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1. Conventional Method of Cardiac Ischemia/Reperfusion Injury in Mice

   Myocardial ischemia-reperfusion injury (IRI) after myocardial ischemia, cardiac surgery, or circulatory arrest leads to adverse cardiovascular...

   Sunghye Cho, Dongtak Jeong in Experimental Models of Cardiovascular Diseases

   Protocol 2024
   

2. The Protective Role of Transcript-Induced in Spermiogenesis 40 in Cerebral Ischemia–Reperfusion Injury

   Prompt reperfusion after cerebral ischemia is important to maintain neuronal survival and reduce permanent disability and death. However, the...

   **g **e, Lei Wang, ... Lang wang in Neurochemical Research

   Article 17 June 2024
   

3. Anti-aging Factor GRSF1 Attenuates Cerebral Ischemia-Reperfusion Injury in Mice by Inhibiting GPX4-Mediated Ferroptosis

   Abnormal accumulation of senescent cells in tissues has been shown to facilitate the onset and progression of various diseases. As an important...

   Yanan Li, Qianni Shen, ... Wenwei Gao in Molecular Neurobiology

   Article 20 October 2023
   

4. Targeting PI3K/Akt in Cerebral Ischemia Reperfusion Injury Alleviation: From Signaling Networks to Targeted Therapy

   Ischemia/reperfusion (I/R) injury is a pathological event that results in reperfusion due to low blood flow to an organ. Cerebral ischemia is a...

   Ting Zheng, Taotao Jiang, ... Manxia Wang in Molecular Neurobiology

   Article 05 March 2024
   

5. Mild therapeutic hypothermia upregulates the O-GlcNAcylation level of COX10 to alleviate mitochondrial damage induced by myocardial ischemia–reperfusion injury

   Objective

   Mild therapeutic hypothermia (MTH) is an important method for perioperative prevention and treatment of myocardial ischemia–reperfusion...

   Wei Deng, Yixuan Chen, ... Peng Yu in Journal of Translational Medicine

   Article Open access 22 May 2024
   

6. Regulatory effects of trimetazidine in cardiac ischemia/reperfusion injury

   Ischemia/reperfusion (I/R) injury is a tissue damage during reperfusion after an ischemic condition. I/R injury is induced by pathological cases...

   Mohammad Hosein Farzaei, Fatemeh Ramezani-Aliakbari, ... Iraj Salehi in Naunyn-Schmiedeberg's Archives of Pharmacology

   Article 27 March 2023
   

7. Inflammatory setting, therapeutic strategies targeting some pro-inflammatory cytokines and pathways in mitigating ischemia/reperfusion-induced hepatic injury: a comprehensive review

   Ischemia/reperfusion injury (IRI) is a key determining agent in the pathophysiology of clinical organ dysfunction. It is characterized by an aseptic...

   Moustafa O. Aboelez, Hend A. A. Ezelarab, ... Deiaa E. Elsayed Abouzed in Naunyn-Schmiedeberg's Archives of Pharmacology

   Article 21 April 2024
   

8. Broadening horizons: The role of ferroptosis in myocardial ischemia–reperfusion injury

   Ferroptosis is a novel type of regulated cell death (RCD) discovered in recent years, where abnormal intracellular iron accumulation leads to the...

   Ke Zhao, **aoshu Chen, ... Juan Zhang in Naunyn-Schmiedeberg's Archives of Pharmacology

   Article 29 April 2023
   

9. Deficiency of mindin reduces renal injury after ischemia reperfusion

   Background

   Acute renal injury (AKI) secondary to ischemia reperfusion (IR) injury continues to be a significant perioperative problem and there is no...

   Tao Bai, **ong Wang, ... Pengcheng Luo in Molecular Medicine

   Article Open access 12 December 2022
   

10. TRIM37 exacerbates hepatic ischemia/reperfusion injury by facilitating IKKγ translocation

    Background

    Hepatic ischemia/reperfusion (I/R) injury is one of the major pathological processes associated with various liver surgeries. However,...

