development of a Genetic Linkage Map of Redcurrant (Ribes rubrum L.) by Means of SSR and SNP DNA Markers

    Abstract

    This work was aimed at compiling the world’s first linkage map of redcurrant with the use of microsatellite and SNP DNA markers. As a result...

    A. V. Pikunova, S. V. Goryunova, ... O. D. Golyaeva in Russian Journal of Genetics
    Article 23 November 2020
  17. Adjuvant radiation therapy and health-related quality of life among older women with early-stage endometrial cancer: an analysis using the SEER-MHOS linkage

    Purpose

    Radiation therapy (RT) has been associated with decreased health-related quality of life (HRQOL) in clinical trials of early-stage endometrial...

    Jihye Park, Erin E. Kent, ... Hazel B. Nichols in Cancer Causes & Control
    Article 02 December 2022
  18. The linkage of NF-κB signaling pathway-associated long non-coding RNAs with tumor microenvironment and prognosis in cervical cancer

    Background

    NF-κB signaling pathway participate closely in regulating inflammation and immune response in many cancers. Long non-coding RNAs (lncRNAs)...

    Xue Feng, Ru Shan, **aomeng Hu in BMC Medical Genomics
    Article Open access 17 July 2023
  19. Reversible stabilization of DNA/PEI complexes by reducible click-linkage between DNA and polymer. A new polyplex concept for lowering polymer quantity

    Nonviral transfection of mammalian cells can be performed with electrostatic complexes (polyplexes) between a plasmid DNA (pDNA) encoding a foreign...

    Delphine Maze, Chantal Pichon, Patrick Midoux in Gene Therapy
    Article 09 February 2023
  20. Fentanyl Exposure and Detection Strategies Utilized by Clinical Trial Participants Seeking Linkage to Opioid Use Disorder Treatment at a Syringe Service Program

    Introduction

    The USA continues to face a fentanyl-driven overdose epidemic. Prior research has demonstrated users of illicit opioids are concerned...

    Dennis P. Watson, Bradley Ray, ... Nicole Gastala in Journal of Medical Toxicology
    Article Open access 04 December 2023
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