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The severity of psychosocial and functional morbidity among facially disfigured untreated noma cases in Ethiopia
ObjectivesNoma is a facially disfiguring disease that affects the oral cavity and midface structures. If left untreated, the disease is fatal. Noma...
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Functional connectivity patterns in parosmia
ObjectiveParosmia is a qualitative olfactory dysfunction presenting as “distorted odor perception” in presence of an odor source. Aim of this study...
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Improved dynamic functional connectivity estimation with an alternating hidden Markov model
Dynamic functional connectivity (DFC) analysis has been widely applied to functional magnetic resonance imaging (fMRI) data to reveal the...
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Recent advances in CRISPR-based functional genomics for the study of disease-associated genetic variants
Advances in sequencing technology have greatly increased our ability to gather genomic data, yet understanding the impact of genetic mutations,...
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Functional and Effective Connectivity Underlying Semantic Verbal Fluency
Semantic verbal fluency (SVF) impairment is present in several neurological disorders. Although activation in SVF-related areas has been reported,...
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Effects of second language acquisition on brain functional networks at different developmental stages
Previous studies have shown that language acquisition influences both the structure and function of the brain. However, whether the acquisition of a...
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A precision functional atlas of personalized network topography and probabilities
Although the general location of functional neural networks is similar across individuals, there is vast person-to-person topographic variability. To...
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Prevention of M2 polarization and temporal limitation of differentiation in monocytes by extracellular ATP
BackgroundElevated levels of extracellular adenosine triphosphate (ATP) modulate immunologic pathways and are considered to be a danger signal in...
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A New Microfluidic Device to Facilitate Functional Precision Medicine Assays
Functional precision medicine (FPM) has emerged as a new approach to improve cancer treatment. Despite its potential, FPM assays present important...
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Structural and functional connectivity associations with anterior cingulate sulcal variability
Sulcation of the anterior cingulate may be defined by presence of a paracingulate sulcus, a tertiary sulcus develo** during the third gestational...
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Selective vulnerability of motor neuron types and functional groups to degeneration in amyotrophic lateral sclerosis: review of the neurobiological mechanisms and functional correlates
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition characterised by a progressive loss of motor neurons controlling voluntary...
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Limitation and Termination of the Immune Response: Influences of Food Components on the Downregulation and Termination of the Immunological Defense Response
Immune reactions must occur in a spatially and temporally limited manner within the framework of physiological homeostasis. Specific functional food...
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A Functional Atlas of the Cerebellum Based on NeuroSynth Task Coordinates
Although the human cerebellum has a surface that is about 80% of that of the cerebral cortex and has about four times as many neurons, its functional...
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Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms
A genetic system, ProTracer, has been recently developed to record cell proliferation in vivo. However, the ProTracer is initiated by an infrequently...
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Functional Impairments in the Large-Scale Resting Networks of the Brain in Opioid Addiction
Objectives. To assess the functional state of large-scale resting brain networks in patients with opioid intoxication. Materials and methods. A total...
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Functional MRI radiomics-based assessment of pelvic bone marrow changes after concurrent chemoradiotherapy for cervical cancer
ObjectivesTo quantify the dose-response relationship of changes in pelvic bone marrow (PBM) functional MR radiomic features (RF) during concurrent...
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Synaptic Tagging and Capture: Functional Implications and Molecular Mechanisms
This chapter introduces the concept of synaptic tagging and capture, which was first identified in electrophysiological studies in hippocampal brain...
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Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that recognize microbial metabolites through a semi-invariant T cell receptor...
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Neuropsychological and Functional Assessment of Cognitive Impairments in Schizophrenia
Cognitive deficits are a central feature of psychotic disorders. Their impact and relevance for clinical prognosis and functional recovery, together...
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Decoding Single and Paired Phonemes Using 7T Functional MRI
Several studies have shown that mouth movements related to the pronunciation of individual phonemes are represented in the sensorimotor cortex. This...
