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1. Protective role of microRNA-23a/b-3p inhibition against osteoarthritis through Gremlin1-depenent activation of TGF-β/smad signaling in chondrocytesa

   The changed biomechanical environment of chondrocytes elicited by altered extracellular matrix is reported to accelerate the progression of OA....

   **n Lu, **sheng Weng, ... Yue Huang in Inflammopharmacology

   Article 19 April 2022
   

2. Expression of the Serrated Markers Annexin A10 or Gremlin1 in Colonic Adenocarcinomas: Morphology and Prognostic Values

   Describe clinical, histological and molecular charatcteristics and prognosis values of the serrated candidate markers AnnexinA10 and Gremlin1 in...

   Benjamin Marquet, Aude Marchal Bressenot, ... Camille Boulagnon-Rombi in Pathology & Oncology Research

   Article 24 June 2020
   

3. A Novel Missense Single Nucleotide Polymorphism in the GREM1 Gene is Highly Associated with Higher Reproductive Traits in Awassi Sheep

   GREM1 (gremlin1) is a known inhibitor for BMP15 (bone morphogenetic protein 15) family, but its genetic diversity in sheep is unknown. The present...

   Faris S. Imran, Tahreer M. Al-Thuwaini, ... Frederic Lepretre in Biochemical Genetics

   Article 13 October 2020
   

4. Results from omic approaches in rat or mouse models exposed to inhaled crystalline silica: a systematic review

   Background

   Crystalline silica (cSiO ₂ ) is a mineral found in rocks; workers from the construction or denim industries are particularly exposed to cSiO ₂ ...

   Laura Morin, Valérie Lecureur, Alain Lescoat in Particle and Fibre Toxicology

   Article Open access 01 March 2024
   

5. RETRACTED ARTICLE: Knockdown of circRNA_0007534 suppresses the tumorigenesis of cervical cancer via miR-206/GREM1 axis

   Background

   Increasing evidence manifested that circular RNAs (circRNAs) acted as crucial regulators in human cancers by targeting the miRNA/mRNA axis,...

   Qiang Sun, **angying Qi, ... **aoyu Li in Cancer Cell International

   Article Open access 14 January 2021
   

6. Bone Morphogenetic Proteins

   Derek P. Brazil in Encyclopedia of Molecular Pharmacology

   Reference work entry 2021
   

7. Gremlin 1⁺ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues

   Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture and regulate lymphocyte compartmentalization,...

   Varun N. Kapoor, Sören Müller, ... Shannon J. Turley in Nature Immunology

   Article 26 April 2021
   

8. Lymphoid stromal cells proGrem dendritic cell homeostasis

   Antonio P. Baptista, Michael Y. Gerner in Nature Immunology

   Article 26 April 2021
   

9. Bone Morphogenetic Proteins

   Derek P. Brazil in Encyclopedia of Molecular Pharmacology

   Living reference work entry 2020
   

10. Evo-Devo Path as a Bridge between Evolution, Morphological Disparity, and Medicine with Comments on “Hopeful Monsters” in the Age of Genomics

    Purpose of Review

    Since its inception in the late 1970s/early 1980s, Evolutionary Developmental Biology (Evo-Devo) has produced much insight into the...

    Raul E. Diaz Jr. in Current Molecular Biology Reports

    Article 16 May 2020
    

11. ROS Signaling in Brain Tumor

    The heterogeneous cell population of the brain tumor and its microenvironment is a significant challenge to the current treatment modalities of...

    Debashmita Sarkar, Shilpee Dutt in Handbook of Oxidative Stress in Cancer: Therapeutic Aspects

    Reference work entry 2022
    

12. ROS Signaling in Brain Tumor

    The heterogeneous cell population of the brain tumor and its microenvironment is a significant challenge to the current treatment modalities of...

    Debashmita Sarkar, Shilpee Dutt in Handbook of Oxidative Stress in Cancer: Therapeutic Aspects

    Living reference work entry 2022
    

13. Advantages and Limitations of Cre Mouse Lines Used in Skeletal Research

    The Cre-LoxP technology permits gene ablation in specific cell lineages, at chosen differentiation stages of this lineage and in an inducible manner....

    Florent Elefteriou, Greig Couasnay in Skeletal Development and Repair

    Protocol 2021
    

14. Clone wars: From molecules to cell competition in intestinal stem cell homeostasis and disease

    The small intestine is among the fastest self-renewing tissues in adult mammals. This rapid turnover is fueled by the intestinal stem cells residing...

    Gabriele Colozza, So-Yeon Park, Bon-Kyoung Koo in Experimental & Molecular Medicine

    Article Open access 18 September 2022
    

15. Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications

    Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy because of their high immunomodulation ability, tropism towards...

    Wei-Zhan Zhuang, Yi-Heng Lin, ... Thai-Yen Ling in Journal of Biomedical Science

    Article Open access 14 April 2021
    

16. The miR-23–27–24 cluster: an emerging target in NAFLD pathogenesis

    The incidence of non-alcoholic fatty liver disease (NAFLD) is increasing globally, being the most widespread form of chronic liver disease in the...

    Lin Ru, **ao-mei Wang, Jun-qi Niu in Acta Pharmacologica Sinica

    Article 10 December 2021
    

17. Bone marrow adiposity during pathologic bone loss: molecular mechanisms underlying the cellular events

    Bone marrow (BM) is a heterogeneous niche where bone marrow stromal cells (BMSCs), osteoblasts, osteoclasts, adipocytes, hematopoietic cells, and...

    Jiao Li, Lingyun Lu, ... **jie Yu in Journal of Molecular Medicine

    Article 09 November 2021
    

18. LRP4 LDLα repeats of astrocyte enhance dendrite arborization of the neuron

    The low-density lipoprotein receptor-related protein 4 (LRP4) is essential for inducing the neuromuscular junction (NMJ) formation in muscle fibers,...

    Min Yan, Amin Guo, ... Shunqi Wang in Molecular Brain

    Article Open access 10 December 2020
    

19. The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation

    The main challenges in the use of immune checkpoint inhibitors (ICIs) are ascribed to the immunosuppressive tumor microenvironment and the lack of...

    Fan Luo, Han Li, ... Hongyun Zhao in Cellular & Molecular Immunology

    Article Open access 07 December 2023
    

20. Skeletal Stem Cells as the Developmental Origin of Cellular Niches for Hematopoietic Stem and Progenitor Cells

    The skeletal system is a highly complex network of mesenchymal, hematopoietic, and vasculogenic stem cell lineages that coordinate the development...

    Thomas H. Ambrosi, Charles K. F. Chan in Bone Marrow Niche

    Chapter 2021