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Focal HDR brachytherapy boost to stereotactic radiotherapy (fBTsRT) for prostate cancer: a phase II randomized controlled trial
BackgroundFor patients with a higher burden of localized prostate cancer, radiation dose escalation with brachytherapy boosts have improved cancer...
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Brachytherapy for targeting the immune system in cervical cancer patients
BackgroundNew combinations based on standard therapeutic modalities and immunotherapy require understanding the immunomodulatory properties of...
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A review of dosimetric impact of implementation of model-based dose calculation algorithms (MBDCAs) for HDR brachytherapy
To obtain dose distributions more physically representative to the patient anatomy in brachytherapy, calculation algorithms that can account for...
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Review of brachytherapy clinical trials: a cross-sectional analysis of ClinicalTrials.gov
IntroductionCharacterizing the landscape of clinical trials including brachytherapy can provide an overview of the current status and research trends...
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The use of Lutetium-177 PSMA radioligand therapy with high dose rate brachytherapy for locally recurrent prostate cancer after previous definitive radiation therapy: a randomized, single-institution, phase I/II study (ROADSTER).
BackgroundIsolated local failure (ILF) can occur in patients who initially receive definitive radiation therapy for prostate cancer. Salvage therapy...
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Low-dose-rate brachytherapy as a primary treatment for localised and locally advanced prostate cancer: a systematic review of economic evaluations
BackgroundThis study supports a value-based approach to prostate cancer (PCa) treatment by systematically reviewing economic evaluations that compare...
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Comparison of liver exposure in CT-guided high-dose rate (HDR) interstitial brachytherapy versus SBRT in hepatocellular carcinoma
BackgroundIn unresectable hepatocellular carcinoma several local ablative treatments are available. Among others, radiation based treatments such as...
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Radiobiological and dosimetric comparison of 60Co versus 192Ir high-dose-rate intracavitary-interstitial brachytherapy for cervical cancer
BackgroundHigh-dose-rate (HDR) intracavitary-interstitial brachytherapy (IC-ISBT) is an effective treatment for bulky, middle, and advanced cervical...
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Analysis of a cohort of prostate patients treated with HDR mono-brachytherapy
The aim of this study is to perform volumetric and basic radiobiological analyses using the database on prostate patients treated by HDR...
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A dosimetric comparison of CT- and photogrammetry- generated 3D printed HDR brachytherapy surface applicators
In this study, we investigate whether an acceptable dosimetric plan can be obtained for a brachytherapy surface applicator designed using...
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The MRI-guided two adaptive brachytherapy fractions versus one adaptive brachytherapy fraction in one application for the cervical cancer: a retrospective study
PurposeThis study retrospectively compared the clinical and toxicity outcomes for the cervical cancer of the MRI-guided two adaptive brachytherapy...
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Circulating miR-21 as a prognostic biomarker in HCC treated by CT-guided high-dose rate brachytherapy
Background and aimsPrognostic biomarkers identifying patients with early tumor progression after local ablative therapy remain an unmet clinical...
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Being certain about uncertainties: a robust evaluation method for high-dose-rate prostate brachytherapy treatment plans including the combination of uncertainties
In high-dose-rate (HDR) prostate brachytherapy the combined effect of uncertainties cause a range of possible dose distributions deviating from the...
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Applicator-guided proton therapy versus multichannel brachytherapy for vaginal vault irradiation
To dosimetrically compare applicator-guided intensity-modulated proton therapy (IMPT) and multichannel brachytherapy (MC-BRT) for vaginal vault...
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Safety of accelerated hypofractionated whole pelvis radiation therapy prior to high dose rate brachytherapy or stereotactic body radiation therapy prostate boost
BackgroundTo evaluate acute and late genitourinary and gastrointestinal toxicities and patient reported urinary and sexual function following...
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Dose escalation in oropharyngeal cancer: a comparison of simultaneous integrated boost and brachytherapy boost
BackgroundLocal recurrence is the most common pattern of failure in head and neck cancer. It can therefore be hypothesised that some of these...
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Monte Carlo dosimetry of the 60Co sources of a new GZP3 HDR afterloading system
BackgroundThe purpose of this work was to obtain the dosimetric parameters of the new GZP3 60 Co high-dose-rate afterloading system launched by the...
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Evaluation of camera settings for photogrammetric reconstruction of humanoid phantoms for EBRT bolus and HDR surface brachytherapy applications
The fabrication of brachytherapy surface moulds is considered laborious and time consuming that often result in repeated attempts due to incorrect...
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A deep learning-based self-adapting ensemble method for segmentation in gynecological brachytherapy
PurposeFast and accurate outlining of the organs at risk (OARs) and high-risk clinical tumor volume (HRCTV) is especially important in high-dose-rate...
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The safety and efficacy of volumetric modulated Arc therapy combined with computer tomography-guided adaptive brachytherapy for locally advanced cervical cancer: a single institution experience
BackgroundVolumetric modulated arc therapy (VMAT) is a novel form of IMRT, which can deliver more accurate dose distribution and shorten treatment...
