Search
Search Results
-
Effect of positive airway pressure compliance on laryngopharyngeal reflux in obstructive sleep apnea patients
ObjectivesTo determine the effect of continuous positive airway pressure (CPAP) compliance on symptoms and signs of laryngopharyngeal reflux (LPR) in...
-
Matrix metalloproteinase-7 induces E-cadherin cleavage in acid-exposed primary human pharyngeal epithelial cells via the ROS/ERK/c-Jun pathway
AbstractLaryngopharyngeal reflux disease (LPRD) is caused by pharyngeal mucosal damage due to the reflux of gastric contents, including acid, pepsin,...
-
Intensity modulated proton therapy for early-stage glottic cancer: high-precision approach to laryngeal function preservation with exceptional treatment tolerability
BackgroundDue to the increasing expertise in transoral laser surgery and image-guided radiation therapy, treatment outcomes have recently improved in...
-
Fluid dynamics of the upper airway in pediatric patients with severe laryngomalacia
Laryngomalacia is the top cause of pediatric laryngeal wheeze. We used computational fluid dynamics to study the inspiratory airflow dynamics in...
-
Impaired parasympathetic function in long-COVID postural orthostatic tachycardia syndrome – a case-control study
PurposeEighty percent of patients infected by SARS-CoV-2 report persistence of one symptom beyond the 4-week convalescent period. Those with...
-
Voice perturbations under the stress overload in young individuals: phenoty** and suboptimal health as predictors for cascading pathologies
Verbal communication is one of the most sophisticated human motor skills reflecting both—the mental and physical health of an individual. Voice...
-
Microparticles, Microspheres, and Microemulsions in Respiratory Diseases
The term microparticles refers to particles that boast in the size range of micrometers. These may be described as solid particles or particulate...
-
An immune-related lncRNA pairs signature to identify the prognosis and predict the immune landscape of laryngeal squamous cell carcinoma
BackgroundLaryngeal squamous cell carcinoma (LSCC) is the most common squamous cell carcinoma. Though significant effort has been focused on...
-
Pepsin promotes IL-8 signaling-induced epithelial–mesenchymal transition in laryngeal carcinoma
BackgroundLaryngopharyngeal reflux (LPR), with its increasing morbidity, is attracting considerable attention. In recent years, the causal role...
-
Synergistic association between underweight and type 2 diabetes on the development of laryngeal cancer: a national population-based retrospective cohort study
BackgroundAlthough cigarette smoking is the most significant risk factor for laryngeal cancer, other risk factors might also be associated with the...
-
Identification of key methylation differentially expressed genes in posterior fossa ependymoma based on epigenomic and transcriptome analysis
BackgroundPosterior fossa ependymoma (EPN-PF) can be classified into Group A posterior fossa ependymoma (EPN-PFA) and Group B posterior fossa...
-
Matrix association region/scaffold attachment region: the crucial player in defining the positions of chromosome breaks mediated by bile acid-induced apoptosis in nasopharyngeal epithelial cells
BackgroundIt has been found that chronic rhinosinusitis (CRS) increases the risk of develo** nasopharyngeal carcinoma (NPC). CRS can be caused by...
-
Identification and potential mechanisms of a 4-lncRNA signature that predicts prognosis in patients with laryngeal cancer
PurposeThis study aimed to describe the use of a novel 4-lncRNA signature to predict prognosis in patients with laryngeal cancer and to explore its...
-
Advanced computing solutions for analysis of laryngeal disorders
Clinical diagnosis of voice pathologies is performed by analyzing audio, color, shape, and vibration patterns of the laryngeal recordings which are...
-
Bile acids at neutral and acidic pH induce apoptosis and gene cleavages in nasopharyngeal epithelial cells: implications in chromosome rearrangement
BackgroundChronic rhinosinusitis (CRS) increases the risk of develo** nasopharyngeal carcinoma (NPC) while nasopharyngeal reflux is known to be one...
-
Hue and Cry
This section covers interesting aspects of tear-based syndromes, artificial tears, those obtained from women in different stages of their lifecycle,...
-
Carcinogenesis of Laryngeal Tumors
Laryngeal cancer is a rare disease comprising 1–2% of all malignancies with an incidence of 1.1% (men 2.1%, women 0.3%) and mortality of 1.0%...
-
Rikkunshito and Ghrelin
Rikkunshito is a kampo herbal medicine which is widely used in Japan for the treatment of the upper gastrointestinal symptoms of patients with...
-
Head-and-neck squamous cell carcinoma risk in smokers: no association detected between phenotype and AHR, CYP1A1, CYP1A2, or CYP1B1 genotype
BackgroundHead-and-neck squamous cell carcinoma (HNSCC) differs between smokers and nonsmokers in etiology and clinical presentation. Because of...
-
Evaluation of Laryngopharyngeal Reflux in Pediatric Patients with Asthma Using a New Technique of Pharyngeal pH-Monitoring
There is a debate about the association between asthma and gastroesophageal and/or laryngopharyngeal reflux (LPR). Pharyngeal pH-monitoring is a new...