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1. Isoflurane Preconditioning Alleviates Hypoxia/Reoxygenation-Induced Cardiomyocyte Injury by Inhibiting miR-195-3p Expression

   To investigate the role of microRNA-195-3p (miR-195-3p) in hypoxia/reoxygenation (H/R)-induced cardiomyocyte injury. AC16 human cardiomyocyte cells...

   **aofei Han, Hongyuan Kan, ... **nyu Yao in Cardiovascular Toxicology

   Article 08 May 2024
   

2. miR-652-3p Suppressed the Protective Effects of Isoflurane Against Myocardial Injury in Hypoxia/Reoxygenation by Targeting ISL1

   This research is concentrated on investigating the role and mechanism of miR-652-3p in the protective effects of isoflurane (ISO) against myocardial...

   Kaikai Qi, Fang Cao, ... Guohua Li in Cardiovascular Toxicology

   Article 27 May 2024
   

3. Protective Effect of Sevoflurane Preconditioning on Cardiomyocytes Against Hypoxia/Reoxygenation Injury by Modulating Iron Homeostasis and Ferroptosis

   To investigate the mechanism whereby sevoflurane (Sev) protects cardiomyocytes from hypoxia/reoxygenation (H/R) injury. The rat cardiomyocyte line...

   Hongguang Sheng, Jun **ong, Danying Yang in Cardiovascular Toxicology

   Article 17 February 2023
   

4. HSP70 protects H9C2 cells from hypoxia and reoxygenation injury through STIM1/IP3R

   Hypoxia/reoxygenation (H/R) is used as an in vivo model of ischemia/reperfusion injury, and myocardial ischemia can lead to heart disease. Calcium...

   TianYu Liu, Zhaodong Juan, ... ZhongDong Sun in Cell Stress and Chaperones

   Article Open access 16 July 2022
   

5. The Temporal and Spatial Changes of Autophagy and PI3K Isoforms in Different Neural Cells After Hypoxia/Reoxygenation Injury

   There are limited therapeutic options for patient with traumatic spinal cord injury (SCI). Phosphoinositide 3-kinase family (PI3Ks) are the key...

   Duo Zhang, Xuanyu Chen, ... Chenxi Li in Molecular Neurobiology

   Article 14 June 2023
   

6. Isoflurane Preconditioning May Attenuate Cardiomyocyte Injury Induced by Hypoxia/Reoxygenation Possibly by Regulating miR-363-3p

   This study attempted to explore whether miR-363-3p play a role in the isoflurane (ISO)-mediated protective effect of cardiomyocyte injury induced by...

   Yanhu Ge, Chengbin Wang, ... Jun Ma in Neurotoxicity Research

   Article 12 October 2022
   

7. ENPP2 alleviates hypoxia/reoxygenation injury and ferroptosis by regulating oxidative stress and mitochondrial function in human cardiac microvascular endothelial cells

   This study aimed to elucidate the molecular mechanisms of hypoxia/reoxygenation (H/R) injury in human cardiac microvascular endothelial cells...

   Guanhua Fang, Yanming Shen, Dongshan Liao in Cell Stress and Chaperones

   Article Open access 13 April 2023
   

8. The Role of δ₂-Opioid Receptors in the Regulation of Tolerance of Isolated Cardiomyocytes to Hypoxia and Reoxygenation

   Hypoxia (20 min) and reoxygenation (30 min) were simulated on isolated rat cardiomyocytes to evaluate the cytoprotective effect of selective δ ₂ -opioid...

   A. V. Mukhomedzyanov, S. V. Popov, ... L. N. Maslov in Bulletin of Experimental Biology and Medicine

   Article 01 February 2024

9. LncRNA RNA ROR Aggravates Hypoxia/Reoxygenation-Induced Cardiomyocyte Ferroptosis by Targeting miR-769-5p/CBX7 Axis

   Ferroptosis is a new way of cell death which is reported to participate in the pathology of myocardial ischemia–reperfusion (MI/R) injury, but it's...

   Guorong Lai, Jie Shen, ... Ying** Liang in Biochemical Genetics

   Article 29 December 2023
   

10. Current Updates on Potential Role of Flavonoids in Hypoxia/Reoxygenation Cardiac Injury Model

    Clinically, timely reperfusion strategies to re-establish oxygenated blood flow in ischemic heart diseases seem to salvage viable myocardium...

