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Effects of Bullfrog Sialic Acid–Binding Lectin in Cancer Cells
A cancer cell agglutinin isolated from bullfrog (Rana catesbeiana) eggs was named R. catesbeiana sialic acid–binding lectin (cSBL), because its...
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Lectin-mediated, time-efficient, and high-yield sorting of different morphologically intact nephron segments
The kidney is a highly complex organ equipped with a multitude of miniscule filter-tubule units called nephrons. Each nephron can be subdivided into...
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Surface Glycan Profiling of Extracellular Vesicles by Lectin Microarray and Glycoengineering for Control of Cellular Interactions
BackgroundExtracellular vesicles (EVs) are a group of cell-derived membrane vesicles that carry a variety of cargo such as protein, nucleic acids,...
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Inhibition of mannan-binding lectin associated serine protease (MASP)-2 reduces the cognitive deficits in a mouse model of severe traumatic brain injury
The lectin pathway (LP) of complement mediates inflammatory processes linked to tissue damage and loss of function following traumatic brain injury...
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Purification and functional characterization of lectin from Chenopodium album
Chenopodium album L. is a nutritious and edible vegetable with various health benefits. It has been traditionally used for the treatment of several...
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Glycan Profiling of Viral Glycoproteins with the Lectin Microarray
Recently, structural analyses on the glycans attached to viral surface proteins have been intensively conducted since previous studies demonstrated...
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Heating or ginger extract reduces the content of Pinellia ternata lectin in the raphides of Pinellia tuber
Pinellia tuber, the dried tuber of Pinellia ternata , causes a very strong acridity sensation in the oral and laryngopharynx mucosa when taken orally...
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C-type lectin receptor Dectin-1 blockade on tumour-associated macrophages improves anti-PD-1 efficacy in gastric cancer
BackgroundThis study aimed to investigate the expression and clinical significance of Dendritic cell-associated C-type lectin-1 (Dectin-1) in gastric...
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A C-type lectin from Bothrops jararacussu venom reprograms endothelial cell biology
Snake venoms are intricate mixtures of enzymes and bioactive factors that induce a range of detrimental effects in afflicted hosts. Certain Viperids,...
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Association between c-type lectin-like receptor 2 and microsatellite instability in colorectal cancer: a cross-sectional study
BackgroundAs a transmembrane protein, C-type lectin-like receptor 2 (CLEC-2) is mainly expressed on platelets and released into plasma after platelet...
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Microgramma vacciniifolia Frond Lectin: In Vitro Anti-leishmanial Activity and Immunomodulatory Effects Against Internalized Amastigote Forms of Leishmania amazonensis
PurposeThe treatment of leishmaniasis, an anthropozoonosis caused by Leishmania protozoa, is limited by factors, such as adverse effects, toxicity,...
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C-type lectin 4 of Toxocara canis activates NF-ĸB and MAPK pathways by modulating NOD1/2 and RIP2 in murine macrophages in vitro
Toxocara canis is a parasitic zoonose that is distributed worldwide and is one of the two pathogens causing toxocariasis. After infection, it causes...
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Lectin Staining to Detect Human and Avian Influenza Virus Receptors in the Airway of Nonhuman Primates
Hemagglutinin (HA) on the surface of influenza viruses binds to sialic acids, mainly N-acetylneuraminic acid (Neu5Ac) or N-glycolylneuraminic acid....
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Purified Banana lectin (BanLec) isolated from the ripen pulp of Musa Paradisiaca induces apoptosis in cancer cell lines: in vitro study
The aim of the study was to examine the anticancer activities of banana lectin (BanLec) from the ripen pulp of Musa paradisiaca. In this...
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Mannose-Binding Lectin in Human Health and Disease
Mannose-binding lectin (MBL) plays, as a soluble pattern recognition molecule, a central role in the innate immune response. MBL binds to the surface...
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Lectin and Liquid Chromatography-Based Methods for Immunoglobulin (G) Glycosylation Analysis
Immunoglobulin (Ig) glycosylation has been shown to dramatically affect its structure and effector functions. Ig glycosylation changes have been...
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Comprehensive characterization of Allium cepa leaf lectin (ACAL1) for its potential use against sap-sucking plant pests: in silico study
Monocot mannose-binding lectins (MMBLs) play crucial role in plant protection against sap-sucking insects. In current investigation, onion leaf...
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