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Mitochondrial transfer in hematological malignancies
Mitochondria are energy-generated organelles and take an important part in biological metabolism. Mitochondria could be transferred between cells,...
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SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities
Hematological malignancies are a highly heterogeneous group of diseases with varied molecular and phenotypical characteristics. SWI/SNF...
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Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults
Over one million European children undergo computed tomography (CT) scans annually. Although moderate- to high-dose ionizing radiation exposure is an...
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Cytogenetic culture failure and its causes in hematological disorders; a single centre perspective
ObjectiveTo highlight the reasons of culture failure in bone marrow aspirate samples sent for Cytogenetic analysis and to identify the associated...
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Flow Cytometry in the Diagnosis of Hematological Neoplasms and Other Cancers
Flow cytometry (FCM) is a powerful technology that can provide rapid multiparameter analysis of single cells. With the significant improvement in... -
One-year breakthrough SARS-CoV-2 infection and correlates of protection in fully vaccinated hematological patients
The long-term clinical efficacy of SARS-CoV-2 vaccines according to antibody response in immunosuppressed patients such as hematological patients has...
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Financial toxicity in hematological malignancies: a systematic review
Hematologic malignancy outcomes have remarkably improved in the past decade with further advancement expected in future years. However, the...
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Deubiquitinases in hematological malignancies
Deubiquitinases (DUBs) are enzymes that control the stability, interactions or localization of most cellular proteins by removing their ubiquitin...
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Immune biomarkers to predict SARS-CoV-2 vaccine effectiveness in patients with hematological malignancies
There is evidence of reduced SARS-CoV-2 vaccine effectiveness in patients with hematological malignancies. We hypothesized that tumor and...
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Detection and genetic characterization of feline retroviruses in domestic cats with different clinical signs and hematological alterations
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are globally distributed retroviruses that infect domestic cats and cause...
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The landscape overview of CD47-based immunotherapy for hematological malignancies
Extensive clinical and experimental evidence suggests that macrophages play a crucial role in cancer immunotherapy. Cluster of differentiation (CD)...
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The emerging landscape of exosomal CircRNAs in solid cancers and hematological malignancies
Circular RNAs (circRNAs) are a type of recently discovered noncoding RNA. They exert their biological functions by competitively binding to microRNAs...
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When Glycosylation Meets Blood Cells: A Glance of the Aberrant Glycosylation in Hematological Malignancies
Among neoplasia-associated epigenetic alterations, changes in cellular glycosylation have recently received attention as a key component of... -
Characterizing the polygenic architecture of complex traits in populations of East Asian and European descent
To investigate the polygenicity of complex traits in populations of East Asian (EAS) and European (EUR) descents, we leveraged genome-wide data from...
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Hyaluronan in the Extracellular Matrix of Hematological and Solid Tumors. Its Biological Effects
Tumors are most frequently induced by environmental factors with oncogenic potential. Beside tumor cells, cancer tissue contains several nonmalignant... -
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Long-term follow-up of cladribine treatment in hairy cell leukemia: 30-year experience in a multicentric Italian study
Hairy cell leukemia (HCL) is a rare lymphoproliferative disease with an excellent prognosis after treatment with cladribine (2CDA), although relapse...
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T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy
We report a T cell lymphoma (TCL) occurring 3 months after anti-CD19 chimeric antigen receptor (CAR) T cell immunotherapy for non-Hodgkin B cell...