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The association between serum ferritin levels and malignant intraductal papillary mucinous neoplasms
BackgroundSerum ferritin levels are elevated in many malignancies. In this study, we showed the performance of serum ferritin in identifying...
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Optimal surveillance of intraductal papillary mucinous neoplasms of the pancreas focusing on remnant pancreas recurrence after surgical resection
BackgroundThe international consensus guidelines for intraductal papillary mucinous neoplasm of the pancreas (IPMN) presented clinical features as...
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The application of single-cell sequencing in pancreatic neoplasm: analysis, diagnosis and treatment
Pancreatic neoplasms, including pancreatic ductal adenocarcinoma (PDAC), intraductal papillary mucinous neoplasm (IPMN) and pancreatic cystic...
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Hepatocellular carcinoma and solid pseudopapillary neoplasm of the pancreas complicating familial adenomatous polyposis: two cases and review of the literature
Familial adenomatous polyposis (FAP) is characterized by colorectal polyposis and extracolonic tumors. Adenocarcinoma of the pancreas and...
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Classification prediction of pancreatic cystic neoplasms based on radiomics deep learning models
BackgroundPreoperative prediction of pancreatic cystic neoplasm (PCN) differentiation has significant value for the implementation of personalized...
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Develop Nomogram to Predict Malignancy of Intraductal Papillary Mucinous Neoplasm
A nomogram is a useful graphical tool for presenting a risk prediction and prognosis prediction in medical research. Intraductal papillary mucinous...
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Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis
BackgroundIntraductal papillary neoplasms (IPN) and biliary epithelial neoplasia (BilIN) are well‐defined precursor lesions of biliary tract...
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Precursor lesions in familial and hereditary pancreatic cancer
Infiltrating ductal adenocarcinoma of the pancreas, referred to here as “pancreatic cancer,” is one of the deadliest of all of the solid...
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Talniflumate abrogates mucin immune suppressive barrier improving efficacy of gemcitabine and nab-paclitaxel treatment in pancreatic cancer
BackgroundPancreatic ductal adenocarcinoma (PDAC) is a lethal disease. This is due to its aggressive course, late diagnosis and its intrinsic drugs...
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Histopathological Characteristics: Breast Cancer Subtypes Depending on Receptor Status, Clinical and Pathological Staging of Breast Cancer
Breast cancer (BC) is a clinically heterogeneous disease affecting around 14% female population worldwide with unique histopathological and...
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Role of Hippo pathway dysregulation from gastrointestinal premalignant lesions to cancer
BackgroundFirst identified in Drosophila melanogaster , the Hippo pathway is considered a major regulatory cascade controlling tissue homeostasis and...
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The role of endoscopic ultrasound in the detection of pancreatic lesions in high-risk individuals
Individuals at high risk of develo** pancreatic ductal adenocarcinoma are eligible for surveillance within research programs. These programs employ...
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Surgical aspects related to hereditary pancreatic cancer
The goal of surveillance programs for individuals at risk (IAR) from familial pancreatic cancer (FPC) families or families with other inherited tumor...
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Experimental Model for Pancreatic Cancer and Its Therapeutic Implications in Clinical Research
This book chapter aims to provide an overview knowledge on different animal models that has wide range of research implications in pancreatic cancer...
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Familial pancreatic cancer: a long fruitful journey
In the early years of my GI fellowship, a healthy 40-year-old man came to my clinic and announced that he was going to die of pancreatic cancer. His...
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Splicing alterations in pancreatic ductal adenocarcinoma: a new molecular landscape with translational potential
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers worldwide, mainly due to its late diagnosis and lack of effective...
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Aspects and outcomes of surveillance for individuals at high-risk of pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related deaths and is associated with a poor prognosis. The majority of these...
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Histopathological and Molecular Markers in the Assessment of Prostate Cancer Aggressivity
Prostate cancer (PCa) in most patients does not cause significant clinical symptoms, but high-risk disease, accounting for approximately 15% of PCa,...
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Characteristics of familial pancreatic cancer families with additional colorectal carcinoma
Familial pancreatic cancer (FPC) is a rare hereditary tumor entity with broad phenotypic heterogeneity, including colorectal carcinoma (CRC) in some...
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Preoperative profiles of plasma amino acids and derivatives distinguish periampullary cancer and benign disease
Periampullary cancers, including pancreatic ductal adenocarcinoma, ampullary-, cholangio-, and duodenal carcinoma, are frequently diagnosed in an...
