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Influenza A Virus: Cellular Entry
The frequent emergence of pathogenic viruses with pandemic potential has posed a significant threat to human health and economy, despite enormous... -
Evaluation of the fully automated, sample-to-result Seegene STARlet-AIOS platform for detection of SARS-CoV-2, influenza virus A, influenza virus B, and RSV
Early, accurate, and bulk detection of respiratory pathogens is essential for patient management and infection control. STARlet-All-in-One System...
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A mosaic influenza virus-like particles vaccine provides broad humoral and cellular immune responses against influenza A viruses
The development of a universal influenza vaccine to elicit broad immune responses is essential in reducing disease burden and pandemic impact. In...
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Influenza A Virus Neuraminidase Inhibitors
Depending on the strain, influenza A virus causes animal, zoonotic, pandemic, or seasonal influenza with varying degrees of severity. Two surface... -
Defining the balance between optimal immunity and immunopathology in influenza virus infection
Influenza A viruses remain a global threat to human health, with continued pandemic potential. In this Review, we discuss our current understanding...
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Attenuation of A(H7N9) influenza virus infection in mice exposed to cigarette smoke
Influenza A(H7N9) virus showed high pathogenicity in humans when it emerged in 2013. Cigarette smoke (CS) causes pulmonary diseases including...
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Clinical characteristics of outpatients with influenza-B-associated pneumonia and molecular evolution of influenza B virus in Bei**g, China, during the 2021–2022 influenza season
We analyzed the clinical characteristics of outpatients with influenza-B-associated pneumonia during the 2021–2022 influenza season and analyzed the...
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Influenza Virus Entry inhibitors
Influenza is a major challenge to health and the global economy. However, the increasing emergence of drug resistance during influenza pandemics... -
A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and...
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Expression of the SARS-CoV-2 receptor-binding domain by live attenuated influenza vaccine virus as a strategy for designing a bivalent vaccine against COVID-19 and influenza
Influenza and SARS-CoV-2 are two major respiratory pathogens that cocirculate in humans and cause serious illness with the potential to exacerbate...
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A protective measles virus-derived vaccine inducing long-lasting immune responses against influenza A virus H7N9
A novel Influenza A virus (subtype H7N9) emerged in spring 2013 and caused considerable mortality in zoonotically infected patients. To be prepared...
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Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge
Current Influenza virus vaccines primarily induce antibody responses against variable epitopes in hemagglutinin (HA), necessitating frequent updates....
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Effects and mechanism of Qingke **chuan granules against influenza virus infection
Qingke **chuan granules (QPGs), which contain Houttuynia cordata Thunb, Fritillaria cirrhosa , fired licorice, and fired bitter almonds, among other...
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Phillyrin ameliorates influenza a virus-induced pulmonary inflammation by antagonizing CXCR2 and inhibiting NLRP3 inflammasome activation
Influenza is an acute viral respiratory illness with high morbidity rates worldwide. Excessive pulmonary inflammation is the main characteristic of...
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A novel film spray containing curcumin inhibits SARS-CoV-2 and influenza virus infection and enhances mucosal immunity
BackgroundInfection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and influenza virus is still a major worldwide health concern....
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Cholesterol and M2 Rendezvous in Budding and Scission of Influenza A Virus
The cholesterol of the host cell plasma membrane and viral M2 protein plays a crucial role in multiple stages of infection and replication of the... -
H6N2 reassortant avian influenza virus isolate in wild birds in Jiangxi Province, China
H6 avian influenza virus is widely prevalent in wild birds and poultry and has caused human infection in 2013 in Taiwan, China. During our active...
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Advancing usability of an influenza hemagglutinin virus-like particle vaccine expressing a chimeric cytokine
Vaccine efficacy of conventional influenza vaccines depend on the antigenic similarity between the selected vaccine strain and annual epidemic...
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Influenza from a One Health Perspective: Infection by a Highly Versatile Virus
Influenza A viruses (IAVs) are among the most versatile viruses, in terms of host range, pathogenesis, route of transmission, transmissibility... -
Immune response in influenza virus infection and modulation of immune injury by viral neuraminidase
Influenza A viruses cause severe respiratory illnesses in humans and animals. Overreaction of the innate immune response to influenza virus infection...