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1. Synbiotics in Gastric Cancer

   The growth of human gut microbiota is critical for, the metabolism and synthesis of short-chain fatty acids, nutrition absorption and vitamins,...

   Nitin Verma, Komal Thapa, ... Kamal Dua in Synbiotics for the Management of Cancer

   Chapter 2023
   

2. Gastric Cancer: The Microbiome Beyond Helicobacter pylori

   Gastric cancer remains an important global health burden. Helicobacter pylori is the major etiological factor in gastric cancer, infecting the...

   Melissa Mendes-Rocha, Joana Pereira-Marques, ... Ceu Figueiredo in Helicobacter pylori and Gastric Cancer

   Chapter 2023
   

3. Clinical Management of Gastric Cancer Treatment Regimens

   Gastric cancer is the fifth most common cancer and the fourth leading cause of cancer-associated death in the world. Endoscopic resection can be the...

   Juliette Boilève, Yann Touchefeu, Tamara Matysiak-Budnik in Helicobacter pylori and Gastric Cancer

   Chapter 2023
   

4. miR-1286, a Tumor Suppressor of Gastric Cancer, Serves as a Promising Biomarker for Screening Gastric Cancer from Gastritis

   Gastric cancer (GC) is one of the crucial causes of cancer-associated death worldwide. This study aimed to investigate the biological function of...

   Min Tian, Meiquan Jiang, ... Bing Wang in Biochemical Genetics

   Article 13 January 2024
   

5. Other Syndromes and Genes Associated with Gastric Cancer Predisposition

   Gastric cancer is the fifth most common type of cancer and the fourth leading cause of cancer-related death; nevertheless, genetic predisposition to...

   Gianluca Tedaldi, Celina São José, Carla Oliveira in Hereditary Gastric and Breast Cancer Syndrome

   Chapter 2023
   

6. Targeting PRSS23 with tipranavir induces gastric cancer stem cell apoptosis and inhibits growth of gastric cancer via the MKK3/p38 MAPK-IL24 pathway

   Gastric cancer stem cells (GCSCs) contribute to the refractory features of gastric cancer (GC) and are responsible for metastasis, relapse, and drug...

   Ji-xian **ong, Yu-ting Li, ... Li Fu in Acta Pharmacologica Sinica

   Article 09 October 2023
   

7. Clinical Pathogenesis, Molecular Mechanisms of Gastric Cancer Development

   The human pathogen Helicobacter pylori is the strongest known risk factor for gastric disease and cancer, and gastric cancer remains a leading cause...

   Lydia E. Wroblewski, Richard M. Peek Jr in Helicobacter pylori and Gastric Cancer

   Chapter 2023
   

8. Granzyme B Promotes Proliferation, Migration and EMT Process in Gastric Cancer

   Granzyme B (GZMB), a critical member of the Gr gene family, is known to play an essential role in diverse physiological and pathological processes...

   Zhou Lu, **nkun Huang, ... Ying Feng in Biochemical Genetics

   Article 27 May 2024
   

9. Research advances in the molecular classification of gastric cancer

   Gastric cancer (GC) is a malignant tumor with one of the lowest five-year survival rates. Traditional first-line treatment regimens, such as platinum...

   Dike Shi, Zihan Yang, ... Qingqu Guo in Cellular Oncology

   Article Open access 08 May 2024
   

10. Analyzing the expression and clinical significance of CENPE in gastric cancer

    Background

    Gastric cancer (GC) is a prevalent type of malignant gastrointestinal tumor. Many studies have shown that CENPE acts as an oncogene in some...

    **g Wang, **aofei Li, ... Lianyi Guo in BMC Medical Genomics

    Article Open access 03 May 2024
    

11. Drug Repurposing in Gastric Cancer: Current Status and Future Perspectives

    Gastric cancer remains an important contributor to the global cancer burden ranking the 5th most common and the 4th most deadly cancer, according to...

    Marina Leite, Raquel Seruca, Jorge M. Gonçalves in Hereditary Gastric and Breast Cancer Syndrome

    Chapter 2023
    

12. Knocking Down HN1 Blocks Helicobacter pylori-Induced Malignant Phenotypes in Gastric Mucosal Cells and Inhibits Gastric Cancer Cell Proliferation, Cytoskeleton Remodeling, and Migration

    Helicobacter pylori ( H. pylori ) is implicated in the aberrant proliferation and malignant transformation of gastric mucosal cells, heightening the...

    Ying Huang, **aofei Wang, ... Yu Miao in Biochemical Genetics

    Article 25 March 2024
    

13. Identification of Key lncRNAs Associated with Immune Infiltration and Prognosis in Gastric Cancer

    Long non-coding RNAs (lncRNAs), as promising novel biomarkers for cancer treatment and prognosis, can function as tumor suppressors and oncogenes in...

    Wen **, Jianchao Jia, ... Lan Yu in Biochemical Genetics

    Article 24 April 2024
    

14. ALKBH5-mediated CHAC1 depletion promotes malignant progression and decreases cisplatin-induced oxidative stress in gastric cancer

    The m6a demethyltransferase ALKBH5 dynamically modulates gene expression and intracellular metabolic molecules by modifying RNA m6a in cancer cells....

    Chunting Chen, Ertao Zhai, ... Shirong Cai in Cancer Cell International

    Article Open access 25 November 2023
    

15. Mutations in Helicobacter pylori infected patients with chronic gastritis, intestinal type of gastric cancer and familial gastric cancer

    Background

    Development of sequential changes of mucous leading to gastric cancer and familial cases of gastric cancer of intestinal type is widely...

    Andrzej Hnatyszyn, Marlena Szalata, ... Ryszard Słomski in Hereditary Cancer in Clinical Practice

    Article Open access 12 June 2024

16. Genomic and evolutionary characteristics of metastatic gastric cancer by routes

    Background

    In gastric cancer (GC) patients, metastatic progression through the lymphatic, hematogenous, peritoneal, and ovarian routes, is the...

    Jae Eun Lee, Ki Tae Kim, ... Yoon Young Choi in British Journal of Cancer

    Article Open access 08 July 2023
    

17. GGT5 facilitates migration and invasion through the induction of epithelial–mesenchymal transformation in gastric cancer

    Background

    Gamma-glutamyltransferase 5 (GGT5), one of the two members in the GGT family (GGT1 and GGT5), plays a crucial role in oxidative regulation,...

    Zhuang Luo, Yong Chen, ... Jun Ren in BMC Medical Genomics

    Article Open access 05 April 2024
    

18. YY1: a key regulator inhibits gastric cancer ferroptosis and mediating apatinib-resistance

    Objective

    Gastric cancer (GC) stands as a prevalent and deadly global malignancy. Despite its role as a preoperative neoadjuvant therapy, Apatinib’s...

    Zi-Han Geng, Jun-**an Du, ... Yi-Hong Luo in Cancer Cell International

    Article Open access 12 February 2024
    

19. Leveraging synthetic lethality to uncover potential therapeutic target in gastric cancer

    Since trastuzumab was approved in 2012 for the first-line treatment of gastric cancer (GC), no significant advancement in GC targeted therapies has...

    Haigang Geng, Ruolan Qian, ... Chunchao Zhu in Cancer Gene Therapy

    Article 01 December 2023
    

20. The emerging role of glycolysis and immune evasion in gastric cancer

    Gastric cancer (GC) is the fifth most common malignancy and the third leading cause of cancer-related deaths worldwide. Similar to other types of...

    Shanshan Zheng, Huaizhi Li, ... Qingmin Sun in Cancer Cell International

    Article Open access 09 December 2023