Search
Search Results
-
Vertical transmission of hepatitis B virus from father to child: what can be concluded about this possibility?
Vertical hepatitis B virus (HBV) transmission is defined as transmission that occurs during pregnancy or postpartum from an HBV-infected mother to...
-
Exploring the global immune landscape of peripheral blood mononuclear cells in H5N6-infected patient with single-cell transcriptomics
BackgroundAvian influenza viruses (AIV), particularly H5N6, have risen in infection frequency, prompting major concerns. Single-cell RNA sequencing...
-
Length of Leukocyte Telomeres in Newborns of HIV-Infected Mothers
We studied the relative length of telomeres in newborns with unrealized perinatal transmission of HIV (zero viral load according to PCR results). A...
-
Human Trypanosoma cruzi infection in the Argentinean Chaco: risk factors and identification of households with infected children for treatment
BackgroundChagas disease is a neglected tropical disease (NTD). Cost-effective strategies for large-scale implementation of diagnosis and etiological...
-
Real-world implementation of a multilevel interventions program to prevent mother-to-child transmission of HBV in China
Reducing hepatitis B virus (HBV) mother-to-child transmission (MTCT) is a fundamental step toward the HBV elimination goal. The multicentred,...
-
Case report: hepatitis in a child infected with SARS-CoV-2 presenting toll-like receptor 7 Gln11Leu single nucleotide polymorphism
BackgroundCovid-19 has the respiratory tract as the main target of infection, and patients present mainly dyspnea, pneumonia, dry cough, and fever....
-
Leveraging antigenic seniority for maternal vaccination to prevent mother-to-child transmission of HIV-1
The development of a maternal HIV vaccine to synergize with current antiretroviral drug prophylaxis can overcome implementation challenges and...
-
Association of TREX1 polymorphism with disease progression in human immunodeficiency virus type-1 (HIV-1) infected patients
The time interval between HIV-1 infection and AIDS development is not the same in all patients and depends largely on the genetic background of the...
-
Persistent accelerated epigenetic ageing in a longitudinal cohort of vertically infected HIV-positive adolescents
We have previously shown accelerated ageing in adolescents perinatally infected with HIV (PHIV +), based on discrepancies between epigenetic and...
-
Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan
CD8 + T cells provide robust antiviral immunity, but how epitope-specific T cells evolve across the human lifespan is unclear. Here we defined CD8 + T...
-
Investigation of urine metabolome of BALB/c mouse infected with an avirulent strain of Toxoplasma gondii
BackgroundThe protozoan parasite Toxoplasma gondii is a major concern for human and animal health. Although the metabolic understanding of...
-
A child-friendly anti-infective gummy formulation: Design, physicochemical, micromechanical, and taste sensory evaluation
The shortage of child friendly formulations constitutes a key part of the major challenges impeding the successful management of tuberculosis disease...
-
The Pampa del Indio project: sustainable vector control and long-term declines in the prevalence and abundance of Triatoma infestans infected with Trypanosoma cruzi in the Argentine Chaco
BackgroundThe Gran Chaco region is a major hotspot of Chagas disease. We implemented a 9-year program aimed at suppressing house infestation with Tria...
-
Reduced neuronal population in the dorsolateral prefrontal cortex in infant macaques infected with simian immunodeficiency virus (SIV)
Pediatric HIV infection remains a global health crisis with an estimated 150,000 new mother-to-child (MTCT) infections each year. Antiretroviral...
-
The presence of human respiratory syncytial virus in the cerebrospinal fluid of a child with Anti-N-methyl-D-aspartate receptor encephalitis of unknown trigger
BackgroundAnti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an important type of brain inflammation caused by autoantibody. As one of...
-
Bone marrow stromal antigen 2 (BST-2) genetic variants influence expression levels and disease outcome in HIV-1 chronically infected patients
BackgroundBone marrow stromal antigen 2 (BST-2) also known as Tetherin (CD317/HM1.24), is a host restriction factor that blocks the release of HIV-1...
-
French national epidemiology of bacterial superinfections in ventilator-associated pneumonia in patients infected with COVID-19: the COVAP study
BackgroundDescription and comparison of bacterial characteristics of ventilator-associated pneumonia (VAP) between critically ill intensive care unit...
-
-
R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini
Racemic praziquantel (PZQ) is the standard treatment for schistosomiasis and liver fluke infections (opisthorchiasis and clonorchiasis). The...
-
Characterization of replication and variations in genome segments of a bat reovirus, BatMRV/B19-02, by RNA-seq in infected Vero-E6 cells
Mammalian orthoreoviruses (MEVs) that can cause enteric, respiratory, and encephalitic infections have been identified in a wide variety of mammalian...
