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Structural basis for pathogenic variants of GJB2 and hearing levels of patients with hearing loss
ObjectivesThe crystal structure of the six protomers of gap junction protein beta 2 (GJB2) enables prediction of the effect(s) of an amino acid...
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A History of Discoveries on Hearing
This volume focuses on the history of research on hearing from comparative approaches. Each chapters examines the most formative studies that led to...
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Insect Hearing: Selected Historical Vignettes
How insects hear has understandably been influenced by what we know about how vertebrates hear. However, insects are among the smallest of...
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The congenital hearing phenotype in GJB2 in Queensland, Australia: V37I and mild hearing loss predominates
GJB2 was originally identified in severe, non-syndromic sensorineural hearing loss (SNHL), but was subsequently associated with mild and moderate...
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Diabetes mellitus and hearing loss
Diabetes mellitus (DM) is a major disease threatening human health and its incidence is increasing year on year. As a chronic complication of DM,...
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Discoveries in Marine Mammal Hearing
Early studies of marine mammals underwater were driven by awe, imagination, and the wealth they represented from oil, bone, and flesh. Aristotle...
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A systematic review on the contribution of DNA methylation to hearing loss
BackgroundDNA methylation may have a regulatory role in monogenic sensorineural hearing loss and complex, polygenic phenotypic forms of hearing loss,...
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Birds as a Model in Hearing Research
The earliest reference to hearing birds can be traced back to Aristotle who mused about the parallels between birdsong and human language, a theme...
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Genetic analysis of 106 sporadic cases with hearing loss in the UAE population
BackgroundHereditary hearing loss is a rare hereditary condition that has a significant presence in consanguineous populations. Despite its...
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Experimental Approaches to the Study of Sound Source Localization by Distance in Hearing Pathology
This paper presents an overview of current experimental approaches used to assess the ability to localize sound sources by distance in hearing...
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Investigating the impact of hearing loss on attentional networks among older individuals: an event-related potential study
Attention is a core cognitive domain crucial in facilitating day-to-day life. Using an attention network test (ANT) along with event-related...
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Evolution of the Understanding of Fish Hearing
Several ancient scholars assumed that fishes could hear, but it was not until early in the twentieth century that this was clearly demonstrated. At...
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Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study
BackgroundHearing loss has been shown to be a risk factor for psychiatric disorders. In addition, long-term hearing loss is associated with increased...
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Epidemiologic association and shared genetic architecture between cataract and hearing difficulties among middle-aged and older adults
Age-related cataract and hearing difficulties are major sensory disorders that often co-exist in the global-wide elderly and have a tangible...
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A History of Discoveries on Hearing: An Overview
This volume, unlike all past volumes in the Springer Handbook of Auditory Research (SHAR) series, recounts the history of the science of and research...
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Overlooked KCNQ4 variants augment the risk of hearing loss
Pathogenic variants of KCNQ4 cause symmetrical, late-onset, progressive, high-frequency-affected hearing loss, which eventually involves all...
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Dispersed DNA variants underlie hearing loss in South Florida’s minority population
BackgroundWe analyzed the genetic causes of sensorineural hearing loss in racial and ethnic minorities of South Florida by reviewing demographic,...
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The neuroanatomical hallmarks of chronic tinnitus in comorbidity with pure-tone hearing loss
Tinnitus is one of the main hearing impairments often associated with pure-tone hearing loss, and typically manifested in the perception of phantom...
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Prediction of pure tone thresholds using the speech reception threshold and age in elderly individuals with hearing loss
ObjectiveEarly detection and effective management of hearing loss constitute the key to improving the quality of life of individuals with hearing...
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The natural history, clinical outcomes, and genotype–phenotype relationship of otoferlin-related hearing loss: a systematic, quantitative literature review
Congenital hearing loss affects one in 500 newborns. Sequence variations in OTOF , which encodes the calcium-binding protein otoferlin, are...
