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Higher dietary glycemic load is inversely associated with stress prevalence among Iranian adults
BackgroundPsychological disorders including depression, anxiety, and stress comprise a huge public health problem. The aim of this cross-sectional...
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Effect of blood flow restriction and electrical muscle stimulation on human glycemic response to a glucose challenge
PurposeTo determine whether reduced tissue oxygen availability through blood flow restriction (BFR) alone, or in combination with electrically...
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Glycemic status, insulin resistance, and mortality from lung cancer among individuals with and without diabetes
BackgroundThe effects of glycemic status and insulin resistance on lung cancer remain unclear. We investigated the associations between both glycemic...
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The effects of glycemic index on prostate cancer progression in a xenograft mouse model
BackgroundPreviously, we found low-carbohydrate diets slowed prostate cancer (PC) growth and increased survival vs. a Western diet in mice, by...
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Investigating the associations of glycemic load and glycemic index with lung cancer risk in the Southern Community Cohort Study
PurposeDiets with a high glycemic load (GL) or glycemic index (GI) may increase cancer risk. Findings from prior studies on the relationship between...
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Quantitative trait loci, G×E and G×G for glycemic traits: response to metformin and placebo in the Diabetes Prevention Program (DPP)
The complex genetic architecture of type-2-diabetes (T2D) includes gene-by-environment (G×E) and gene-by-gene (G×G) interactions. To identify G×E and...
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Carbohydrate quality indices and colorectal cancer risk: a case-control study
BackgroundColorectal cancer (CRC) is the fourth and third most common cancer in Iran and the world, respectively. Carbohydrates can lead to the...
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Urinary Glucose Excretion as a Biomarker for Precision Medicine in Diabetes
Glucosuria has been recognized as a classical biomarker for poor glycemic control among individuals with diabetes. However, the development of...
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Comparing effects of low glycemic index/high-fat, high-calorie diet and high-fat, high-calorie diet on cytokine levels of patients with cystic fibrosis: A randomized controlled clinical trial
The importance of the host inflammatory response, as a central pathological feature of cystic fibrosis, is well recognized. Additionally,...
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Sex-dependent effects of carbohydrate source and quantity on caspase-1 activity in the mouse central nervous system
BackgroundMounting evidence links glucose intolerance and diabetes as aspects of metabolic dysregulation that are associated with an increased risk...
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Untargeted metabolomic profiling reveals molecular signatures associated with type 2 diabetes in Nigerians
BackgroundType 2 diabetes (T2D) has reached epidemic proportions globally, including in Africa. However, molecular studies to understand the...
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Urinary Glucose Excretion as a Biomarker for Precision Medicine In Diabetes
Glucosuria has been recognized as a classical biomarker for poor glycemic control among individuals with diabetes. However, the development of...
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Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake
Distinct tissue-specific mechanisms mediate insulin action in fasting and postprandial states. Previous genetic studies have largely focused on...
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Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake
The carbohydrate–insulin model of obesity posits that high-carbohydrate diets lead to excess insulin secretion, thereby promoting fat accumulation...
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A novel prognostic biomarker in progression free survival for patients with cervical cancer, glucose to c-reactive protein ratio (GCR)
BackgroundCervical cancer is a tumor with high morbidity and mortality. The importance of inflammatory and metabolic parameters affecting...
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Placental IGFBP1 levels during early pregnancy and the risk of insulin resistance and gestational diabetes
Reduced insulin sensitivity (insulin resistance) is a hallmark of normal physiology in late pregnancy and also underlies gestational diabetes...
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Diabetes risk reduction diet and ovarian cancer risk: an Italian case-control study
PurposeTo investigate the relation between a diabetes risk reduction diet (DRRD) and ovarian cancer.
MethodsWe used data from a multicentric...
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Adherence to the Mediterranean diet can beneficially affect the gut microbiota composition: a systematic review
AimDietary patterns could have a notable role in sha** gut microbiota composition. Evidence confirms the positive impact of the Mediterranean diet...
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Association of nutritional glycaemic indices with global DNA methylation patterns: results from the Moli-sani cohort
BackgroundHigh dietary glycaemic index (GI) and load (GL) have been associated with increased risk of various cardiometabolic conditions. Among the...
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Nutrition and Common Diseases
In this chapter, we will provide a first overview of the role of nutrition on our health and risk for disease. During the past 50 years a significant...