    Shafreena Shaukat Ali, Liza Noordin, ... Wan Amir Nizam Wan Ahmad in Cardiovascular Toxicology

    Article 10 June 2021
    

11. Isoflurane Alleviates Myocardial Injury Induced by Hypoxia/Reoxygenation by Regulating miR-18a-5p

    The protective effect and mechanism of isoflurane on myocardial injury was investigated by constructing in vitro hypoxia/reoxygenation (HR) cell...

    Yujie Su, Guoqing Chen, ... **angmei Gao in Cardiovascular Toxicology

    Article 28 June 2021
    

12. Knockdown of circRNA-Memo1 Reduces Hypoxia/Reoxygenation Injury in Human Brain Endothelial Cells Through miRNA-17-5p/SOS1 Axis

    Circ-Memo1 has been proved to be upregulated in ischemia–reperfusion induced acute injury of kidney tissues. However, the potential role of...

    **ang Ren, Ying-**a **g, ... Jian-Wen Yang in Molecular Neurobiology

    Article 18 January 2022
    

13. Acetylcholine exerts cytoprotection against hypoxia/reoxygenation-induced apoptosis, autophagy and mitochondrial impairment through both muscarinic and nicotinic receptors

    Acetylcholine (ACh) has been shown to exert cardioprotection against myocardial ischemia/reperfusion (I/R) injury. However, whether ACh exerts its...

    Kannaporn Intachai, Siriporn C. Chattipakorn, ... Krekwit Shinlapawittayatorn in Apoptosis

    Article 29 January 2022
    

14. Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/Prdx3 pathway

    Background

    Myocardial ischemia/reperfusion injury (MIRI) seriously threatens the health of people. The mitochondrial dysfunction in cardiomyocytes can...

    Qingyun Tan, Wenming Dong, ... Li Gao in DARU Journal of Pharmaceutical Sciences

    Article 26 February 2024
    

15. MiR-7a-5p Attenuates Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis by Targeting VDAC1

    MicroRNA-7a-5p (miR-7a-5p) is closely related to apoptosis and plays an important role in ischemia/reperfusion (I/R) injury. Whether miR-7a-5p is...

    Hailin Lu, Jiangfeng Zhang, Feifei Xuan in Cardiovascular Toxicology

    Article 18 October 2021
    

16. Hypoxic White Matter Injury and Recovery After Reoxygenation in Adult Mice: Magnetic Resonance Imaging Findings and Histological Studies

    Cognitive dysfunction and brain white matter (WM) injury have been found in adults exposed to hypoxia. However, the mechanisms underlying these...

    Yanqiu Liu, Hong Qiao, ... Jiaxing Zhang in Cellular and Molecular Neurobiology

    Article 10 November 2022
    

17. GSK-3α aggravates inflammation, metabolic derangement, and cardiac injury post-ischemia/reperfusion

    Abstract

    Reperfusion after acute myocardial infarction further exaggerates cardiac injury and adverse remodeling. Irrespective of cardiac cell types,...

    Firdos Ahmad, Hezlin Marzook, ... Rizwan Qaisar in Journal of Molecular Medicine

    Article 14 September 2023
    

18. Proteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury

    Background

    The mitochondria and endoplasmic reticulum (ER) communicate via contact sites known as mitochondria associated membranes (MAMs). Many...

    Yi Li, Hua-bin Wang, ... Li Yang in Journal of Translational Medicine

    Article Open access 10 March 2024
    

19. Regulating NCOA4-Mediated Ferritinophagy for Therapeutic Intervention in Cerebral Ischemia-Reperfusion Injury

    Ischemic stroke presents a global health challenge, necessitating an in-depth comprehension of its pathophysiology and therapeutic strategies. While...

    Lan Zhao, Yanan Li, ... Wenwei Gao in Neurochemical Research

    Article 07 May 2024
    

20. Elucidating the role of hypoxia/reoxygenation in hippocampus-dependent memory impairment: do SK channels play role?

    Professionals and mountaineers often face the problem of reperfusion injury due to re-oxygenation, upon their return to sea-level after sojourn at...

    Manisha Kadam, Saba Perveen, ... Nilofar Khan in Experimental Brain Research

    Article 29 March 2021