    Hang Yang, Zuotian Huang, ... Zhongjun Wu in Molecular Medicine

    Article Open access 08 May 2023
    

11. Pharmacokinetics of 4-Hydroxybenzaldehyde in Normal and Cerebral Ischemia–Reperfusion Injury Rats Based on Microdialysis Technique

    Aim

    4-Hydroxybenzaldehyde (4-HBd) is used for the treatment of headaches, dizziness, and convulsions. The objective of this study was to...

    Chun** Xu, ** Feng, ... Qing Lin in European Journal of Drug Metabolism and Pharmacokinetics

    Article 24 November 2023
    

12. Immune response associated with ischemia and reperfusion injury during organ transplantation

    Background

    Ischemia and reperfusion injury (IRI) is an ineluctable immune-related pathophysiological process during organ transplantation, which not...

    Qiao Tang, Chong Dong, Qian Sun in Inflammation Research

    Article Open access 25 October 2022
    

13. A novel beneficial role of humanin on intestinal apoptosis and dysmotility in a rat model of ischemia reperfusion injury

    A prevalent clinical problem including sepsis, shock, necrotizing enterocolitis, and mesenteric thrombosis is intestinal ischemia/reperfusion (I/R)...

    Eman R. Abozaid, Reham H. Abdel-Kareem, Marwa A. Habib in Pflügers Archiv - European Journal of Physiology

    Article Open access 05 April 2023
    

14. Cerebral Ischemia/Reperfusion Injury and Pharmacologic Preconditioning as a Means to Reduce Stroke-induced Inflammation and Damage

    Stroke is one of the leading causes of death and long-term serious disability. Current therapeutic strategy is limited to thrombolytic agents,...

    Huajun Yang, Chengxuan Qi, ... Qun Wang in Neurochemical Research

    Article 03 November 2022

15. Insulin-induced gene 2 protects against hepatic ischemia–reperfusion injury via metabolic remodeling

    Background

    Hepatic ischemia–reperfusion (IR) injury is the primary reason for complications following hepatectomy and liver transplantation (LT)....

    Yichao Wu, Changbiao Li, ... **ao Xu in Journal of Translational Medicine

    Article Open access 19 October 2023
    

16. Human Serum Albumin-enriched Clopidogrel Bisulfate Nanoparticle Alleviates Cerebral Ischemia–Reperfusion Injury in Rats

    Purpose

    Cerebral ischemia – reperfusion (I/R) injury remains a leading cause of mobility and mortality among patients with ischemic stroke. This study...

    Yiting Luo, Yunli **a, ... Li Deng in Pharmaceutical Research

    Article 08 June 2023
    

17. Impact of folic acid supplementation on ischemia‒reperfusion-induced kidney injury in rats: folic acid prophylactic role revisited

    Folic acid (FA), with its anti-inflammatory and antioxidant properties, may offer protection against ischemia–reperfusion (IR) injury. This study...

    Aya E. H. Hamed, Sherif Khedr, ... Mona A. Ahmed in The Journal of Physiological Sciences

    Article Open access 07 February 2024
    

18. Nanoselenium attenuates renal ischemia-reperfusion injury in rats

    Using selenium (Se) nanoparticles has received attention in recent years because of their therapeutic benefits due to their anticancer, antioxidant,...

    Farzaneh Sadeghmanesh, Akram Eidi, ... Shahrbanoo Oryan in Naunyn-Schmiedeberg's Archives of Pharmacology

    Article 11 October 2023
    

19. Urine Proteomic Signatures of Mild Hypothermia Treatment in Cerebral Ischemia–Reperfusion Injury in Rats

    Mild hypothermia (MH) is an effective measure to alleviate cerebral ischemia–reperfusion (I/R) injury. However, the underlying biological mechanisms...

    Dandan Zhang, Dapeng Li, ... Weiwei Qin in Cellular and Molecular Neurobiology

    Article Open access 05 June 2024
    

20. Mild hypothermia ameliorates hepatic ischemia reperfusion injury by inducing RBM3 expression

    Liver ischemia reperfusion injury (IRI) is a serious complication of certain liver surgeries, and it is difficult to prevent. As a potential...

    Qi **ao, Yuan Liu, ... BiQi Fu in Apoptosis

    Article 05 August 2022