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  1. Lipid droplets in pathogen infection and host immunity

    As the hub of cellular lipid metabolism, lipid droplets (LDs) have been linked to a variety of biological processes. During pathogen infection, the...

    Yan-jie Tan, Yi **, ... Yun-fan Yang in Acta Pharmacologica Sinica
    Article 22 November 2023
  2. An entomopathogenic fungus exploits its host humoral antibacterial immunity to minimize bacterial competition in the hemolymph

    Background

    The insect hemolymph (blood-equivalent fluid), composed of a large number of hemocytes (blood cells) and a variety of soluble immune...

    Jia-Lin Wang, **g Sun, ... Xu-Sheng Liu in Microbiome
    Article Open access 20 May 2023
  3. Immunity

    The term immunity is derived from the Latin word “immunis” (exempt), which originally referred to the protection from legal prosecution offered to...
    Subhash Chandra Parija in Textbook of Microbiology and Immunology
    Chapter 2023
  4. The molecular mechanism of SARS-CoV-2 evading host antiviral innate immunity

    The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a global health emergency (COVID-19) because of its...

    Wen**g Gu, Hui Gan, ... Chuangli Hao in Virology Journal
    Article Open access 19 March 2022
  5. Human Monkeypox Virus and Host Immunity: New Challenges in Diagnostics and Treatment Strategies

    The monkeypox virus (MPXV), responsible for human disease, has historically been limited to the African countries, with only a few isolated instances...
    Shailendra Dwivedi, Vijay Singh, ... Sanjeev Misra in Poxviruses
    Chapter 2024
  6. Clinical characteristics and host immunity responses of SARS-CoV-2 Omicron variant BA.2 with deletion of ORF7a, ORF7b and ORF8

    Background

    The pathogenicity and virulence of the Omicron strain have weakened significantly pathogenesis of Omicron variants. Accumulating data...

    Zhizhong Tang, Pei Yu, ... Tianxing Ji in Virology Journal
    Article Open access 29 May 2023
  7. Immunity, Immunity, Immunity

    Immunity is critical for survival from all infectious pathogens, including viruses. The three types of immunity (intrinsic, innate, and adaptive)...
    Van G. Wilson in Viruses: Intimate Invaders
    Chapter 2022
  8. Regulation of Host Immunity by the Gut Microbiota

    Constant exposure to diverse microorganisms has accompanied human evolution and continues to shape immunological development throughout life. In...
    Chapter 2022
  9. Monkeypox: disease epidemiology, host immunity and clinical interventions

    Monkeypox virus (MPXV), which causes disease in humans, has for many years been restricted to the African continent, with only a handful of sporadic...

    Fok-Moon Lum, Anthony Torres-Ruesta, ... Lisa F. P. Ng in Nature Reviews Immunology
    Article 05 September 2022
  10. Echinococcosis Immune Response, Immunopathogenesis and Immune Evasion from the Human Host

    Echinococcosis is a worldwide parasitic disease with great harm and complicated immune mechanisms. Immunoprophylaxis is an ideal way to prevent...
    Chapter 2024
  11. Skin Microbiome and Host Immunity: Applications in Regenerative Cosmetics and Transdermal Drug Delivery

    Recent advances in our understanding of the function of the skin and its microbiome have shown that there is a strong symbiotic relationship between...
    Chapter 2022
  12. Host-Directed Antiviral Therapy

    Most of the antiviral drugs developed so far have been specifically designed to target particular pathogens and their unique viral pathways. However,...
    Joyshikh Sonowal, Rajib Deb, ... Vivek Kumar Gupta in Advances in Antiviral Research
    Chapter 2024
  13. SARS-CoV-2 Infection: Host Response, Immunity, and Therapeutic Targets

    Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a global...

    Pooja Shivshankar, Harry Karmouty-Quintana, ... **aoyi Yuan in Inflammation
    Article 23 March 2022
  14. Nutritional Immunity and Fungal Pathogens: A New Role for Manganese

    Purpose of Review

    Copper, zinc, iron, and manganese are essential micronutrients for all living organisms. Microbial pathogens must acquire these...

    Asia S. Wildeman, Valeria C. Culotta in Current Clinical Microbiology Reports
    Article 20 March 2024
  15. Evasion and Suppression of Immunity

    Pathogens must evade or suppress the host’s immune system to persist. Immune evasion refers to passive evasion and active suppression of immune...
    Michael G. Milgroom in Biology of Infectious Disease
    Chapter 2023
  16. Tissue-specific immunity in helminth infections

    A characteristic feature of host responses to helminth infections is the development of profound systemic and tissue-localised Type 2 immune...

    Francesco Vacca, Graham Le Gros in Mucosal Immunology
    Article 09 June 2022
  17. The role of plasmacytoid dendritic cells (pDCs) in immunity during viral infections and beyond

    Type I and III interferons (IFNs) are essential for antiviral immunity and act through two different but complimentary pathways. First, IFNs activate...

    Clémence Ngo, Clémence Garrec, ... Marc Dalod in Cellular & Molecular Immunology
    Article Open access 22 May 2024
  18. Innate Immunity

    Reference work entry 2024
  19. Innate Immunity and Inflammation

    In this chapter, we will explain that the innate immune system has effector functions that allow a very early response to invading pathogens as well...
    Carsten Carlberg, Eunike Velleuer, Ferdinand Molnár in Molecular Medicine
    Chapter 2023
  20. Viruses, SUMO, and immunity: the interplay between viruses and the host SUMOylation system

    The conjugation of small ubiquitin-like modifier (SUMO) proteins to substrates is a well-described post-translational modification that regulates...

    Fergan Imbert, Dianne Langford in Journal of NeuroVirology
    Article 03 August 2021
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