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Control of Rhipicephalus microplus on taurine cattle with fluralaner in a subtropical region
BackgroundIn Rio Grande do Sul, Brazil, a region with a subtropical climate, Rhipicephalus microplus is present in taurine cattle raised for beef...
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Topical, contact, and oral susceptibility of adult Culicoides biting midges (Diptera: Ceratopogonidae) to fluralaner
BackgroundCulicoides biting midges (Diptera: Ceratopogonidae) are economically important blood-feeding pests closely associated with livestock...
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Treatment of dogs with Bravecto® (fluralaner) reduces mosquito survival and fecundity
BackgroundMosquitoes serve as the vector of canine heartworm ( Dirofilaria immitis ), which represents a significant and persistent threat to canine...
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Insecticidal activity of fluralaner (Exzolt®) administered to Gallus gallus domesticus against triatomines (Hemiptera, Reduviidae, Triatominae)
BackgroundTriatoma infestans, Triatoma brasiliensis , Triatoma pseudomaculata and Rhodnius prolixus are vectors of Trypanosoma cruzi , the etiological...
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Two protocols using fluralaner for Rhipicephalus microplus strategic control on taurine cattle in a tropical region
BackgroundThe present study aimed to evaluate the effects of different treatment strategies using a new commercial formulation containing pour-on...
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Effect of fluralaner on the biology, survival, and reproductive fitness of the neotropical malaria vector Anopheles aquasalis
BackgroundReducing mosquito abundance or interfering with its ability to support the parasite cycle can help to interrupt malaria in areas of...
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Pharmacokinetics of fluralaner as a systemic drug to control infestations of the common bed bug, Cimex lectularius, in poultry facilities
BackgroundBed bug infestations are re-emerging in the poultry industry throughout the USA. Although the impacts of bed bugs on birds’ health and...
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Fluralaner systemic treatment of chickens results in mortality in Triatoma gerstaeckeri, vector of the agent of Chagas disease
BackgroundChagas disease remains a persistent vector-borne neglected tropical disease throughout the Americas and threatens both human and animal...
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Efficacy of either orally administered fluralaner or topically administered imidacloprid/flumethrin for controlling Rhipicephalus sanguineus sensu lato premises infestations
BackgroundAdult, nymph, and larval Rhipicephalus sanguineus sensu lato infest dogs and thrive in premises including homes and kennels. Ticks emerge...
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Year-round efficacy of a single treatment of fluralaner injectable suspension (Bravecto QuantumTM) against repeated infestations with Ixodes holocyclus in dogs
BackgroundThe longer the duration of protection of an acaricide against canine infestation with Ixodes holocyclus , the lower the risk of gaps in...
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Evaluation of the scabicidal effect of a single dose of fluralaner in a rabbit model of crusted scabies
Recently, scabies was included in the WHO roadmap for neglected tropical diseases 2021–2030. Till now, ivermectin is the only available oral drug...
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Field efficacy of fluralaner (Bravecto® chewable tablets) for preventing Babesia canis infection transmitted by Dermacentor reticulatus ticks to dogs
BackgroundThe isoxazoline fluralaner is effective for prevention of Babesia canis transmission from infected Dermacentor reticulatus ticks to dogs...
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Year-round efficacy of a single treatment of fluralaner injectable suspension (Bravecto Quantum™) against repeated infestations with Rhipicephalus sanguineus (sensu lato) and Ctenocephalides felis in dogs
BackgroundPoor owner compliance with monthly control measures means that dogs in Australia can remain susceptible to infestations with fleas, present...
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Efficacy of fluralaner chewable tablets (Bravecto®) against Asian longhorned tick (Haemaphysalis longicornis) infestations of dogs
BackgroundThe parthenogenic reproductive ability of Haemaphysalis longicornis , facilitating quick life cycle completion and rapid geographic spread...
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Fluralaner (Bravecto®) treatment kills Aedes aegypti after feeding on Dirofilaria immitis-infected dogs
BackgroundTransmission of canine heartworm ( Dirofilaria immitis ) from infected to naïve dogs is dependent on successful mosquito feeding and...
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Efficiency of fluralaner pour-on in different strategic control protocols against Rhipicephalus microplus on Brangus cattle in a tropical area
BackgroundThe occurrence of higher winter temperatures in Brazilian areas with tropical and highland climates may result in a fifth peak of tick...
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Efficacy of two topical fluralaner formulations (Bravecto®; Bravecto® Plus) against Asian longhorned tick (Haemaphysalis longicornis) infestations of cats
BackgroundThe invasive tick species, Haemaphysalis longicornis , is becoming established in the USA, presenting a growing threat to dogs and cats....
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Assessment of the in vitro acaricidal activity of Bravecto® (fluralaner) and a proposed orange oil-based formulation vehicle for the treatment of Sarcoptes scabiei
BackgroundSarcoptic mange is a serious animal welfare concern in bare-nosed wombats ( Vombatus ursinus ). Fluralaner (Bravecto ® ) is a novel acaricide...
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First report of the efficacy of a fluralaner-based pour-on product (Exzolt® 5%) against ectoparasites infesting cattle in Brazil
BackgroundThis study describes the effectiveness of a novel active pharmaceutical ingredient, fluralaner (isoxazoline class), against important...
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Fluralaner 5.46% (w/w) flavored chewable tablet (Bravecto® 1-Month) is effective for treatment of canine generalized demodicosis
BackgroundOrally administered fluralaner (13.64% w/w) is effective for treating canine generalized demodicosis. A study was initiated to assess the...