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Genetic variation at innate and adaptive immune genes – contrasting patterns of differentiation and local adaptation in a wild gull
Immunogenetic variation in natural vertebrate populations is expected to respond to spatial and temporal fluctuations in pathogen assemblages. While...
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High Genetic Differentiation and Genetic Diversity in Endangered Mahseer Tor khudree (Sykes, 1839) as Revealed from Concatenated ATPase 6/8 and Cyt b Mitochondrial Genes
The Deccan mahseer, Tor khudree (Sykes 1839), belonging to family Cyprinidae is an important food and a game fish distributed in peninsular India....
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Integrative characterization of genetic and phenotypic differentiation in an ant species complex with strong hierarchical population structure and low dispersal abilities
Low dispersal, occurrence of asexual reproduction and geographic discontinuity increase genetic differentiation between populations, which ultimately...
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The Autoimmune Manifestations in Patients with Genetic Defects in the B Cell Development and Differentiation Stages
PurposePrimary B cell defects manifesting as predominantly antibody deficiencies result from variable inborn errors of the B cell lineage and their...
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Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions
BackgroundAge and obesity are dominant risk factors for several common cardiometabolic disorders, and both are known to impair adipose tissue...
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Landscape genomics reveals adaptive genetic differentiation driven by multiple environmental variables in naked barley on the Qinghai-Tibetan Plateau
Understanding the local adaptation of crops has long been a concern of evolutionary biologists and molecular ecologists. Identifying the adaptive...
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Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard
Species distributed across climatic gradients will typically experience spatial variation in selection, but gene flow can prevent such selection from...
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Genetic Differentiation and Relationships of Cottus kolymensis Sideleva et Goto, 2012 (Cottidae)
AbstractFor the first time, a karyological and molecular genetic ( COI , cytochrome b , 16S rRNA genes) study of the freshwater fish species Cottus...
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Genetic differentiation of Plasmodium vivax duffy binding protein in Ethiopia and comparison with other geographical isolates
BackgroundPlasmodium vivax Duffy binding protein (PvDBP) is a merozoite surface protein located in the micronemes of P. vivax . The invasion of human...
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Extensive prevalence and significant genetic differentiation of Blastocystis in high- and low-altitude populations of wild rhesus macaques in China
BackgroundBlastocystis is a common intestinal protist with a wide range of hosts. Thus far, 38 subtypes have been identified. In recent years, wild...
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Genetic differentiation and evolution of broad-leaved evergreen shrub and tree varieties of Daphniphyllum macropodum (Daphniphyllaceae)
Tree form evolution is an important ecological specialization for woody species, but its evolutionary process with adaptation is poorly understood,...
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Differentiation of Peripheral Treg
This chapter shows protocols for the differentiation of peripheral Treg (pTreg) from polyclonal and monoclonal CD4+ T cells. Polyclonal naïve CD4+ T... -
Genetic Differentiation of the Fourhorn Sculpin Myoxocephalus quadricornis (Linnaeus, 1758) and Its Position in the Myoxocephalini Taranetz Tribe (Cottidae: Myoxocephalinae)
A molecular genetic and karyological study of the fourhorn sculpin Myoxocephalus quadricornis (Linnaeus, 1758) has been carried out. The karyotype...
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Stem Cell Differentiation Mediated by Biomaterials/Surfaces
Directing the differentiation of stem cells into a specific stromal lineage such as adipocyte, chondrocyte, fibroblast, myocyte, and osteoblast cell... -
Genetic Differentiation and Clonality in a Local Population of the Caucasian Endemic Trifolium polyphyllum C.A. Mey. (Fabacae)
AbstractTrifolium polyphyllum is a Caucasian endemic of the Fabaceae family peculiar for its inability of nitrogen fixation. Despite this unique...
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Exploring hematopoiesis in zebrafish using forward genetic screening
Zebrafish have emerged as a powerful animal model for investigating the genetic basis of hematopoiesis. Owing to its close genetic and developmental...
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Genetic Structure and Differentiation of Relict Lime Populations Based on the Analysis of Variability of Nuclear Microsatellite Loci
AbstractThe genetic diversity, structure, and differentiation of relict lime plantations in Krasnoyarsk krai (considered as a separate species Tilia...
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Directed Differentiation of Neurons from Human iPSCs for Modeling Neurological Disorders
Human-induced pluripotent stem cell (hiPSC) technology has enabled comprehensive human cell-based disease modeling in vitro. Due to limited... -
Host genetic variation drives the differentiation in the ecological role of the native Miscanthus root-associated microbiome
BackgroundMicrobiome recruitment is influenced by plant host, but how host plant impacts the assembly, functions, and interactions of perennial plant...
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Differentiation of Juniperus deltoidеs R.P. Аdams in the Crimean-Caucasian Region according to the Variability of Microsatellite DNA Markers
AbstractThe structure of genetic variability of the prickly juniper Juniperus deltoides R.P. Adams (family Cupressaceae), an important component of...