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The impact of incident stroke on cognitive trajectories in later life
BackgroundCognitive impairment is common after stroke, and a large proportion of stroke patients will develop dementia. However, there have been few...
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Incident traumatic spinal cord injury and risk of Alzheimer’s disease and related dementia: longitudinal case and control cohort study
Study designRetrospective case/control longitudinal cohort study
ObjectivesPrevalent traumatic spinal cord injury (TSCI) is associated with...
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Habitual glucosamine use, APOE genotypes, and risk of incident cause-specific dementia in the older population
BackgroundThe relationship of glucosamine use with incident dementia in the older population remains uncertain. We aimed to evaluate the longitudinal...
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Associations of resting heart rate with incident dementia, cognition, and brain structure: a prospective cohort study of UK biobank
BackgroundResting heart rate (RHR) has been linked with an increased risk of dementia. However, evidence characterizing the associations of RHR with...
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Chronic atrophic gastritis and risk of incident upper gastrointestinal cancers: a systematic review and meta-analysis
BackgroundPrevious literature has explored the relationship between chronic atrophic gastritis (CAG) and isolated cancers within the upper...
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Kidney function, albuminuria, and their modification by genetic factors and risk of incident dementia in UK Biobank
BackgroundAssociations between kidney function and dementia risk are inconclusive. Chronic kidney disease (CKD) severity is determined by levels of...
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Association of risk of incident acne and treatment with systemic Janus kinase inhibitors in atopic dermatitis: a systematic review and meta-analysis
IntroductionThe therapeutic efficacy of systemic Janus kinase (JAK) inhibitors in moderate-to-severe atopic dermatitis (AD) is well established....
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Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease
BackgroundDNA methylation clocks emerged as a tool to determine biological aging and have been related to mortality and age-related diseases. Little...
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Associations of habitual glucosamine supplementation with incident gout: a large population based cohort study
ObjectivesThe association between habitual glucosamine use and incident gout has not been examined in previous studies. We aimed to evaluate the...
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Outdoor air pollution and risk of incident adult haematologic cancer subtypes in a large US prospective cohort
BackgroundOutdoor air pollution and particulate matter (PM) are classified as Group 1 human carcinogens for lung cancer. Pollutant associations with...
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Incident type 2 diabetes attributable to suboptimal diet in 184 countries
The global burden of diet-attributable type 2 diabetes (T2D) is not well established. This risk assessment model estimated T2D incidence among adults...
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Incident Kaposi sarcoma during the expansion of antiretroviral therapy eligibility in Nigeria: a retrospective cohort study
IntroductionThe expansion of antiretroviral therapy (ART) eligibility could lead to earlier initiation of Human Immunodeficiency Virus (HIV)...
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An Investigation into the Relationship of Circulating Gut Microbiome Molecules and Inflammatory Markers with the Risk of Incident Dementia in Later Life
The gut microbiome may be involved in the occurrence of dementia primarily through the molecular mechanisms of producing bioactive molecules and...
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Polygenic scores for longitudinal prediction of incident type 2 diabetes in an ancestrally and medically diverse primary care physician network: a patient cohort study
BackgroundThe clinical utility of genetic information for type 2 diabetes (T2D) prediction with polygenic scores (PGS) in ancestrally diverse,...
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Circulating markers of oxidative stress and risk of incident cardiovascular events in obstructive sleep apnea
The identification of which patients with obstructive sleep apnea (OSA) are more likely to develop cardiovascular disease (CVD) remains a challenge....
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Medication incident recovery and prevention utilising an Australian community pharmacy incident reporting system: the QUMwatch study
PurposeTo identify factors in community pharmacy that facilitate error recovery from medication incidents (MIs) and explore medication safety...
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Non-linear relationship between the body roundness index and incident type 2 diabetes in Japan: a secondary retrospective analysis
BackgroundBody roundness index (BRI) is one of the obesity-related anthropometric indices. However, studies on the relationship between BRI and...
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Serum trimethylamine-N-oxide is associated with incident type 2 diabetes in middle-aged and older adults: a prospective cohort study
BackgroundThe role of trimethylamine-N-oxide (TMAO) in the development of diabetes remains controversial, and prospective data are few. We aimed to...
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Associations between serum glucose, insulin, insulin resistance and the risk of incident primary liver cancer or chronic liver disease mortality: a nested case–control study
BackgroundTo evaluate the associations between pre-diagnostic levels of serum insulin, glucose and insulin resistance (HOMA-IR) and future risk of...
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Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort
Human genetic variation affects the gut microbiota through a complex combination of environmental and host factors. Here we characterize genetic...