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Dietary Supplementation Strategies for Improving Training Adaptations, Antioxidant Status and Performance of Volleyball Players: A Systematic Review
PurposeVolleyball demands high physical performance including agility, speed, endurance and muscular strength. As volleyball players explore methods...
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Pitfalls in Cutaneous Melanoma Diagnosis and the Need for New Reliable Markers
Cutaneous melanoma is one of the most aggressive forms of skin cancer, with the development of advanced stage disease resulting in a high rate of...
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Simultaneous endocrine expression and loss of melanoma markers in malignant melanoma metastases, a retrospective analysis
Malignant melanoma metastases are chameleons of histopathology. In 4 primary malignant melanomas and 20 melanoma metastases expression of S-100,...
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The function of γδ T cells in humoral immune responses
PurposeThe purpose of this review is to discuss the role of γδ T cells played in humoral immune responses.
BackgroundThe γδ T cell receptor (γδ TCR)...
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Therapy-Induced Toxicities Associated with the Onset of Cachexia
Cancer is the second-leading cause of death worldwide. Notably, 40% of all patients suffer from cachexia, a debilitating muscle wasting syndrome that...
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Executive summary of the 14th HHT international scientific conference
Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant vascular disorder characterized by small, dilated clustered vessels...
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Intracranial mesenchymal tumor with (novel) COX14::PTEN rearrangement
Mesenchymal tumors of the central nervous system (CNS) include numerous entities, with different pathological features and biological behavior....
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Sex-dependent variation in cartilage adaptation: from degeneration to regeneration
Despite acknowledgement in the scientific community of sex-based differences in cartilage biology, the implications for study design remain unclear,...
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Pathologic Assessment of Lymph Node Metastasis
The pathologic assessment and evaluation of lymph node status plays a central role in the diagnosis, staging, and management of most malignancies....
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Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness
BackgroundMucosal Melanomas (MM) are highly aggressive neoplasms arising from mucosal melanocytes. Current treatments offer a limited survival...
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Immunohistochemical Staining in the Assessment of Melanoma Tumor Thickness
Vertical tumor thickness has great influence in the prognosis and staging of melanoma. The aim of this study was determination of the differences...
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Unsupervised representation learning on high-dimensional clinical data improves genomic discovery and prediction
Although high-dimensional clinical data (HDCD) are increasingly available in biobank-scale datasets, their use for genetic discovery remains...
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Metabolic flux between organs measured by arteriovenous metabolite gradients
Mammalian organs convert dietary nutrients into circulating metabolites and share them to maintain whole-body metabolic homeostasis. While the...
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Health care systems administrators perspectives on antimicrobial stewardship and infection prevention and control programs across three healthcare levels: a qualitative study
IntroductionAntimicrobial stewardship (AMS) and infection prevention control (IPC) programs are proposed to address antimicrobial resistance....
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Genetic alteration of Chinese patients with rectal mucosal melanoma
BackgroundRectal mucosal melanoma (RMM) is a rare and highly aggressive disease with a poor prognosis. Due to the rarity of RMM, there are few...
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Regional Onco-Sphere: Lymph Node Metastasis
During cancer metastasis, cancer cells spread by dissemination into nearby normal tissue mostly via two major routes (i) lymph nodes and (ii) blood...
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Missense mutation of NRAS is associated with malignant progression in neurocutaneous melanosis
Neurocutaneous melanosis (NCM) is a rare congenital neurocutaneous syndrome characterized by congenital melanocytic nevus of skin and abnormal...
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Inoculation of mother’s own milk could personalize pasteurized donor human milk used for feeding preterm infants
BackgroundHuman milk is a vehicle for bioactive compounds and beneficial bacteria which promote the establishment of a healthy gut microbiome of...
