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Effects of acupuncture and acupressure of the acupoint compared to the tendon on the blood circulation of human tendon in vivo
PurposeThe purpose of this study was to compare the effects of acupuncture and acupressure of acupoints on tendon blood circulation with those of...
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Addressing muscle–tendon imbalances in adult male athletes with personalized exercise prescription based on tendon strain
PurposeImbalances of muscle strength and tendon stiffness can increase the operating strain of tendons and risk of injury. Here, we used a new...
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Mechanical overload-induced release of extracellular mitochondrial particles from tendon cells leads to inflammation in tendinopathy
Tendinopathy is one of the most common musculoskeletal diseases, and mechanical overload is considered its primary cause. However, the underlying...
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Histological, Physiological and Biomechanical Effects of Low-Level Laser Therapy on Tendon Healing in Animals and Humans: A Systematic Review
Low-level Laser Therapy (LLLT) was widely used in clinical practice for tendon disorders. However, the underlying mechanisms and effectiveness of...
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Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration
Our previous work demonstrated the tendon-derived extracellular matrix (ECM) extracts as vital niches to specifically direct mesenchymal stem cells...
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miRNAs contributing to the repair of tendon injury
Tendon injury is one of the most common disorders of the musculoskeletal system, with a higher likelihood of occurrence in elderly individuals and...
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Cell Sheet Technology: An Emerging Approach for Tendon and Ligament Tissue Engineering
Tendon and ligament injuries account for a substantial proportion of disorders in the musculoskeletal system. While non-operative and operative...
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Hyperlipidemia in tendon injury: chronicles of low-density lipoproteins
Hyperlipidemia impacts millions of people globally and has been the major risk factor for develo** atherosclerosis and cardiovascular disease....
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Achilles tendon and triceps surae muscle properties in athletes
PurposeThe aim of this study was to investigate internal Achilles tendon (AT) displacement, AT shear wave velocity (SWV), and triceps surae (TS)...
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Aging Does Not Alter Ankle, Muscle, and Tendon Stiffness at Low Loads Relevant to Stance
Older adults have difficulty maintaining balance when faced with postural disturbances, a task that is influenced by the stiffness of the triceps...
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Dynamic Tensile Stress Promotes Regeneration of Achilles Tendon in a Panda Rope Bridge Technique Mice Model
Regeneration of ruptured Achilles tendon remains a clinical challenge owing to its limited regenerative capacity. Dynamic tensile stress plays a...
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Bioactive extracellular matrix fragments in tendon repair
Tendinopathy is a common tendon disorder that causes pain, loss of strength and function, and local inflammation mainly characterized by hypoxia,...
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Caveolin-1 is involved in fatty infiltration and bone-tendon healing of rotator cuff tear
BackgroundCaveolin-1 has been predicted, based on RNA transcriptome sequencing, as a key gene in rotator cuff tear (RCT) and it is related to fatty...
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Transcriptomics reveals dynamic changes in the “gene profiles” of rat supraspinatus tendon at three different time points after diabetes induction
ObjectiveThere is increasing evidence that type 2 diabetes mellitus (T2DM) is an independent risk factor for the occur of tendinopathy. Therefore,...
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Simvastatin promotes rat Achilles tendon-bone interface healing by promoting osteogenesis and chondrogenic differentiation of stem cells
To investigate the effect and mechanism of simvastatin on cell components of tendon-bone healing interface. The tendon-bone healing model was...
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Muscle Morphology Does Not Solely Determine Knee Flexion Weakness After Anterior Cruciate Ligament Reconstruction with a Semitendinosus Tendon Graft: A Combined Experimental and Computational Modeling Study
The distal semitendinosus tendon is commonly harvested for anterior cruciate ligament reconstruction, inducing substantial morbidity at the knee. The...
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Tendon and multiomics: advantages, advances, and opportunities
Tendons heal by fibrosis, which hinders function and increases re-injury risk. Yet the biology that leads to degeneration and regeneration of tendons...
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Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity
Hydrogels that provide mechanical support and sustainably release therapeutics have been used to treat tendon injuries. However, most hydrogels are...
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Increasing Vascular Response to Injury Improves Tendon Early Healing Outcome in Aged Rats
Tendon injuries positively correlate with patient age, as aging has significant effects on tendon homeostatic maintenance and healing potential after...
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Tendinopathy: sex bias starts from the preclinical development of tendon treatments. A systematic review
Tendinopathies are common overuse disorders that arise both in athletes and the general population. Available tendon treatments are used both for...
