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Postoperative cosmetic outcome of intraoperative radiotherapy in comparison to whole breast radiotherapy in early stage breast cancer; a retrospective cohort study
BackgroundIn this study, we aim to evaluate the cosmetic outcome differences between Intraoperative electron beam radiation therapy (IOERT) and whole...
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Dosimetric evaluation of an intraoperative radiotherapy system: a measurement-based and Monte-Carlo modelling investigation
Intraoperative radiotherapy (IORT) is a specialised subset of radiotherapy, where a high radiation dose is delivered to a surgically exposed tumour...
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Intraoperative electron radiotherapy in early invasive ductal breast cancer: 6-year median follow-up results of a prospective monocentric registry
BackgroundIntraoperative electron radiotherapy (IOERT) can be used to treat early breast cancer during the conservative surgery thus enabling shorter...
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Outcomes of surgical resection and intraoperative electron radiotherapy for patients with para-aortic recurrences of gastrointestinal and gynecologic malignancies
BackgroundPara-aortic lymph node (PALN) metastases from primary pelvic malignancies are often treated with resection, but recurrence is common. We...
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PErspective and current status of Radiotherapy Service in IRan (PERSIR)-1 study: assessment of current external beam radiotherapy facilities, staff and techniques compared to the international guidelines
Background and purposeRadiotherapy (RT) is an essential treatment modality against cancer and becoming even more in demand due to the anticipated...
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Sole adjuvant intraoperative breast radiotherapy in Taiwan: a single-center experience
IntroductionIntraoperative radiotherapy (IORT) is more convenient than standard whole breast external beam radiotherapy (EBRT) as a sole adjuvant...
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Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment
In the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy was non-inferior to whole-breast...
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Electron beam intraoperative radiotherapy for metastatic epidural spinal cord compression: a prospective observational study
To assess the additional effects of intraoperative radiotherapy (IORT) with decompression surgery and adjuvant external beam radiotherapy (EBRT) for...
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Addressing radiotherapy-induced fibrosis: the potential of platelet-rich plasma and infliximab for improved breast cancer management
Breast cancer treatment encompasses various therapeutic modalities, including surgery, radiotherapy, and chemotherapy. Breast-conserving surgery has...
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Safety and feasibility of ultra-long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis : a comparative analysis
BackgroundOur study compares the outcomes of extensive spinal metastasis patients treated with Ultra-Long Construct Navigated Minimally Invasive...
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New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer
BackgroundThe TARGIT-A trial reported risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy for breast cancer to be as...
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Diagnostic accuracy of intraoperative frozen section for margin evaluation of oral cavity squamous cell carcinoma
ObjectivesIntraoperative frozen-section evaluation is a valuable technique for detecting positive margins intraoperatively for oral squamous cell...
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The role of surgical tissue injury and intraoperative sympathetic activation in postoperative immunosuppression after breast-conserving surgery versus mastectomy: a prospective observational study
BackgroundBreast cancer is the second most common cause of death from cancer in women worldwide. Counterintuitively, large population-based...
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Safety of Three-Dimensional Conformal Radiotherapy on the Sheep with Pulmonary Cystic Echinococcosis: A Preliminary Study
PurposeRadiotherapy showed the potential to effectively kill the cysts of pulmonary cystic echinococcosis (CE). However, little is known about its...
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Efficacy analysis of intraoperative radiotherapy in patients with early-stage breast cancer
BackgroundTo analyze the clinical efficacy of intraoperative radiotherapy (IORT) after breast-conserving surgery (BCS) in patients with early-stage...
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125I seed brachytherapy for non-central pelvic recurrence of cervical cancer after external beam radiotherapy
ObjectiveTo investigate the efficacy of 125 I seed brachytherapy for non-central pelvic recurrence of cervical cancer after external beam...
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Long-term outcome after combined kyphoplasty and intraoperative radiotherapy (Kypho-IORT) for vertebral tumors
IntroductionThe spine represents the site which is most frequently affected by bone metastases in patients with systemic cancer. Of all local...
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Fatigue following radiotherapy of low-risk early breast cancer – a randomized controlled trial of intraoperative electron radiotherapy versus standard hypofractionated whole-breast radiotherapy: the COSMOPOLITAN trial (NCT03838419)
BackgroundFatigue is one of the most common and distressing side-effects of breast cancer radiotherapy. According to current guidelines, accelerated...
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A case report on a novel use of intraoperative Intrabeam™ radiation therapy for a recurrent malignant peripheral nerve sheath tumor with sciatic nerve involvement
BackgroundMalignant peripheral nerve sheath tumors (MPNST) are sarcomas that arise from peripheral nerves. They generally have a poor prognosis which...
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Neoadjuvant radiotherapy for resectable retroperitoneal sarcoma: a meta-analysis
BackgroundNeoadjuvant radiotherapy (NRT) for resectable retroperitoneal sarcoma (RPS) has been shown to be systematically feasible. Whether NRT has...
