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Addition of progesterone to feminizing gender-affirming hormone therapy in transgender individuals for breast development: a randomized controlled trial
BackgroundFeminizing gender-affirming hormone therapy (GAHT) for transgender individuals traditionally includes estradiol and androgen deprivation....
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Gender-affirming hormone therapy induces specific DNA methylation changes in blood
BackgroundDNA methylation is an epigenetic mark that is influenced by underlying genetic profile, environment, and ageing. In addition to X-linked...
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Clinical Pharmacological Considerations in Transgender Medicine
Transgender medicine is a growing clinical field. Hormone therapy (testosterone or estrogen treatment) is part of the standard of gender-affirming...
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Incidence of prostate cancer in transgender women in the US: a large database analysis
The risk of prostate cancer among transgender women undergoing medical and surgical gender-affirming interventions remains unclear, though up to a...
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Effect of testosterone therapy on breast tissue composition and mammographic breast density in trans masculine individuals
BackgroundThe effect of gender-affirming testosterone therapy (TT) on breast cancer risk is unclear. This study investigated the association between...
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Together-Equitable-Accessible-Meaningful (TEAM) Training to Improve Cancer Care for Sexual and Gender Minorities (SGM): Outcomes from a Pilot Study
To alleviate health disparities experienced by sexual and gender minority (SGM) patients, cancer care professionals need further education on the...
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Transgender and gender-diverse (TGD) individuals’ perspectives on research seeking genetic variants associated with TGD identities: a qualitative study
Recent genetic research has explored how genetic variants may contribute to gender dysphoria and transgender and gender-diverse (TGD) identities....
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Educational Initiatives to Improve the Cancer-Related Disparities Facing Transgender and Gender Diverse (TGD) Individuals
Transgender and gender diverse (TGD) individuals face discrimination and experience disparate healthcare, and cancer care, in particular. Our team...
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Cancer surveillance for transgender and gender diverse patients with Lynch syndrome: a practice resource of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
Transgender and gender diverse (TGD) populations with hereditary cancer syndromes face unique obstacles to identifying and obtaining appropriate...
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Prostate cancer in transgender women: considerations for screening, diagnosis and management
Transgender individuals represent 0.55% of the US population, equivalent to 1.4 million transgender adults. In transgender women, feminisation can...
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Cognitive Behavioral Therapy with Diverse Youth
Researchers and clinicians are increasingly recognizing the importance of attending to dimensions of diversityDiversity in clinical work given the...
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Psychedelic-Assisted Therapy for Social Adaptability in Autistic Adults
Access to the Internet has upended long-standing myths and misconceptions about autism as autistic individuals are enabled through technology...
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Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms
Current therapies for high-grade TP53 -mutated myeloid neoplasms (≥10% blasts) do not offer a meaningful survival benefit except allogeneic stem cell...
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Pathophysiological effects of androgens on the female vascular system
Sex hormones and their respective receptors affect vascular function differently in men and women, so it is reasonable to assume they play a role in...
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Markers of vitality in ovaries of transmen after long-term androgen treatment: a prospective cohort study
BackgroundGender-affirming hormone therapy has been hypothesized to reduce the patient’s reproductive potential in transmen, although the exact...
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LGBTQ+ cancer: priority or lip service? A qualitative content analysis of LGBTQ+ considerations in U.S. state, jurisdiction, and tribal comprehensive cancer control plans
The National Comprehensive Cancer Control Program, a Centers for Disease Control and Prevention funded program, supports cancer coalitions across the...
