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Development and Evaluation of Brief Web-Based Education for Primary Care Providers to Address Inequities in Lung Cancer Screening and Smoking Cessation Treatment
Annual lung cancer screening (LCS) is recommended for individuals at high risk for lung cancer. However, primary care provider–initiated discussions...
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Retrograde amnesia abolishes the self-reference effect in anterograde memory
Is retrograde amnesia associated with an ability to know who we are and imagine what we will be like in the future? To answer this question, we had...
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A comparability study of natural and deglycosylated PD-L1 levels in lung cancer: evidence from immunohistochemical analysis
Emerging evidence has revealed that the removal of N-linked glycosylation could enhance PD-L1 detection. However, whether PD-L1 antibodies against...
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Preclinical and clinical aspects of P2X receptors as a common route in different diseases: A meeting report
PRESTO was established in 2022 and is a concerted effort by leading European experts in the field of P2XRs and extracellular ATP to promote and...
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Sarcoptic Mange in Wild and Domestic Animals
Sarcoptic mange is recognized as a common skin disease caused by Sarcoptes scabiei in a wide range of mammalian species. To date, the infection has...
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Matrix metalloproteinases, purinergic signaling, and epigenetics: hubs in the spinal neuroglial network following peripheral nerve injury
Activation of glial cells (reactive gliosis) and the purinergic pathway, together with metalloproteinase (MMP)-induced remodeling of the neural...
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Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice
RationaleThe use of synthetic cannabinoid receptor agonists (SCRAs) is growing among adolescents, posing major medical and psychiatric risks. JWH-018...
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Blood flow restriction increases necessary muscle excitation of the elbow flexors during a single high-load contraction
PurposeTo investigate the effects of blood flow restriction (BFR) on electromyographic amplitude (EMG RMS )–force relationships of the biceps brachii...
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Multimodal tract-based MRI metrics outperform whole brain markers in determining cognitive impact of small vessel disease-related brain injury
In cerebral small vessel disease (cSVD), whole brain MRI markers of cSVD-related brain injury explain limited variance to support individualized...
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Membrane Progesterone Receptor α (mPRα/PAQR7) Promotes Survival and Neurite Outgrowth of Human Neuronal Cells by a Direct Action and Through Schwann Cell-like Stem Cells
We recently showed that membrane progesterone receptor α (mPRα/PAQR7) promotes pro-regenerative effects in Schwann cell-like adipose stem cells...
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A comparison of techniques for verifying the accuracy of precision decomposition-derived relationships between motor unit firing rates and recruitment thresholds from surface EMG signals
Approaches for validating motor unit firing times following surface electromyographic (EMG) signal decomposition with the precision decomposition III...
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Fine-Tuning the Immune Response Against Cancer with Antibody-Cytokine Fusion Proteins
Antibody-cytokine fusion proteins, also known as immunocytokines, comprise a novel class of biopharmaceuticals designed to localize immunomodulatory...
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Alkoxy chain length governs the potency of 2-benzylbenzimidazole ‘nitazene’ opioids associated with human overdose
RationaleNovel synthetic opioids (NSOs) are emerging in recreational drug markets worldwide. In particular, 2-benzylbenzimidazole ‘nitazene’...
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Efficacy and safety of granulocyte–macrophage colony-stimulating factor (GM-CSF) antibodies in COVID-19 patients: a meta-analysis
ObjectiveThis study aims to determine the efficacy and safety of granulocyte–macrophage colony-stimulating factor (GM-CSF) antibodies in COVID-19...
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The Coordinating Role of the Actin Cytoskeleton in Short-Term Neural Network Plasticity Involving Excitatory and Inhibitory Synapses
The problem of frequency coding is closely related to studies of the mechanisms by which inhibitory interneurons are involved in neural network...
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Pulmonary inflammation, oxidative stress, and fibrosis in a mouse model of cholestasis: the potential protective properties of the dipeptide carnosine
Cholestasis is a clinical complication that primarily influences the liver. However, it is well known that many other organs could be affected by...
