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Electrochemical Sensors and Biosensors for the Detection of Cancer Biomarkers and Drugs
Cancer has been posing a global health concern due to an increasing number of people who have been struggling day by day. The fight against this... -
Forty years of the adrenal chromaffin cell through ISCCB meetings around the world
This historical review focuses on the evolution of the knowledge accumulated during the last two centuries on the biology of the adrenal medulla...
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Biomarkers and neuromodulation techniques in substance use disorders
Addictive disorders are a severe health concern. Conventional therapies have just moderate success and the probability of relapse after treatment...
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Biosensors Based on Nanomaterials: Transducers and Modified Surfaces for Diagnostics
The use of nanoparticles has opened a new era in the development of nanobiosensors capable of achieving analytical responses that compete with the... -
Potential Diagnostic Systems for Coronavirus Detection: a Critical Review
AbstractCurrently there are no effective anti-viral drugs for SARS-CoV-2, so the primary line of defense is to detect infected cases as soon as...
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A simplified and miniaturized glucometer-based assay for the detection of β-glucosidase activity
β-Glucosidase activity assays constitute an important indicator for the early diagnosis of neonatal necrotizing enterocolitis and qualitative changes...
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Active High-Density Electrode Arrays: Technology and Applications in Neuronal Cell Cultures
Active high-density electrode arrays realized with complementary metal–oxide–semiconductor (CMOS) technology provide electrophysiological recordings... -
GABAB Receptor Functions in the Mesolimbic Dopamine System
GABAB receptors are expressed in neurons of the dopamine system where they bidirectionally modulate activity and release of glutamate, GABA, and... -
Electrochemical Biosensors for miRNA Detection
MicroRNAs (miRNAs) are intensely studied as candidates for diagnostic and prognostic biomarkers. They are naturally occurring small RNAs... -
Electrophysiologic Measurements of Membrane Capacitance in Hormone-Secreting Cells
Many methods have been developed for the study of exo- and endocytosis. One of the most elegant consists of cellular membrane capacitance... -
Determination of Cyanogenic Compounds in Edible Plants by Ion Chromatography
Cyanogenic glycosides are HCN-producing phytotoxins; HCN is a powerful and a rapidly acting poison. It is not difficult to find plants containing...
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Effect of physiological harvest stages on the composition of bioactive compounds in Cavendish bananas
The combined influence of maturation, ripening, and climate on the profile of bioactive compounds was studied in banana ( Musa acuminata , AAA,...
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Microdialysis and Advances for Sampling Synaptic and Extrasynaptic Pools
Intercellular communication plays a key role in information processing in the nervous system, to immune response, to cellular growth and... -
Electrocatalytic response of poly(cobalt tetraaminophthalocyanine)/multi-walled carbon nanotubes-Nafion modified electrode toward sulfadiazine in urine
A highly sensitive amperometric sulfadiazine sensor fabricated by electrochemical deposition of poly(cobalt tetraaminophthalocyanine) (poly(Co II TAPc))...
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Development of an electrochemical immunoassay for detection of gatifloxacin in swine urine
To detect gatifloxacin (GAT) residue in swine urine, an electrochemical immunoassay was established. An indirect competitive immunoassay was...
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PKC epsilon facilitates recovery of exocytosis after an exhausting stimulation
It has been well documented that protein kinase Cs (PKCs) play multifaceted roles in regulating exocytosis of neurotransmitters and hormones. But the...
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Phenolic compounds in olive oil: antioxidant, health and organoleptic activities according to their chemical structure
Hydrophilic phenols are the most abundant natural antioxidants of virgin olive oil (VOO), in which, however, tocopherols and carotenes are also...
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Dysbindin-1 and Its Protein Family
Variation in the gene encoding dysbindin-1 (i.e., dystrobrevin-binding protein 1: DTNBP1) has frequently been associated with schizophrenia. Several... -
Short-term exposure to somatostatin or muscarinic agonists reduce acetylcholine-induced 3H-MPP+ release from bovine adrenal medullary cells
The aim of this work was to investigate the effect of a short-term exposure to somatostatin (SS), its receptors (SSTR) selective agonists as well as...
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A comparison between exocytic control mechanisms in adrenal chromaffin cells and a glutamatergic synapse
It has been known since the work of Katz and collaborators in the early 1950s that an increase in intracellular Ca ++ concentration ([Ca ++ ]) is the...