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Vestibular input modulates step** balance reactions early in the pre-step phase through to post-recovery
Compensatory step** reactions to recover balance are frequently performed, however, the role of sensory feedback in regulating these responses is...
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Lattice 123 pattern for automated Alzheimer’s detection using EEG signal
This paper presents an innovative feature engineering framework based on lattice structures for the automated identification of Alzheimer's disease...
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Central Pattern Generators
Central pattern generators (CPGs) are circuits of neurons – coupled by chemical synapses and often gap junctions (Marder et al., Dev Neurobiol...
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Effect of adult-born immature granule cells on pattern separation in the hippocampal dentate gyrus
Young immature granule cells (imGCs) appear via adult neurogenesis in the hippocampal dentate gyrus (DG). In comparison to mature GCs (mGCs) (born...
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Subthalamic nucleus input-output dynamics are correlated with Parkinson’s burden and treatment efficacy
The subthalamic nucleus (STN) is pivotal in basal ganglia function in health and disease. Micro-electrode recordings of >25,000 recording sites from...
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Pattern classification of interstitial lung diseases from computed tomography images using a ResNet-based network with a split-transform-merge strategy and split attention
In patients with interstitial lung disease (ILD), accurate pattern assessment from their computed tomography (CT) images could help track lung...
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Local synaptic inhibition mediates cerebellar granule cell pattern separation and enables learned sensorimotor associations
The cerebellar cortex has a key role in generating predictive sensorimotor associations. To do so, the granule cell layer is thought to establish...
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Differential frequency-dependent reflex summation of the aortic baroreceptor afferent input
Reflex summation in the expression of left and right aortic baroreflex control of hemodynamic functions was investigated. In anesthetized...
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Discrimination of the moving direction is improved depending on the pattern of the mechanical tactile stimulation intervention
BackgroundThe mechanical tactile stimulation, such as plastic pins and airflow-driven membrane, induces cortical activity. The cortical activity...
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Input-output specific orchestration of aversive valence in lateral habenula during stress dynamics
Stress has been considered as a major risk factor for depressive disorders, triggering depression onset via inducing persistent dysfunctions in...
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Brainstem sources of input to the central mesencephalic reticular formation in the macaque
Physiological studies indicate that the central mesencephalic reticular formation (cMRF) plays a role in gaze changes, including control of...
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Posterior scleral birefringence measured by triple-input polarization-sensitive imaging as a biomarker of myopia progression
In myopic eyes, pathological remodelling of collagen in the posterior sclera has mostly been observed ex vivo. Here we report the development of...
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Cerebellar plasticity based equalization of total input to inferior olive cells
We present a novel biologically plausible model of cerebellar learning. The study includes three substantial points. First, we show that the...
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A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex
Identification of structural connections between neurons is a prerequisite to understanding brain function. Here we developed a pipeline to...
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Effect of adult hippocampal neurogenesis on pattern separation and its applications
Adult hippocampal neurogenesis (AHN) is considered essential in memory formation. The dentate gyrus neural network containing newborn dentate gyrus...
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Modification of temporal pattern sensitivity for inputs from medial entorhinal cortex by lateral inputs in hippocampal granule cells
The medial dendrites (MDs) of granule cells (GCs) receive spatial information through the medial entorhinal cortex (MEC) from the entorhinal cortex...
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A transformer-based representation-learning model with unified processing of multimodal input for clinical diagnostics
During the diagnostic process, clinicians leverage multimodal information, such as the chief complaint, medical images and laboratory test results....
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Cerebellar plasticity-based equalization of total input to inferior olive cells: properties of the model dynamics
The results of computational experiments with the biologically plausible cerebellar model are presented. First, the model convergence is examined...
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A dynamic neural field model of continuous input integration
The ability of neural systems to turn transient inputs into persistent changes in activity is thought to be a fundamental requirement for higher...
